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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
48 Results for "
XO
" in MedChemExpress (MCE) Product Catalog:
Products (48)
48 Results for "XO" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: TEI 6720; TMX 67
Target:
Research Areas:
Febuxostat (TEI 6720) is a potent, selective and non-purine xanthine oxidase (XO) inhibitor with a Ki value of 0.6 nM. Febuxostat has the potential for the research of hyperuricemia and gout .
6
Target:
Research Areas:
Xanthine oxidase, Microorganism (XO) is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS), catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid .
4
Category:
Fagaceae Extract Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Macaranga denticulata (Blume) Müll. Arg. Cancer
Target:
3
3 Cited Publications
Synonyms: Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene
1
1
1 Cited Publications
Cat. No.: HY-N3220
CAS No.: 15648-86-9
Category:
Flavonols Flavonoids Rhododendron dauricum Linn. Metabolic Disease Phenols Polyphenols Ericaceae Extract Plants Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-N0814A
CAS No.: 123408-98-0
Synonyms: Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate
1
1 Cited Publications
Cat. No.: HY-W110883
CAS No.: 3618-43-7
1
Category:
Flavonols Flavonoids Rosaceae Extract Prunus domestica L. Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-W047187
CAS No.: 117405-51-3
Target:
Cat. No.: HY-14268R
CAS No.: 144060-53-7
Synonyms: TEI 6720 (Standard); TMX 67 (Standard)
Target:
Research Areas:
Febuxostat (Standard) is the analytical standard of Febuxostat. This product is intended for research and analytical applications. Febuxostat (TEI 6720) is a potent, selective and non-purine xanthine oxidase (XO) inhibitor with a Ki value of 0.6 nM. Febuxostat has the potential for the research of hyperuricemia and gout .
Cat. No.: HY-146273
CAS No.: 2411698-59-2
Target:
Research Areas:
Xanthine oxidase-IN-7 (compound1h) is a potent andorally active XO (xanthine oxidase) inhibitor with an IC50 of 0.36 µM. Xanthine oxidase-IN-7 effectively reduces serum uric acid levels. Xanthine oxidase-IN-7 has the potential for the research of hyperuricemia and gout .
Cat. No.: HY-N9783
CAS No.: 73086-04-1
Synonyms: B2-3′-G; Epicatechin-(4β,8)-epicatechin gallate
Category:
Phenols Polyphenols Crassulaceae Extract Plants Rhodiola crenulata (HK. f. et.Thoms) H. Ohba
Target:
Cat. No.: HY-151173
CAS No.: 2831329-35-0
Target:
Research Areas:
XO/COX/LOX-IN-1 is a XO/COX/LOX inhibitor with an IC50 of 3.2 μM against rat XO, 10.83 μM against 5-LOX, 12.67 μM against COX-1, and 8.31 μM against COX-2. XO/COX/LOX-IN-1 binds to the active sites of XO, 5-LOX, COX-1 and COX-2, thereby blocking enzyme activities associated with uric acid, leukotriene, prostaglandin synthesis and inflammatory pathways. XO/COX/LOX-IN-1 can be used in the research of hyperuricemia and inflammation .
Cat. No.: HY-N1162
CAS No.: 48236-96-0
Synonyms: Amentoflavanone
Target:
Cat. No.: HY-129889
CAS No.: 1351692-92-6
Synonyms: FebuXOstat acyl-β-D-glucuronide
Target:
Research Areas:
Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) is a metabolite of Febuxostat (HY-14268). Febuxostat is a potent, selective and non-purine xanthine oxidase (XO) inhibitor .
Cat. No.: HY-N0814B
CAS No.: 34367-89-0
Synonyms: Inositol hexaphosphate hexasodium; SNF472
Target:
Research Areas:
URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1, with IC50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1, with a Ki value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia .
Cat. No.: HY-159581
CAS No.: 2089040-93-5
URAT1&XO inhibitor 3 (compound 27) is an orally active anti-gout agent targeting XO (IC50: 35 nM) and URAT1 (IC50: 31 nM). URAT1&XO inhibitor 3 has good pharmacological and pharmacokinetic (PK) characteristics and in vivo safety .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
