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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
66 Results for "
IP1
" in MedChemExpress (MCE) Product Catalog:
Products (66)
66 Results for "IP1" in MCE Product Catalog:
2
2 Cited Publications
Referencia número: HY-P3419
No. CAS: 929905-12-4
Áreas de investigación:
1
1 Cited Publications
Synonyms: Inositol 1,4,5-trisphosphate trisodium; Ins(1,4,5)-P3 trisodium
Target:
Áreas de investigación:
D-myo-Inositol-1,4,5-triphosphate sodium salt is the trisodium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.
1
1 Cited Publications
Referencia número: HY-103642
No. CAS: 103476-24-0
Synonyms: Inositol 1,4,5-trisphosphate hexapotassium salt; Ins(1,4,5)-P3 hexapotassium salt
Target:
Áreas de investigación:
D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is the hexapotassium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.
Áreas de investigación:
AZ8838 is a potent, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pKi of 6.4 for hPAR2 [1].
Referencia número: HY-169396
No. CAS: 2769753-10-6
Synonyms: TL13-87
Target:
Ligands for Target Protein for PROTAC Microtubule/Tubulin YTHDF CDK Btk FLT3 Aurora Kinase Tyrosinase ULK Itk
Áreas de investigación:
TAE648 is a target protein ligand of PROTAC SK-3-91 (HY-137341) (Ligand for Target Protein for PROTAC). TAE648 can be used for synthesis PROTAC [1]. TAE648 decreases monolayer-cultured SKOV3ip1 cell viability .
Referencia número: HY-112603
No. CAS: 1623194-37-5
Target:
Áreas de investigación:
AP5 is a potent, orlly active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 demonstrates rat and human inositol monophosphate (IP1) EC50 values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 has the potential for type II diabetes research [1].
Referencia número: HY-176920
No. CAS: 920707-33-1
Target:
Áreas de investigación:
BRI-12349 (Compound 50) is a dual antagonist of CysLT1R/CysLT2R with Ki values of 1.03 and 6.46 μM. BRI-12349 can inhibit the generation of IP1 induced by LTD4 (the main ligand of CysLTs). BRI-12349 can be used for the research of immunology and inflammation, such as asthma [1].
Referencia número: HY-P3799
No. CAS: 61123-13-5
Target:
Áreas de investigación:
Referencia número: HY-W565924
No. CAS: 935685-90-8
Áreas de investigación:
STX107 is a metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulator (NAM) with a pKi of 8.32. STX107 inhibits glutamate-induced Ca 2+ mobilization, IP1 accumulation, and ERK1/2 phosphorylation. STX107 also inhibits glutamate-induced mGlu5 internalization [1].
Referencia número: HY-177079S
No. CAS: 2759134-55-7
Referencia número: HY-P11041
Target:
Áreas de investigación:
Referencia número: HY-112603A
No. CAS: 1623143-67-8
Target:
Áreas de investigación:
AP5 sodium is a potent, orall active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 sodium demonstrates rat and human inositol monophosphate (IP1) EC50 values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 sodium has the potential for type II diabetes research [1].
Referencia número: HY-P3419A
Áreas de investigación:
Referencia número: HY-RS00994
Target:
Áreas de investigación:
ARL6IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for ARL6IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS02119
Target:
Áreas de investigación:
CCNB1IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for CCNB1IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS06549
Target:
Áreas de investigación:
IER3IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for IER3IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS08124
Target:
Áreas de investigación:
MAPK8IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MAPK8IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS08435
Target:
Áreas de investigación:
MID1IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MID1IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS09986
Target:
Áreas de investigación:
PAK1IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for PAK1IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS10306
Target:
Áreas de investigación:
PDZK1IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for PDZK1IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
