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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
Tetrahydrofolic acid
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "Tetrahydrofolic acid" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: L-5,6,7,8-Tetrahydrofolic acid; L-Tetrahydrofolic acid
Category:
Human Gut Microbiota Metabolites Microorganisms Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Synonyms: 4-Aminofolic acid; APGA
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Research Areas:
Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia .
Cat. No.: HY-112169A
CAS No.: 914800-65-0
Target:
Target:
Cat. No.: HY-14520S
CAS No.: 1356841-72-9
Cat. No.: HY-14520S1
Synonyms: L-5,6,7,8-Tetrahydrofolic acid-13C5; L-Tetrahydrofolic acid-13C5
Cat. No.: HY-14520A
CAS No.: 71963-69-4
Synonyms: (6S)-5,6,7,8-Tetrahydrofolic acid
Target:
Synonyms: 5-Methyl THF-d3; 5-MTHF-d3
Cat. No.: HY-14520B
CAS No.: 150731-85-4
Synonyms: L-5,6,7,8-Tetrahydrofolic acid trihydrochloride; L-Tetrahydrofolic acid trihydrochloride
Target:
Research Areas:
Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid) trihydrochloride is the biologically active vitamin B9 folate derivative. Tetrahydrofolic acid trihydrochloride is a donor of one-carbon groups for amino acids, nucleic acids, and lipids. Tetrahydrofolic acid trihydrochloride serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid .
Cat. No.: HY-18062S
CAS No.: 1189936-99-9
Synonyms: Aditoprim
Target:
Research Areas:
Aditoprime (Aditoprim) is a selective bacterial dihydrofolate reductase (DHFR) inhibitor with IC50s of 47 and 520 nM for E.coli and L.casei DHFR, respectively. Aditoprime inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime has a broad-spectrum antibacterial activity and excellent pharmacokinetics .
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Research Areas:
Aminopterin (Standard) is the analytical standard of Aminopterin. This product is intended for research and analytical applications. Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia .
Synonyms: L-5,6,7,8-Tetrahydrofolic acid (Standard); L-Tetrahydrofolic acid (Standard)
Cat. No.: HY-14518A
CAS No.: 58602-66-7
Synonyms: 4-Aminofolic acid sodium; APGA sodium
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Research Areas:
Aminopterin sodium (4-Aminofolic acid sodium) is an anti-tumor drug with immunosuppressive activity. Aminopterin sodium blocks the metabolism of folic acid by inhibiting the activity of dihydrofolate reductase, thereby affecting nucleic acid synthesis. Aminopterin sodium is mainly used to inhibit acute lymphoblastic leukemia and certain other types of cancer. Aminopterin sodium is also used clinically as an immunosuppressant to suppress autoimmune diseases .
Cat. No.: HY-139743R
CAS No.: 56066-63-8
Synonyms: Aditoprim (Standard)
Target:
Research Areas:
Aditoprime (Standard) is a selective bacterial dihydrofolate reductase (DHFR) inhibitor with IC50s of 47 and 520 nM for E.coli and L.casei DHFR, respectively. Aditoprime inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime has a broad-spectrum antibacterial activity and excellent pharmacokinetics .
Cat. No.: HY-177337
CAS No.: 56066-19-4
Synonyms: N-Didesmethyl-ADP
Target:
Research Areas:
N-Didesmethyladitoprim is a metabolite of Aditoprime (HY-139743). Aditoprime is a selective bacterial dihydrofolate reductase (DHFR) inhibitor with IC50s of 47 and 520 nM for E.coli and L.casei DHFR , respectively. Aditoprime inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime has a broad-spectrum antibacterial activity and excellent pharmacokinetics .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
