84 Results for "

cyclooxygenase 2 (COX2)

" in MedChemExpress (MCE) Product Catalog:
Products (84)

84 Results for "cyclooxygenase 2 (COX2)" in MCE Product Catalog:

  • Targets Recommended:
76
76 Publications Verification
Cat. No.: HY-66005
CAS No.: 103-90-2
Synonyms: Paracetamol; 4-Acetamidophenol; 4'-Hydroxyacetanilide
Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. . Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor . Acetaminophen induces ferroptosis and leads to acute liver injury in mice model .
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21
21 Cited Publications
Cat. No.: HY-13913
CAS No.: 123653-11-2
Purity:  99.71%
Target:  

COX

Research Areas:  

Inflammation/Immunology Cancer

NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM.
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19
19 Cited Publications
Cat. No.: HY-N0523
CAS No.: 149-91-7
Synonyms: 3,4,5-Trihydroxybenzoic acid
Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .
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19
19 Cited Publications
Cat. No.: HY-N0523A
CAS No.: 5995-86-8
Synonyms: 3,4,5-Trihydroxybenzoic acid hydrate
Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .
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16
16 Cited Publications
Cat. No.: HY-B0167
CAS No.: 69-72-7
Synonyms: 2-Hydroxybenzoic acid
Salicylic acid (2-Hydroxybenzoic acid) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation. Salicylic acid has blood-brain barrier permeability .
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16
16 Cited Publications
Cat. No.: HY-B0167A
CAS No.: 54-21-7
Synonyms: Salicylic acid sodium salt; 2-Hydroxybenzoic acid sodium salt
Sodium Salicylate (Salicylic acid sodium salt) inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation . Sodium Salicylate is also a S6K inhibitor.Sodium Salicylate is a NF-κB inhibitor that decreases inflammatory gene expression and improves repair in aged muscle .
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4
4 Cited Publications
Cat. No.: HY-N6966
CAS No.: 102-37-4
Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin .
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4
4 Cited Publications
Cat. No.: HY-P80091
Synonyms: PTGS2; COX 2; COX2; COX-2; cyclooxygenase; cyclooxygenase2; cyclooxygenase-2; hCox 2; PGG/HS; PGH synthase 2; PGHS 2; PGHS2; PHS 2; PHS II; PHS2 ; Prostaglandin endoperoxide synthase 2; Prostaglandin G/H synthase 2 precursor; Prostaglandin G/H synthase and cyclooxygenase; Prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; TIS10II; PGH2_HUMAN.

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P

Reactivity:  

Human, Mouse, Rat

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3
3 Cited Publications
Cat. No.: HY-P80090
Synonyms: COX2, PTGS2, Prostaglandin G/H synthase 2, cyclooxygenase-2, PHS II, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, COX-2, PGH synthase 2, PGHS-2

Host:  

Mouse

Application:  

WB, IHC-P, FC

Reactivity:  

Human, Mouse, Rat

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2
2 Cited Publications
Cat. No.: HY-N0632
CAS No.: 65497-07-6
Esculentoside A (EsA), a kind of triterpene saponin isolated from roots of Phytolacca esculenta . Esculentoside A (EsA) possesses anti-inflammatory activity in acute and chronic experimental models , has selective inhibitory activity towards cyclooxygenase-2 (COX-2) . Esculentoside A (EsA) suppresses inflammatory responses in LPS-induced acute lung injury (ALI) through inhibition of the nuclear factor kappa B (NF-ΚB) and mitogen activated protein kinase (MAPK) signaling pathways .
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2
2 Cited Publications
Cat. No.: HY-P74222
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PTGS2; cyclooxygenase-2; Prostaglandin-Endoperoxide Synthase 2; PGH Synthase 2; Prostaglandin G/H Synthase 2; PGHS-2; COX2; Prostaglandin-Endoperoxidase Synthase 2; Prostaglandin H2 Synthase 2; cyclooxygenase 2b; PHS II; GRIPGHS; COX-2; PGG/HS; Prostaglan
Species:  
Human
Source:  
Sf9 insect cells
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1
1 Cited Publications
Cat. No.: HY-B0167S
CAS No.: 285979-87-5
Synonyms: 2-Hydroxybenzoic acid-d6
Salicylic acid-d6 is a deuterium labeled Salicylic acid (HY-B0167). Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation .
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1
1 Cited Publications
Cat. No.: HY-66005R
CAS No.: 103-90-2
Synonyms: Paracetamol (Standard); 4-Acetamidophenol (Standard); 4'-Hydroxyacetanilide (Standard)
Acetaminophen (Standard) is the analytical standard of Acetaminophen. This product is intended for research and analytical applications. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent . Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .
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1
1 Cited Publications
Cat. No.: HY-113083
CAS No.: 16110-10-4
Purity:  ≥99.0%
Synonyms: APAP-glu
Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen (HY-66005) . Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .
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1
1 Cited Publications
Cat. No.: HY-N0074
CAS No.: 26091-79-2
Byakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory agent on airway inflammation .
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Cat. No.: HY-66005S
CAS No.: 64315-36-2
Synonyms: Paracetamol-d4; 4-Acetamidophenol-d4; 4'-Hydroxyacetanilide-d4
Acetaminophen-d4 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent . Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .
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Cat. No.: HY-N6084
CAS No.: 26472-41-3
Synonyms: α-Lupulic acid
Humulone (α-Lupulic acid), a prenylated phloroglucinol derivative, is a potent cyclooxygenase-2 (COX-2) inhibitor. Humulone acts as a positive modulator of GABAA receptor at low micromolar concentrations. Humulone is an inhibitor of bone resorption. Humulone possesses antioxidant, anti-angiogenic and apoptosis-inducing properties .
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Cat. No.: HY-107260
CAS No.: 98665-16-8
Purity:  99.78%
Synonyms: Lucidenic acid D2
Lucidenic acid D is a highly oxidized triterpenoid with anti-inflammatory and antiviral activities. Lucidenic acid D attenuates lipopolysaccharide-induced release of proinflammatory cytokines and nitric oxide, reduces the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), and inhibits skin inflammation. Lucidenic acid D suppresses 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced expression of Epstein-Barr virus (EBV) early antigen and maintains the viability of Raji cells. Lucidenic acid D can be used in studies of cancer chemoprevention .
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Cat. No.: HY-114200
CAS No.: 395683-14-4
Purity:  99.48%
Synonyms: BAP-909
Target:  

COX

Research Areas:  

Inflammation/Immunology

Imrecoxib (BAP-909) is a novel and selective cyclooxygenase 2 (COX-2) inhibitor with an IC50 value of 18 nM, it also inhibits COX1- activity with an IC50 value of 115 nM. Imrecoxib (BAP-909) has anti-inflammatory effect .
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Cat. No.: HY-N0523S
CAS No.: 294660-92-7
Synonyms: 3,4,5-Trihydroxybenzoic acid-d2
Gallic acid-d2 is the deuterium labeled Gallic acid . Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2) . Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities .
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