8559 Results for "

SARS-CoV-2 RNA detection

" in MedChemExpress (MCE) Product Catalog:
Products (8559)

8559 Results for "SARS-CoV-2 RNA detection" in MCE Product Catalog:

1351
1351 Publications Verification
Cat. No.: HY-17589
CAS No.: 50-63-5
Chloroquine phosphate is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine phosphate is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine phosphate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM) [2] .
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1351
1351 Publications Verification
Cat. No.: HY-17589A
CAS No.: 54-05-7
Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM) [2] .
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1351
1351 Publications Verification
Cat. No.: HY-17589B
CAS No.: 3545-67-3
Chloroquine dihydrochloride is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine dihydrochloride is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine dihydrochloride is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC50=1.13 μM) [2] .
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230
230 Cited Publications
Cat. No.: HY-104077
CAS No.: 1809249-37-3
Purity:  99.95%
Synonyms: GS-5734
Research Areas:  

Infection

Remdesivir (GS-5734) is a nucleoside analogue with effective antiviral activity. Remdesivir can inhibit the synthesis of viral DNA or RNA. Remdesivir can be used for the research of infection, such as SARS-CoV and MHV infection [2] .
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196
196 Cited Publications
Cat. No.: HY-D0079
CAS No.: 104821-25-2
Synonyms: Hydroethidine; PD-MY 003
Dihydroethidium, also known as DHE, is a peroxide indicator. Dihydroethidium penetrates cell membranes to form a fluorescent protein complex with blue fluoresces. After entering the cells, Dihydroethidium is mainly localized in the cell membrane, cytoplasm and nucleus, and the staining effect is the strongest in the nucleus. Dihydroethidium produces inherent blue fluorescence with a maximum excitation wavelength of 370 nm and a maximum emission wavelength of 420 nm; after dehydrogenation, Dihydroethidium combines with RNA or DNA to produce red fluorescence with a maximum excitation wavelength of 300 nm and a maximum emission wavelength of 610 nm. 535 nm can also be used as the excitation wavelength for actual observation .
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168
168 Cited Publications
Cat. No.: HY-D0815
CAS No.: 25535-16-4
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.
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158
158 Cited Publications
Cat. No.: HY-13433
CAS No.: 67526-95-8
Purity:  99.87%
Thapsigargin, an endoplasmic reticulum (ER) stress inducer, is an inhibitor of microsomal Ca 2+-ATPase. Thapsigargin efficiently inhibits coronavirus (HCoV-229E, MERS-CoV, SARS-CoV-2) replication in different cell types [2] .
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134
134 Cited Publications
Cat. No.: HY-D0718
CAS No.: 7385-67-3
Synonyms: Nile Blue A oxazone; Phenoxazone 9
Target:  

Fluorescent Dye

Research Areas:  

Others

Nile red (Nile blue oxazone) is a lipophilic stain. Nile red has environment-sensitive fluorescence. Nile red is intensely fluorescent in a lipid-rich environment while it has minimal fluorescence in aqueous media. Nile red is an excellent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytof uorometry. Nile red stains intracellular lipid droplets red. The fluorescence wavelength is 543/598 nm .
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120
120 Cited Publications
Cat. No.: HY-15005
CAS No.: 1190307-88-0
Purity:  99.97%
Synonyms: GS-7977; PSI-7977
Target:  

HCV

Research Areas:  

Infection Cancer

Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM .
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112
112 Cited Publications
Cat. No.: HY-138687
CAS No.: 2628280-40-8
Purity:  99.74%
Synonyms: PF-07321332
Target:  

SARS-CoV

Research Areas:  

Infection Inflammation/Immunology

Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CL PRO) inhibitor. Nirmatrelvir (PF-07321332) targets to the SARS-CoV-2 virus and can be used for COVID-19 research .
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95
95 Cited Publications
Cat. No.: HY-B1370
CAS No.: 747-36-4
Synonyms: HCQ sulfate
Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro [2] .
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95
95 Cited Publications
Cat. No.: HY-W031727
CAS No.: 118-42-3
Hydroxychloroquine (HCQ) is a synthetic oral antimalarial drug that can be used in the study of malaria and autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. Hydroxychloroquine is a potent autophagic flux inhibitor with antiviral activity (such as SARS-CoV-2 virus) that inhibits Toll-like receptor 7/9 (TLR7/9) signaling [2] .
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92
92 Cited Publications
Cat. No.: HY-D0041
CAS No.: 148504-34-1
Synonyms: Calcein acetoxymethyl ester
Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .
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89
89 Cited Publications
Cat. No.: HY-K1073

MCE Annexin V-FITC/PI Apoptosis Detection Kit provides a rapid and convenient method to detect cell apoptosis and necrosis. After staining, live cells show little or no fluorescence (Annexin V-/PI-), early apoptosis cells show green fluorescence(Annexin V+/PI-), late apoptosis cells and necrosis cells show red and green fluorescence (Annexin V+/PI+).


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87
87 Cited Publications
Cat. No.: HY-15910
CAS No.: 59-14-3
Purity:  99.89%
Synonyms: BrdU; 5-Bromo-2'-deoxyuridine; Bromodeoxyuridine
5-BrdU (BrdU) is a nucleoside analog that competes with thymidine for incorporation into DNA. 5-BrdU is commonly used in the detection of proliferating cells.
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84
84 Cited Publications
Cat. No.: HY-116215
CAS No.: 186689-07-6
Purity:  99.74%
Target:  

Fluorescent Dye

Research Areas:  

Others

2-NBDG is a fluorescently-labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues. It is also used as a topical contrast reagent for the detection of neoplasia. 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry. The probe can be excited by the Argon laser at 488 nm to give the environment-sensitive fluorescence. It has lower photostability than the rhodamine-based fluorescent probes.
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79
79 Cited Publications
Cat. No.: HY-13704
CAS No.: 86639-52-3
Purity:  99.94%
Synonyms: 7-Ethyl-10-hydroxycamptothecin
SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 can bind to RPL15. SN-38 inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. SN-38 is a payload of sacituzumab govitecan (HY -132254) [2] .
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78
78 Cited Publications
Cat. No.: HY-135853
CAS No.: 2492423-29-5
Purity:  99.85%
Synonyms: EIDD-2801; MK-4482
Research Areas:  

Infection

Molnupiravir (EIDD-2801) is an orally bioavailable proagent of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza [2].
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75
75 Cited Publications
Cat. No.: HY-135748
CAS No.: 42424-50-0
Purity:  99.4%
Synonyms: Poly(I:C) sodium
Polyinosinic-polycytidylic acid (Poly(I:C)) sodium is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis [2].
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73
73 Cited Publications
Cat. No.: HY-107202
CAS No.: 24939-03-5
Purity:  99.40%
Synonyms: Poly(I:C)
Polyinosinic-polycytidylic acid (Poly(I:C)) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid can directly trigger cancer cells to undergo apoptosis [2].
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