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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
66 Results for "
IP1
" in MedChemExpress (MCE) Product Catalog:
Products (66)
66 Results for "IP1" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P3419
CAS No.: 929905-12-4
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1
1 Cited Publications
Synonyms: Inositol 1,4,5-trisphosphate trisodium; Ins(1,4,5)-P3 trisodium
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D-myo-Inositol-1,4,5-triphosphate sodium salt is the trisodium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.
1
1 Cited Publications
Cat. No.: HY-103642
CAS No.: 103476-24-0
Synonyms: Inositol 1,4,5-trisphosphate hexapotassium salt; Ins(1,4,5)-P3 hexapotassium salt
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D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is the hexapotassium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.
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AZ8838 is a potent, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pKi of 6.4 for hPAR2 [1].
Cat. No.: HY-169396
CAS No.: 2769753-10-6
Synonyms: TL13-87
Target:
Ligands for Target Protein for PROTAC Microtubule/Tubulin YTHDF CDK Btk FLT3 Aurora Kinase Tyrosinase ULK Itk
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TAE648 is a target protein ligand of PROTAC SK-3-91 (HY-137341) (Ligand for Target Protein for PROTAC). TAE648 can be used for synthesis PROTAC [1]. TAE648 decreases monolayer-cultured SKOV3ip1 cell viability .
Cat. No.: HY-112603
CAS No.: 1623194-37-5
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AP5 is a potent, orlly active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 demonstrates rat and human inositol monophosphate (IP1) EC50 values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 has the potential for type II diabetes research [1].
Cat. No.: HY-176920
CAS No.: 920707-33-1
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BRI-12349 (Compound 50) is a dual antagonist of CysLT1R/CysLT2R with Ki values of 1.03 and 6.46 μM. BRI-12349 can inhibit the generation of IP1 induced by LTD4 (the main ligand of CysLTs). BRI-12349 can be used for the research of immunology and inflammation, such as asthma [1].
Cat. No.: HY-P3799
CAS No.: 61123-13-5
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Cat. No.: HY-W565924
CAS No.: 935685-90-8
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STX107 is a metabotropic glutamate 5 (mGlu5) receptor negative allosteric modulator (NAM) with a pKi of 8.32. STX107 inhibits glutamate-induced Ca 2+ mobilization, IP1 accumulation, and ERK1/2 phosphorylation. STX107 also inhibits glutamate-induced mGlu5 internalization [1].
Cat. No.: HY-177079S
CAS No.: 2759134-55-7
Cat. No.: HY-P11041
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Cat. No.: HY-112603A
CAS No.: 1623143-67-8
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AP5 sodium is a potent, orall active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 sodium demonstrates rat and human inositol monophosphate (IP1) EC50 values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 sodium has the potential for type II diabetes research [1].
Cat. No.: HY-P3419A
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Cat. No.: HY-RS00994
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ARL6IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for ARL6IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02119
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CCNB1IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for CCNB1IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS06549
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IER3IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for IER3IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08124
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MAPK8IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MAPK8IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS08435
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MID1IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for MID1IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09986
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PAK1IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for PAK1IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10306
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PDZK1IP1 Human Pre-designed siRNA Set A contains three designed siRNAs for PDZK1IP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
