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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
boronic acid derivative
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "boronic acid derivative" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-D1553
CAS No.: 1029138-21-3
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(1R,2S)-Xeruborbactam disodium is a boronic acid derivative .
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tert-Butyl carbazate serves as a starting material for the preparation of heterocyclic and hydrazine derivatives. tert-Butyl carbazate undergoes coupling with aryl, heteroaryl, and alkenyl boronic acids to synthesize doubly protected monosubstituted hydrazines. Derivatives of tert-Butyl carbazate exhibit varying degrees of inhibitory activity against Gram-positive bacteria, Gram-negative bacteria, and various fungi .
Cat. No.: HY-W014815
CAS No.: 223463-14-7
Synonyms: 2-Bromopyridine-5-boronic acid
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BPBA (2-Bromopyridine-5-boronic acid) is a derivatization reagent derived from Boric acid (HY-Y0314) with enhanced ionization efficiency in positive-mode electrospray ionization mass spectrometry. BPBA forms boronate ester derivatives with vicinal diols. It enables rapid, catalyst-free labeling operations, improves the detection sensitivity of liquid chromatography/mass spectrometry, and reduces false positive errors .
Cat. No.: HY-32748
CAS No.: 41404-58-4
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2-Bromo-5-fluoropyridine acts as a bromofluoropyridine starting material and an azaaryl halide coupling partner. 2-Bromo-5-fluoropyridine participates in an oxygen-promoted, ligand-free Pd (OAc)2-catalyzed Suzuki reaction, reacting with arylboronic acids to produce 5-fluoro-2-aryl-substituted pyridine derivatives. 2-Bromo-5-fluoropyridine can be used to synthesize 5-fluoro-2-(4-(methylsulfonyl) phenyl) pyridine, an intermediate of the GPR119 agonist GSK1292263A .
Cat. No.: HY-W000854
CAS No.: 10365-98-7
Synonyms: 3-Methoxyphenylboronic acid
Cat. No.: HY-42045
CAS No.: 321724-19-0
Cat. No.: HY-W133954
CAS No.: 10555-76-7
Cat. No.: HY-W000808
CAS No.: 123088-59-5
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(4-Carbamoylphenyl) boronic acid is a boronic acid derivative bearing an amide functional group, and serves as a precursor for organic transformation reactions .
Cat. No.: HY-32928
CAS No.: 126747-14-6
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4-Cyanobenzeneboronic acid is a boronic acid derivative and also coupling reagent in Suzuki cross-coupling reactions .
Cat. No.: HY-W004698
CAS No.: 628692-15-9
Cat. No.: HY-W005558
CAS No.: 851524-96-4
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6-Aminopyridine-3-boronic acid is a boronic acid derivative. Boronic acid derivatives are widely used in organic synthesis for carbon-carbon bond formation. In Suzuki coupling, aryl halides and boronic acid aryl or vinyl esters or boronic acid are coupled using Pd(PPh3)4. It can be used as a pharmaceutical intermediate [1] .
Cat. No.: HY-142920
CAS No.: 2671040-07-4
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LMP7-IN-1, a Boronic acid derivative, is a potent and selective immunoproteasome subunit LMP7 (β5i) inhibitor with an IC50 of 1.83 nM (WO2021143923A1; compound 20) .
Cat. No.: HY-D1349
CAS No.: 2006345-35-1
Cat. No.: HY-137831
CAS No.: 562823-84-1
TLBC, a boronic-chalcone derivative, shows a dose-dependent inhibition with IC50 values of 5.5-25.5 μM in various glioma cell lines. TLBC induces apoptosis independent of changes to the tumor suppressor p53 .
Cat. No.: HY-150766
CAS No.: 2232877-85-7
KPC-2-IN-1, boronic acid derivative, is a potent KPC-2 inhibitor with Ki of 0.032 μM. KPC-2-IN-1 enhances the activity of cefotaxime in KPC-2 expressing E. coli. KPC-2-IN-1 exhibits well tolerated in human HEK-293 cells, which can be used for the study of E. coli resistance to β-lactam antibiotics .
Cat. No.: HY-184697
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Anticancer agent 334 is a quinoxaline derivative containing a trifluoromethyl-substituted boronic acid, with low cytotoxicity and enhanced boron uptake activity. Anticancer agent 334 increases boron accumulation in MDA-MB-231 and HepG2 cells, and achieves higher tumor boron enrichment in tumor-bearing mouse models in vivo. Anticancer agent 334 can serve as a boron carrier and be used in studies related to boron neutron capture therapy for triple-negative breast cancer and hepatocellular carcinoma .
Cat. No.: HY-W134304
CAS No.: 7775-19-1
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Sodium metaborate is a borax derivative and boron source, which serves as a precursor to sodium borohydride, a hydrogen storage medium. Sodium metaborate is commonly used in chemical industry-related research, such as textile processing and corrosion inhibition .
Cat. No.: HY-W000854S
CAS No.: 2241867-05-8
Synonyms: 3-Methoxyphenylboronic acid-d3
Cat. No.: HY-183322
Antiviral agent 83 is a boronic acid-modified Neocryptolepine (HY-E70250) derivative and is an anti-HPV agent. Antiviral agent 83 bind to the viral capsid protein and/or envelope protein, inducing conformational changes that effectively obstruct the interaction between the virus and host cell receptors. Antiviral agent 83 exhibits inhibitory activity against multiple high-risk HPV strains. Antiviral agent 83 inhibits HPV infection in vitro and in vaginal tract in vivo .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
