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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
518 Results for "
derived peptides
" in MedChemExpress (MCE) Product Catalog:
Products (518)
518 Results for "derived peptides" in MCE Product Catalog:
46
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N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC50 value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides .
16
16 Cited Publications
Cat. No.: HY-P0239
CAS No.: 92000-76-5
Category:
Natural Products Microorganisms Endogenous metabolite Disease Research Fields Inflammation/Immunology
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16
16 Cited Publications
Cat. No.: HY-P0239A
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14
14 Cited Publications
Synonyms: Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine
Target:
Liposome Endogenous Metabolite ACSL Family Amino acid Transporter Ferroptosis Glutathione Peroxidase
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DOPE (Dioleoylphosphatidylethanolamine; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine) is an orally active inhibitor of ferroptosis with anti-inflammatory and intestinal barrier maintenance activities. DOPE regulates the expression of ACSL4, SLC7A11 and GPX4 to restore the redox system balance, thereby reducing the levels of lipid peroxides, iron ions and intestinal inflammatory factors (IL-1β and IL-6). DOPE promotes the migration and proliferation of intestinal epithelial cells and increases the level of tight junction proteins; it also destabilizes endosomal membranes, mediates the conjugation of RVG peptides with mesenchymal stem cell-derived exosomes to enhance brain targeting. DOPE can be applied to research related to neonatal necrotizing enterocolitis and Alzheimer's disease .
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7 Cited Publications
Cat. No.: HY-P2260
CAS No.: 1423821-88-8
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6 Cited Publications
Cat. No.: HY-P1222
CAS No.: 154947-66-7
6
6 Cited Publications
Cat. No.: HY-P1222B
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6
6 Cited Publications
Cat. No.: HY-P1222A
5
5 Cited Publications
Cat. No.: HY-P2136
CAS No.: 878009-24-6
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5
5 Cited Publications
Cat. No.: HY-P1136
CAS No.: 1507930-57-5
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5
5 Cited Publications
Cat. No.: HY-P1122
CAS No.: 83602-39-5
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5
5 Cited Publications
Cat. No.: HY-P1136A
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4
4 Cited Publications
Cat. No.: HY-P3970A
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4
Category:
Monophenols Simple Phenylpropanols Phenols Dicerothamnus rhinocerotis Phenylpropanoids Plants Umbelliferae
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3
3 Cited Publications
Cat. No.: HY-P1237
CAS No.: 127869-51-6
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Cardiovascular Disease Neurological Disease Metabolic Disease
3
3 Cited Publications
Cat. No.: HY-P1237A
CAS No.: 1966153-17-2
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease
3
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3
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3
3 Cited Publications
Cat. No.: HY-P1832A
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
