444 Results for "

cell imaging

" in MedChemExpress (MCE) Product Catalog:
Products (444)

444 Results for "cell imaging" in MCE Product Catalog:

34
Coppersensor 1
Coppersensor 1
0 Images
34 Publications Verification
Cat. No.: HY-141511
CAS No.: 874748-20-6
Purity:  97.74%
Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu + with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu +) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .
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18
DFHBI-1T
DFHBI-1T
0 Images
18 Cited Publications
Cat. No.: HY-110251
CAS No.: 1539318-36-9
Purity:  98.11%
DFHBI-1T is a membrane-permeable RNA aptamers-activated fluorescence probe (ex/em=472 nm/507 nm). DFHBI-1T binds to RNA aptamers (Spinach, Spinach2, iSpinach, and Broccoli) and causes specific fluorescence and lower background fluorescence. DFHBI-1T is used to image RNA in live cells .
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11
TRFS-green
TRFS-green
0 Images
11 Cited Publications
Cat. No.: HY-115640
CAS No.: 1513848-14-0
Purity:  95.02%
Target:  

TrxR

Research Areas:  

Others

TRFS-green is a highly selective off−on fluorescent probe for imaging selenoprotein thioredoxin reductase (TrxR) in living cells. TRFS-green has the maximum absorbance at around 373 nm. After it is activated by TrxR, the maximum absorbance shifts to around 440 nm .
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7
DFHBI
DFHBI
0 Images
7 Cited Publications
Cat. No.: HY-110250
CAS No.: 1241390-29-3
Purity:  98.85%
DFHBI is a small molecule that resembles the chromophore of green fluorescent protein (GFP). DFHBI can be used for imaging RNA in living cells. . Spinach and DFHBI are essentially nonfluorescent when unbound, whereas the Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells (Ex/Em = 469/501 nm).
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7
IR-780
IR-780
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7 Cited Publications
Cat. No.: HY-D1063
CAS No.: 207399-07-3
IR-780 is a near-infrared fluorescent probe for in vivo imaging of tumor cells. IR-780 is transported into tumor cells via OATPs and ABCB10, with uptake dependent on glycolytic activity and plasma membrane potential. IR-780 preferentially accumulates in tumor cell mitochondria, including those of drug-resistant cancer cells, without chemical conjugation. IR-780 generates reactive oxygen species (ROS), induces hyperthermia and apoptosis, inhibits tumor growth and recurrence, and modulates HSP70 expression upon ultrasound or 808 nm laser exposure. IR-780 acts as a sonosensitizer, photodynamic and photothermal agent, and drug delivery carrier, with low acute imaging-dose toxicity and rapid vital organ clearance. IR-780 can be used for the research of cancer, such as breast cancer, lung cancer, and non-small cell lung cancer (NSCLC) .
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4
CCZ01048 TFA
CCZ01048 TFA
0 Images
4 Cited Publications
Cat. No.: HY-P2336A
Target:  

Melanocortin Receptor

Research Areas:  

Cancer

CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
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4
HBC
HBC
0 Images
4 Cited Publications
Cat. No.: HY-D1373
CAS No.: 156840-13-0
Synonyms: HBC 530
HBC (HBC 530) is a GFP fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC has a low fluorescence background, and when combined with Pepper (RNA aptamer), HBC forms a tight complex and activates and emits bright fluorescence (Kd of ~3.5 nM). HBC emission peaks vary in different complexes and covers the spectrum from cyan to red. HBC can be used in the live cell imaging of RNA (Em/Ex = 530/485 nm) .
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4
IR-783
IR-783
0 Images
4 Cited Publications
Cat. No.: HY-139109
CAS No.: 115970-66-6
Purity:  99.87%
Synonyms: ADS 780WS
IR-783 (ADS 780WS) is a heptamethine cyanine dye. IR-783 induces Mitochondrial membrane potential loss, ATP depletion, mitochondrial permeability transition pore opening, Cytochrome c release and Apoptosis in breast cancer cells. IR-783 promotes the translocation of Drp1 from the cytosol to mitochondria. IR-783 increases the expression of mitochondrial fission proteins such as MFF and Fission-1. IR-783 possesses imaging, cancer-targeting and anticancer properties. IR-783 exerts anticancer effects against breast cancer. IR-783 can be used in breast cancer-related research .
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3
HBmito Crimson
HBmito Crimson
0 Images
3 Cited Publications
Cat. No.: HY-D2346
HBmito Crimson is a deep red fluorescent probe (λex: 658 nm, λem: 678 nm) for the inner mitochondrial membrane. HBmito Crimson is a cell membrane-permeable probe with high selectivity for the mitochondrial inner membrane, suitable for specific fluorescence staining of the inner mitochondrial membrane in living cells. HBmito Crimson has high photostability and brightness, suitable for long-term dynamic fluorescence imaging.
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3
Cyanine5 DBCO hexafluorophosphate
Cyanine5 DBCO hexafluorophosphate
0 Images
3 Cited Publications
Cat. No.: HY-D1583
CAS No.: 2360411-64-7
Synonyms: DBCO-Cy5 hexafluorophosphate; Cyanine5 dibenzocyclooctyne hexafluorophosphate
Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
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3
SB-674042
SB-674042
0 Images
3 Cited Publications
Cat. No.: HY-10898
CAS No.: 483313-22-0
Purity:  99.93%
Target:  

Orexin Receptor (OX Receptor)

Research Areas:  

Neurological Disease Endocrinology

SB-674042 is a potent and selective non-peptide orexin OX1 receptor antagonist (Kd=5.03 nM), exhibits 100-fold selectivity for OX1 over OX2 receptors with IC50 values of 3.76 nM and 531 nM, respectively .
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2
Mito-TRFS
Mito-TRFS
0 Images
2 Cited Publications
Cat. No.: HY-D1250
CAS No.: 1859102-62-7
Mito-TRFS, the first off-on probe, is used to image the mitochondrial thioredoxin reductase (TrxR2) in live cells .
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2
Fast-TRFS
Fast-TRFS
0 Images
2 Cited Publications
Cat. No.: HY-D1252
CAS No.: 2966536-18-3
Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells .
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2
LPd peroxida probe-1
LPd peroxida probe-1
0 Images
2 Cited Publications
Cat. No.: HY-D1412
CAS No.: 1448846-35-2
LPd peroxida probe-1, a marker of ferroptosis, is a useful fluorescent probe for investigating the roles of lipid peroxidation in a variety of cell pathophysiologies. LPd peroxida probe-1 reduces lipid hydroperoxides to lipid alcohols and is used for imaging lipid hydroperoxides in living cells .
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2
EtS-DMAB
EtS-DMAB
0 Images
2 Cited Publications
Cat. No.: HY-D1265
CAS No.: 2929446-76-2
Synonyms: HClO-green
EtS-DMAB (HClO-green) is a fluorescent probe, which can selectively detect hypochlorous acid (HOCl) (λex=440 nm, λem=610 nm). EtS-DMAB is applied to image exogenous and endogenous HOCl in live cells .
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2
HKSOX-1 (5/6-mixture)
HKSOX-1 (5/6-mixture)
0 Images
2 Cited Publications
Cat. No.: HY-130015
Purity:  98.99%
HKSOX-1 (5/6-mixture) is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 (5/6-mixture) exhibits excellent selectivity and sensitivity towards superoxide anion radical (Ex/Em = 509/534 nm) .
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2
PM-1
PM-1
0 Images
2 Cited Publications
Cat. No.: HY-156404
CAS No.: 1449483-78-6
Purity:  99.04%
PM-1, a derivative of Thioflavin-T (ThT; HY-D0218), is a small but highly specific plasma membrane (PM) fluorescent dye for specific and long-time membrane imaging of living and fixed cells. PM-1 is embedded directly into the cell membrane and exhibits a very long retention time on the plasma membrane with a half-life of approximately 15 h. PM-1 can be used in combination with protein labeling probes to study ectodomain shedding and endocytosis processes of cell surface proteins .
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2
Tetraxetan
Tetraxetan
0 Images
2 Cited Publications
Cat. No.: HY-W053583
CAS No.: 60239-18-1
Synonyms: DOTA
Tetraxetan (DOTA) is a macrocyclic chelating agent. Tetraxetan can form stable coordination complexes with a variety of metal ions (e.g., 68Ga, 111In, 177Lu). Tetraxetan can be conjugated with targeting molecules (e.g., RGD peptide, folic acid) to enable the complex to target specific biomolecules or cells. Tetraxetan can be used for imaging studies of tumors, including melanoma and folate receptor-positive tumors (e.g., cervical cancer) .
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2
2-Deoxy-2-fluoro-D-glucose
2-Deoxy-2-fluoro-D-glucose
0 Images
2 Cited Publications
Cat. No.: HY-141637
CAS No.: 29702-43-0
Purity:  99.89%
Synonyms: 2-Fluoro-2-deoxy-D-glucose; 2-Deoxy-2-fluoro-D-glucopyranose; Fluorodeoxyglucose
2-Deoxy-2-fluoro-D-glucose (2-Fluoro-2-deoxy-D-glucose) is a glucose analog that can be absorbed by cells. 2-Deoxy-2-fluoro-D-glucose is capable of being labelled with 18F for positron emission tomography (PET) imaging. 18F-2-Deoxy-2-fluoro-D-glucose can be used to detect breast cancer and gastric cancer .
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1
DFHO
DFHO
0 Images
1 Cited Publications
Cat. No.: HY-136277
CAS No.: 1420815-34-4
Purity:  99.83%
DFHO is a fluorogenic ligand of Corn fluorogenic aptamer. The RNA aptamer, Corn binds DFHO with a Kd value of 70 nM and converts it to a fluorescent form, enabling RNA imaging in cells .
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