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Results for "

fibrinogen

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Amyloid-β (2) AP-1 (1) Autophagy (2) Bacterial (3) Biochemical Assay Reagents (5) Cadherin (1) Cholinesterase (ChE) (1) Complement System (2) Cytochrome P450 (1) Drug Derivative (1) Drug Intermediate (1) Endogenous Metabolite (1) Epigenetic Reader Domain (1) Estrogen Receptor/ERR (1) Factor Xa (4) Factor XI (2) Fluorescent Dye (4) Glucocorticoid Receptor (2) Integrin (28) Interleukin Related (6) Isotope-Labeled Compounds (1) LAG-3 (1) LDLR (1) Lipase (1) Liposome (1) MMP (4) NF-κB (3) P-glycoprotein (1) PKC (2) Protease Activated Receptor (PAR) (1) Radionuclide-Drug Conjugates (RDCs) (1) Reference Standards (4) RSV (2) Ser/Thr Protease (1) TGF-beta/Smad (1) Thrombin (13) VEGFR (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (59) Endocrinology (1) Infection (4) Inflammation/Immunology (13) Metabolic Disease (6) Neurological Disease (6)
Oligonucleotides:	Cationic Lipids (1)

Inhibitors & Agonists

Screening Libraries

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Isotope-Labeled Compounds

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-125864

Fibrinogen (Bovine) 2 Publications Verification	Interleukin Related NF-κB	Inflammation/Immunology
Fibrinogen (Bovine) is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases .

HY-P1929

Bivalirudin Maximum Cited Publications 9 Publications Verification	Thrombin Interleukin Related RSV	Infection Cardiovascular Disease Inflammation/Immunology
Bivalirudin, a hirudin analog and anticoagulant, is a direct thrombin inhibitor. Bivalirudin inhibits thrombin-mediated fibrinogen cleavage, coagulation factor activation, and platelet activation by reversibly binding to thrombin. In addition, Bivalirudin also has certain effects of anti-virus, anti-inflammation, and vascular endothelial barrier function protection. Bivalirudin can be used for the research of thrombotic diseases and others .

HY-17369B

Tirofiban 5+ Cited Publications L700462; MK383	Integrin	Cardiovascular Disease
Tirofiban (L700462) is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits *fibrinogen* binding to this receptor and has antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area .

HY-17369

Tirofiban hydrochloride monohydrate 5+ Cited Publications L700462 hydrochloride monohydrate; MK383 hydrochloride monohydrate	Integrin	Cardiovascular Disease
Tirofiban (L700462) hydrochloride monohydrate is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits *fibrinogen* binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride monohydrate induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban hydrochloride monohydrate can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area .

HY-123275A

H-D-Phe-Pip-Arg-pNA hydrochloride 1 Publications Verification S-2238 hydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .

HY-123275B

H-D-Phe-Pip-Arg-pNA acetate 1 Publications Verification S-2238 acetate	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .

HY-P0074

GPRP 3 Publications Verification Gly-Pro-Arg-Pro; Pefa 6003	Thrombin	Cardiovascular Disease
GPRP (Gly-Pro-Arg-Pro; Pefa 6003) is a *fibrin* polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein Ⅱb/IIIa complex (glycoprotein IIb/IIIa receptor) . GPRP increases the level of free thrombin in activated platelet-rich plasma by reducing the adsorption of thrombin onto fibrin. GPRP inhibits platelet aggregation and prolongs the thrombin-initiated clotting time in plasma. GPRP is applicable for research related to thrombosis and thrombotic diseases .

HY-125864B

Murine Fibrinogen	MMP Cadherin	Cardiovascular Disease Neurological Disease
Murine Fibrinogen is a native fibrinogen derived from mouse plasma. Murine Fibrinogen acts as a cerebrovascular permeability enhancer. Murine Fibrinogen activates matrix metalloproteinase-9 (MMP-9), downregulates the expression of vascular endothelial cadherin (VE-cadherin), and upregulates the expression of plasmalemmal vesicle-associated protein-1 (PV-1). Murine Fibrinogen increases macromolecular leakage from pial veins, thereby disrupting the microvascular integrity of cerebral blood vessels. Murine Fibrinogen can be used in studies related to cerebrovascular dysfunction .

HY-15701

Leukadherin-1 5+ Cited Publications	Integrin Complement System	Inflammation/Immunology
Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC₅₀ of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling .

HY-P99505

Ziltivekimab COR-001; MEDI-5117; MEDI-5117; NN-6018; WBP-216	Interleukin Related LDLR	Inflammation/Immunology Endocrinology
Ziltivekimab (COR-001) is a fully human monoclonal antibody and also an IL-6 inhibitor. Ziltivekimab significantly reduces inflammatory biomarkers and Lipoprotein (a) in chronic kidney disease patients with systemic inflammation. Ziltivekimab does not increase pro-atherosclerotic lipid levels. Ziltivekimab is used in studies related to atherosclerotic thrombotic diseases and chronic kidney disease .

HY-114164G

Murine Thrombin 5+ Cited Publications	Thrombin Protease Activated Receptor (PAR) MMP VEGFR Epigenetic Reader Domain	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Murine Thrombin is a murine serine protease that plays a central role in blood coagulation. Murine Thrombin stimulates macrophages to polarize into a unique phenotype characterized by anti-inflammatory and pro-repair properties. Murine Thrombin activates PAR1, induces the production of MCP-1, MMP3 and VEGF in mouse intervertebral discs, and causes degradation of the cartilage matrix and destruction of intervertebral disc structure. Murine Thrombin activity increases significantly in paraoxon-induced status epilepticus .

HY-P0074A

GPRP acetate 3 Publications Verification Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate	Integrin	Cardiovascular Disease
GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .

HY-P5098

E(c(RGDfK))2	Integrin	Neurological Disease Cancer
E (c (RGDfK)) 2 is a αvβ3 integrin ligand and tumor-targeting agent. E (c (RGDfK)) 2 binds to αvβ3 integrin, mediates receptor-mediated endocytosis of conjugated payloads, and inhibits integrin-dependent cell adhesion to fibrinogen. E (c (RGDfK)) 2 inhibits the proliferation of cancer cells and endothelial cells. E (c (RGDfK)) 2 preferentially accumulates in orthotopic mouse breast tumors and human ovarian cancer xenograft tumors. E (c (RGDfK)) 2 can be used in research related to glioblastoma, lung cancer, breast adenocarcinoma and ovarian cancer .

HY-15664

Bivalirudin TFA Maximum Cited Publications 9 Publications Verification	Thrombin Interleukin Related RSV	Infection Cardiovascular Disease Inflammation/Immunology
Bivalirudin TFA, a hirudin analog and anticoagulant, is a direct thrombin inhibitor. Bivalirudin TFA inhibits thrombin-mediated fibrinogen cleavage, coagulation factor activation, and platelet activation by reversibly binding to thrombin. In addition, Bivalirudin TFA also has certain effects of anti-virus, anti-inflammation, and vascular endothelial barrier function protection. Bivalirudin TFA can be used for the research of thrombotic diseases and others .

HY-125864C

Porcine Fibrinogen	Biochemical Assay Reagents	Cardiovascular Disease
Porcine Fibrinogen is a coagulation protein, purified from porcine plasma with no plasminogen contained. Porcine Fibrinogen has excellent biocompatibility and does not induce aggregation of porcine platelets when in contact with porcine hepatocytes, aortic endothelial cells or hepatic sinusoidal endothelial cells. Porcine Fibrinogen is widely used in studies on the pathological mechanisms of cardiovascular diseases such as atherosclerosis and the development of related drugs .

HY-150229

306-N16B	Liposome	Cancer
306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .

HY-P1741

Fibrinogen-Binding Peptide 1 Publications Verification	Thrombin	Cardiovascular Disease
Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin .

HY-P0308

[Glu1]-Fibrinopeptide B	Drug Intermediate	Cardiovascular Disease
[Glu1]-Fibrinopeptide B is derived from fibrinopeptide B amino acid residues 1-14. Human fibrinopeptide B (hFpB), a thrombin-derived proteolytic cleavage product of the fibrinogen B beta-chain, to stimulate neutrophils (PMN), monocytes, and fibroblasts.

HY-N1400

(20R)-Ginsenoside Rh1	PKC	Cardiovascular Disease
(20R)-Ginsenoside Rh1 is the R-isomer of Ginsenoside Rh1 (HY-N0604), and it is found in red ginseng, ginseng, and other sources. (20R)-Ginsenoside Rh1 inhibits thrombin-induced conversion of fibrinogen to fibrin, exerting anticoagulant and antithrombotic effects .

HY-129056

Melagatran	Thrombin NF-κB AP-1	Cardiovascular Disease Neurological Disease
Melagatran is a reversible, selective, orally active direct inhibitor of thrombin with a K_i of 2 nM. Melagatran binds directly to the active site of thrombin, inhibiting thrombin-mediated conversion of fibrinogen to fibrin. Melagatran reduces the DNA binding activity of NF-κB and AP-1. Melagatran reduces fibrin deposition in organs, alleviates ischemic brain damage, and reduces the size of advanced atherosclerotic lesions. Melagatran can be used in the study of cardiovascular disease (coronary thrombosis, atherosclerosis) and ischemic brain damage .

HY-P3726

Lys-Gln-Ala-Gly-Asp-Val	Integrin	Inflammation/Immunology Cancer
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α_2bβ₃ integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs) .

HY-123275C

H-D-Phe-Pip-Arg-pNA dihydrochloride S-2238 dihydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .

HY-E70231

Thrombin-like enzyme	Others	Cardiovascular Disease
Thrombin-like enzyme is a proteolytic enzyme extraction of Agkistrodon halys venom. Thrombin-like enzyme can be used for degradation of fibrinogen. Thrombin-like enzyme can exacerbate myosin-induced EAM (experimental autoimmune myositis). Thrombin-like enzyme can be used for degradation of fibrinogen. Thrombin-like enzyme is commonly used for research of acute ischemic cerebrovascular disease, thromboangiitis obliterans, deep phlebitis and sudden deafness .

HY-P10045

Integrin signaling inhibitor, mP13	Integrin	Cardiovascular Disease
Integrin signaling inhibitor, mP13 is an inhibitor of integrin signaling. Integrin signaling inhibitor, mP13 inhibits inside-out and outside-in signaling, including fibrinogen binding, platelet adhesion, and clot retraction .

HY-107966A

Heparin calcium (MW 3600-5000) Nadroparin calcium (MW 3600-5000)	Thrombin Factor Xa Autophagy Bacterial	Cardiovascular Disease Cancer
Heparin (Nadroparin) calcium (MW 3600-5000) is an anticoagulant which binds reversibly to antithrombin III (ATIII) to form a heparin-antithrombin III complex. The complex binds to and irreversibly inactivates thrombin and other activated clotting factors IX, X, XI, and XII and prevents the transformation of fibrinogen to fibrin .

HY-125864A

Canine Fibrinogen	Biochemical Assay Reagents	Cardiovascular Disease
Canine Fibrinogen is a native fibrinogen from canine plasma .

HY-125864D

Rabbit Fibrinogen	Interleukin Related NF-κB	Cardiovascular Disease
Rabbit Fibrinogen is a native fibrinogen from rabbit plasma. Fibrinogen is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases .

HY-P1507

Fibrinogen Binding Inhibitor Peptide	Integrin	Cardiovascular Disease
Fibrinogen Binding Inhibitor Peptide is a dodecapeptide (HHLGGAKQAGDV, H12), which is a fibrinogen γ-chain carboxy-terminal sequence (γ400-411). Fibrinogen Binding Inhibitor Peptide is a specific binding site of the ligand for activated glycoprotein (GP) IIb/IIIa.

HY-NP167

Fibrinogen from rat plasma	Biochemical Assay Reagents	Others
Fibrinogen from rat plasma can be used to prepare growth factor solutions.

HY-123275

H-D-Phe-Pip-Arg-pNA S-2238	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .

HY-N0241

Rhodionin	Cholinesterase (ChE) Lipase Bacterial Cytochrome P450	Infection Metabolic Disease
Rhodionin is an orally active, multifunctional antivirulence and cytoprotective agent that targets and inhibits Lipase, sortase A (SrtA), CYP2D6 (IC₅₀=0.761 μM), AChE (IC₅₀=2.43-57.5 μM), and DPPH free radicals (IC₅₀=19.49 μM). Rhodionin is isolable from the roots of Rhodiola crenulata. Rhodionin reduces postprandial serum triglyceride levels in mice by inhibiting lipase activity. Rhodionin also binds directly to SrtA to inhibit its transpeptidase activity, thereby reducing the fibrinogen adhesion and surface protein A levels of MRSA, effectively inhibiting biofilm formation and protecting against MRSA-induced cell damage. Rhodionin improves the survival rate of infected mice without affecting MRSA growth, and finds wide application in studies related to hyperlipidemia, exogenous obesity, and pneumonia induced by methicillin-resistant Staphylococcus aureus (MRSA) .

HY-148400

Cetyl tranexamate hydrochloride TXC hydrochloride	Ser/Thr Protease Drug Derivative	Metabolic Disease
Cetyl tranexamate (TXC) hydrochloride is an ester derivative of Tranexamic acid (HY-B0149). Cetyl tranexamate hydrochloride is an inhibitor of fibrinogen activation and can reduce the production of fibrinogen in keratinocytes induced by ultraviolet rays or damage, indirectly inhibiting the melanin production pathway. Cetyl tranexamate hydrochloride also targets melanin (dark spots) and hemoglobin (red spots), reducing vascular dilation and pigmentation by inhibiting inflammatory mediators (such as prostaglandins, platelet activating factors). Cetyl tranexamate hydrochloride can be used as a cosmetic ingredient and is suitable for epidermal pigment disorders such as photoaging, post-inflammatory hyperpigmentation (PIH), and melasma .

HY-P1741A

Fibrinogen-Binding Peptide TFA 1 Publications Verification	Integrin	Cardiovascular Disease
Fibrinogen-Binding Peptide TFA (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide TFA binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin .

HY-P3537

AGDV	Amino Acid Derivatives	Cardiovascular Disease
AGDV is the γ chain of fibrinogen. AGDV is critical for platelet aggregation .

HY-121815

TDI-2760	Amyloid-β	Neurological Disease
TDI-2760 is an Aβ aggregation inhibitor with an IC₅₀ of 1.67 μM. TDI-2760 can inhibit the Aβ-fibrinogen interaction and Aβ aggregation, and also modulate the contact system activation induced by Aβ42. TDI-2760 can be used in research related to vascular abnormalities and Aβ aggregation in Alzheimer's disease .

HY-P1493

Fibrinopeptide B, human FPB,human	Thrombin	Inflammation/Immunology
Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.

HY-120694

ML165 RUC-2	Integrin	Cardiovascular Disease
ML165 (RUC-2) is an aIIbb3 receptor antagonist. ML165 has orthosteric inhibition effect at the RGD binding domain. ML165 inhibits platelet adhesion to fibrinogen, and inhibits platelet aggregation (IC₅₀: 96 nM) .

HY-114164H

Human α-Thrombin (Lyophilized) 5+ Cited Publications	Thrombin	Cardiovascular Disease
Human α-thrombin is a multifunctional serine protease that plays a pivotal role in the coagulation pathway. Human α-thrombin cleaves fibrinogen and converts it into fibrin. Human α-thrombin can stimulate platelet activation and stabilize fibrin polymers .

HY-107966

Heparin calcium (MW 15000-19000) Nadroparin calcium (MW 15000-19000)	Thrombin Factor Xa Autophagy Bacterial	Cardiovascular Disease Cancer
Heparin calcium (MW 15000-19000) is an anticoagulant which binds reversibly to antithrombin III (ATIII) to form a heparin-antithrombin III complex. The complex binds to and irreversibly inactivates thrombin and other activated clotting factors IX, X, XI, and XII and prevents the transformation of fibrinogen to fibrin .

HY-117464

CM-352	MMP	Cardiovascular Disease
CM-352 (compound 5) is an inhibitor of matrix metalloproteinases (MMPs) (MMP-3: IC₅₀=15 nM; MMP-10: IC₅₀=12 nM). CM-352 has significant antifibrinolytic activity (EC₅₀=0.7 nM) and can significantly prolong blood coagulation time. CM-352 can be used in anti-bleeding research .

HY-P991211

Bemiltenase alfa STSP-0601	Factor XI	Cardiovascular Disease
Bemiltenase alfa is a hemostatic agent targeting coagulation factor X (FX). Bemiltenase alfa activates FX and promotes the conversion of prothrombin to thrombin, and thrombin can further transform fibrinogen into fibrin, forming a stable blood clot, thus exerting hemostatic activity. Bemiltenase alfa is promising for research of bleeding symptoms with hemophilia .

HY-17369A

Tirofiban hydrochloride L700462 hydrochloride; MK383 hydrochloride	Integrin	Cardiovascular Disease
Tirofiban (L700462) hydrochloride is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits *fibrinogen* binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban hydrochloride can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area .

HY-17369BR

Tirofiban (Standard) L700462 (Standard); MK383 (Standard)	Reference Standards Integrin	Cardiovascular Disease
Tirofiban (Standard) is the analytical standard of Tirofiban. This product is intended for research and analytical applications. Tirofiban (L700462) is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits *fibrinogen* binding to this receptor and has antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area .

HY-172316

BAY 3389934	Factor Xa	Cardiovascular Disease
BAY 3389934 is a selective dual inhibitor of factor IIa and factor Xa, with an IC₅₀ of 4.9 nM for factor IIa and an IC₅₀ of 0.66 nM for factor Xa. BAY 3389934 directly inhibits the activities of factor IIa and factor Xa and regulates the common coagulation pathway. BAY 3389934 exhibits anticoagulant and organ-protective effects. BAY 3389934 can be used in the research of sepsis and coagulopathy .

HY-P5767

Fibrinogen γ-chain (117-133)	Integrin	Cardiovascular Disease
Fibrinogen γ-chain (117-133) is a selective intercellular adhesion molecule-1 (ICAM-1) inhibitor (IC₅₀≈20-40 μg/mL). Fibrinogen γ-chain (117-133) blocks fibrinogen-mediated monocyte-endothelial adhesion. Fibrinogen γ-chain (117-133) is promising for research of thrombo-inflammatory diseases (e.g., atherosclerosis, organ transplant rejection) .

HY-19275

FR-158999	Integrin	Cardiovascular Disease
FR-158999 is a potent orally active *fibrinogen* inhibitor. FR-158999 exhibits potent anti-platelet activities with a pIC₅₀ of 7.50. FR-158999 can be used for antithrombotic research .

HY-117824

L-703014	Integrin	Others
L-703014 is a fibrinogen receptor antagonist, with the IC₅₀ of 94 nM, that acts as a novel parenteral and potential oral antithrombotic agent .

HY-106932

L-734217	Integrin	Cardiovascular Disease
L-734217 is an orally active and potent fibrinogen receptor antagonist and an antithrombotic agent. L-734217 is excreted largely by the renal route and partly into the bile in dogs. L-734217 is promising for research of thrombotic disorders .

HY-10315

Elarofiban RWJ-53308	Integrin	Cardiovascular Disease
Elarofiban (RWJ-53308) is a nonpeptide, orally active antagonist for fibrinogen receptor α_IIbβ₃ (GPIIb/IIIa), with an IC₅₀ of 0.15 nM. Elarofiban has the potential for platelet mediated thrombotic disorders research .

HY-149833

ERRγ inverse agonist 2	Estrogen Receptor/ERR	Infection Metabolic Disease
ERRγ inverse agonist 2 (compound 19) is a potent and selective ERRγ inverse agonist with a K_d value of 6.5 μM. ERRγ inverse agonist 2 inhibits the expression of hepcidin, fibrinogen and gluconeogenic genes. ERRγ inverse agonist 2 has antimicrobial, anti-coagulant and antidiabetic activities .

Cat. No.	Product Name

HY-L136

Coagulation and Anti-coagulation Compound Library

1,437 compounds

Coagulation, also known as clotting, is the process in which blood changes from a liquid to a solid gel to form a blood clot. Thrombin, which is accurately and evenly generated in the injured part of blood vessels, is a key effector enzyme of the blood coagulation system and participates in many important biological processes, such as platelet activation, fibrinogen conversion to fibrin network, coagulation feedback amplification, etc. At the same time, to avoid the accidental formation of thrombus in the body, there is also an anticoagulant mechanism that inhibits blood coagulation.

Normal coagulation mechanism represents a balance between the pro-coagulant pathway in the injured site and anti-coagulant pathway beyond it. The blood coagulation system may be out of balance during the perioperative period or critical illness, which may lead to thrombosis or excessive bleeding. Therefore, the physiological study of coagulation balance is an important basis for clinical diagnosis and treatment of the abnormal coagulation process.

MCE supplies a unique collection of 1,437 compounds targeting key proteins in coagulation and anti-coagulation system. MCE Coagulation and Anti-coagulation Compound Library is a useful tool for study the mechanism of coagulation and anticoagulation.

Cat. No.	Product Name	Type

HY-125864

Fibrinogen (Bovine)

2 Publications Verification

Biochemical Assay Reagents

Fibrinogen (Bovine) is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases .

HY-150229

306-N16B

Biochemical Assay Reagents

306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .

HY-107966A

Heparin calcium (MW 3600-5000) Nadroparin calcium (MW 3600-5000)	Biochemical Assay Reagents
Heparin (Nadroparin) calcium (MW 3600-5000) is an anticoagulant which binds reversibly to antithrombin III (ATIII) to form a heparin-antithrombin III complex. The complex binds to and irreversibly inactivates thrombin and other activated clotting factors IX, X, XI, and XII and prevents the transformation of fibrinogen to fibrin .

HY-NP167

Fibrinogen from rat plasma	Biochemical Assay Reagents
Fibrinogen from rat plasma can be used to prepare growth factor solutions.

HY-107966

Heparin calcium (MW 15000-19000) Nadroparin calcium (MW 15000-19000)	Biochemical Assay Reagents
Heparin calcium (MW 15000-19000) is an anticoagulant which binds reversibly to antithrombin III (ATIII) to form a heparin-antithrombin III complex. The complex binds to and irreversibly inactivates thrombin and other activated clotting factors IX, X, XI, and XII and prevents the transformation of fibrinogen to fibrin .

HY-NP185

Chicken Tenascin,suitable for cell culture	Biochemical Assay Reagents
Chicken Tenascin,suitable for cell culture is a glycoprotein that forms disulfide-linked hexamers. Chicken Tenascin,suitable for cell culture is composed of repetitive domains, including EGF-like repeats, fibronectin type III repeats, and a region homologous to fibrinogen. Chicken Tenascin,suitable for cell culture can be used for cell culture .

Cat. No.	Product Name	Target	Research Area

HY-P1929

Bivalirudin Maximum Cited Publications 9 Publications Verification	Thrombin Interleukin Related RSV	Infection Cardiovascular Disease Inflammation/Immunology
Bivalirudin, a hirudin analog and anticoagulant, is a direct thrombin inhibitor. Bivalirudin inhibits thrombin-mediated fibrinogen cleavage, coagulation factor activation, and platelet activation by reversibly binding to thrombin. In addition, Bivalirudin also has certain effects of anti-virus, anti-inflammation, and vascular endothelial barrier function protection. Bivalirudin can be used for the research of thrombotic diseases and others .

HY-123275A

H-D-Phe-Pip-Arg-pNA hydrochloride 1 Publications Verification S-2238 hydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .

HY-123275B

H-D-Phe-Pip-Arg-pNA acetate 1 Publications Verification S-2238 acetate	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .

HY-P0074

GPRP 3 Publications Verification Gly-Pro-Arg-Pro; Pefa 6003	Thrombin	Cardiovascular Disease
GPRP (Gly-Pro-Arg-Pro; Pefa 6003) is a *fibrin* polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein Ⅱb/IIIa complex (glycoprotein IIb/IIIa receptor) . GPRP increases the level of free thrombin in activated platelet-rich plasma by reducing the adsorption of thrombin onto fibrin. GPRP inhibits platelet aggregation and prolongs the thrombin-initiated clotting time in plasma. GPRP is applicable for research related to thrombosis and thrombotic diseases .

HY-P0074A

GPRP acetate 3 Publications Verification Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate	Integrin	Cardiovascular Disease
GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) .

HY-P5098

E(c(RGDfK))2	Integrin	Neurological Disease Cancer
E (c (RGDfK)) 2 is a αvβ3 integrin ligand and tumor-targeting agent. E (c (RGDfK)) 2 binds to αvβ3 integrin, mediates receptor-mediated endocytosis of conjugated payloads, and inhibits integrin-dependent cell adhesion to fibrinogen. E (c (RGDfK)) 2 inhibits the proliferation of cancer cells and endothelial cells. E (c (RGDfK)) 2 preferentially accumulates in orthotopic mouse breast tumors and human ovarian cancer xenograft tumors. E (c (RGDfK)) 2 can be used in research related to glioblastoma, lung cancer, breast adenocarcinoma and ovarian cancer .

HY-15664

Bivalirudin TFA Maximum Cited Publications 9 Publications Verification	Thrombin Interleukin Related RSV	Infection Cardiovascular Disease Inflammation/Immunology
Bivalirudin TFA, a hirudin analog and anticoagulant, is a direct thrombin inhibitor. Bivalirudin TFA inhibits thrombin-mediated fibrinogen cleavage, coagulation factor activation, and platelet activation by reversibly binding to thrombin. In addition, Bivalirudin TFA also has certain effects of anti-virus, anti-inflammation, and vascular endothelial barrier function protection. Bivalirudin TFA can be used for the research of thrombotic diseases and others .

HY-P1741

Fibrinogen-Binding Peptide 1 Publications Verification	Thrombin	Cardiovascular Disease
Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin .

HY-P0308

[Glu1]-Fibrinopeptide B	Drug Intermediate	Cardiovascular Disease
[Glu1]-Fibrinopeptide B is derived from fibrinopeptide B amino acid residues 1-14. Human fibrinopeptide B (hFpB), a thrombin-derived proteolytic cleavage product of the fibrinogen B beta-chain, to stimulate neutrophils (PMN), monocytes, and fibroblasts.

HY-P3726

Lys-Gln-Ala-Gly-Asp-Val	Integrin	Inflammation/Immunology Cancer
Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α_2bβ₃ integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs) .

HY-123275C

H-D-Phe-Pip-Arg-pNA dihydrochloride S-2238 dihydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .

HY-P10045

Integrin signaling inhibitor, mP13	Integrin	Cardiovascular Disease
Integrin signaling inhibitor, mP13 is an inhibitor of integrin signaling. Integrin signaling inhibitor, mP13 inhibits inside-out and outside-in signaling, including fibrinogen binding, platelet adhesion, and clot retraction .

HY-P1507

Fibrinogen Binding Inhibitor Peptide	Integrin	Cardiovascular Disease
Fibrinogen Binding Inhibitor Peptide is a dodecapeptide (HHLGGAKQAGDV, H12), which is a fibrinogen γ-chain carboxy-terminal sequence (γ400-411). Fibrinogen Binding Inhibitor Peptide is a specific binding site of the ligand for activated glycoprotein (GP) IIb/IIIa.

HY-P5121A

*γ-Fibrinogen* 377-395 TFA**	Peptides	Cardiovascular Disease
γ-Fibrinogen377-395 TFA is a fibrinogen-derived inhibitory peptide, as well as fibrinogen epitope. γ-Fibrinogen377-395 TFA blocks microglia activation and inhibits fibrin-Mac-1 interactions in vitro, and suppresses experimental autoimmune encephalomyelitis (EAE) in mice in vivo. γ-Fibrinogen377-395 TFA can be used for research in multiple sclerosis (MS), and other neuroinflammatory diseases associated with blood-brain barrier disruption and microglia activation .

HY-P5991

K-Casein (106-116),bovine	Peptides	Cardiovascular Disease
K-Casein (106-116),bovine is a peptide that inhibits platelet aggregation and fibrinogen binding, plays an important role in atherosclerosis .

HY-123275

H-D-Phe-Pip-Arg-pNA S-2238	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .

HY-P1741A

Fibrinogen-Binding Peptide TFA 1 Publications Verification	Integrin	Cardiovascular Disease
Fibrinogen-Binding Peptide TFA (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide TFA binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin .

HY-P0314A

Arg-Gly-Asp-Cys TFA	Peptides	Cardiovascular Disease
Arg-Gly-Asp-Cys TFA is the binding motif of fibronectin to cell adhesion molecules. Arg-Gly-Asp-Cys TFA can inhibit platelet aggregation and fibrinogen binding .

HY-P1538A

Fibrinopeptide A, human TFA Human fibrinopeptide A TFA	Peptides	Cardiovascular Disease
Fibrinopeptide A, human TFA is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH₂-termini of the Aα chain .

HY-P5121B

*γ-Fibrinogen* 377-395 scrambled TFA**	Peptides	Cardiovascular Disease
γ-Fibrinogen 377-395 scrambled TFA is a control peptide that forms a structure similar to that of γ-Fibrinogen 377-395 TFA (HY-P5121A) but possesses a scrambled sequence in the target-binding region.

HY-P3531

Fibrinogen γ-chain (397-411)	Peptides	Others
Fibrinogen γ-chain (397-411), a esidues 397-411 of the γ chain of fibrinogen, is a site recognizing the platelet receptor, which is distinct from the site(s) involved in polymerization of fibrin monomers .

HY-P1493

Fibrinopeptide B, human FPB,human	Thrombin	Inflammation/Immunology
Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin.

HY-P0314

Arg-Gly-Asp-Cys	Peptides	Others
Arg-Gly-Asp-Cys is the binding motif of fibronectin to cell adhesion molecules, and can inhibit platelet aggregation and fibrinogen binding.

HY-P5121

*γ-Fibrinogen* 377-395**	Peptides	Cardiovascular Disease
γ-Fibrinogen377-395 is a fibrinogen-derived inhibitory peptide, as well as fibrinogen epitope. γ-Fibrinogen377-395 blocks microglia activation and inhibits fibrin-Mac-1 interactions in vitro, and suppresses experimental autoimmune encephalomyelitis (EAE) in mice in vivo. γ-Fibrinogen377-395 can be used for research in multiple sclerosis (MS), and other neuroinflammatory diseases associated with blood-brain barrier disruption and microglia activation .

HY-P5767

Fibrinogen γ-chain (117-133)	Integrin	Cardiovascular Disease
Fibrinogen γ-chain (117-133) is a selective intercellular adhesion molecule-1 (ICAM-1) inhibitor (IC₅₀≈20-40 μg/mL). Fibrinogen γ-chain (117-133) blocks fibrinogen-mediated monocyte-endothelial adhesion. Fibrinogen γ-chain (117-133) is promising for research of thrombo-inflammatory diseases (e.g., atherosclerosis, organ transplant rejection) .

HY-P1538

Fibrinopeptide A, human Human fibrinopeptide A	Peptides	Cardiovascular Disease
Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH₂-termini of the Aα chain.

HY-P1493A

Fibrinopeptide B, human TFA FPB,human TFA	Peptides	Inflammation/Immunology
Fibrinopeptide B, human TFA (FPB,human TFA), human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin .

HY-P4278

H-Gly-His-Arg-Pro-NH2	Peptides	Others
H-Gly-His-Arg-Pro-NH2 (GHRP-amide) is composed of L-prolinamide, glycine, L-histidine, L-arginine, and participates in the binding of desAB-NDSK to fibrinogen .

HY-P0038

MK-852 L-367073	Integrin	Cardiovascular Disease
MK-852 (L-367073) is an effective GPIIb/IIIa receptor antagonist. MK-852 can significantly inhibit the binding of fibrinogen to platelets in vitro. MK-852can be used for the study of thrombosis .

HY-P11416

Ac-RGDS-NH2	Integrin	Cardiovascular Disease
Ac-RGDS-NH2, a tetrapeptide, is an integrin antagonist. Ac-RGDS-NH2 competitively binds to the GPIIb/IIIa receptor (K_i = 4.2 μM), inhibiting the binding of fibrinogen to platelets and thereby effectively suppressing platelet aggregation. Ac-RGDS-NH2 can be used for research on thrombosis .

HY-P1711

L 366763	Peptides	Cardiovascular Disease
L 366763 is a potent peptide that acts as a fibrinogen receptor antagonist, preventing collagen-induced platelet aggregation and adhesion. L 366763 inhibits platelet deposition and maintains blood flow in a baboon thrombosis model, significantly prolonging bleeding time. L 366763 has antithrombotic efficacy, whereas recombinant LAPP does not have the same effect .

HY-176277S

Fibrinopeptide B, human-(Val-13C5,15N, Arg-13C6,15N4) TFA FPB,human-(Val-13C5,15N, Arg-13C6,15N4) TFA	Isotope-Labeled Compounds	Inflammation/Immunology
Fibrinopeptide B, human-(Val- ¹³C₅, ¹⁵N, Arg- ¹³C₆, ¹⁵₄) TFA is the ¹³C- and ¹⁵N-labeled Fibrinopeptide B, human (HY-P1493). Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin .

HY-P3335

SU015 DOTA-RGDfK dimer	Integrin Radionuclide-Drug Conjugates (RDCs)	Cardiovascular Disease Cancer
SU015 (DOTA-RGDfK dimer) is a Integrin α_vβ₅ and α_vβ₃ antagonist. SU015 exhibits comparable affinity for α_vβ₅ and α_vβ₃, with relatively higher potency and specificity compared to other integrins. SU015 inhibits α_vβ₃-mediated cell adhesion to fibrinogen, α_vβ₃-mediated adhesion of activated platelets to osteopontin, and α_vβ₅-mediated cell adhesion to vitronectin. SU015 shows potent inhibitory effects on FGF2-induced angiogenesis in the CAM model. SU015 carries a linker arm available for radioisotope conjugation, and acts as a target-specific radioreagent when labeled with ⁹⁰Y (i.e., RP697) or ¹⁷⁷Lu (i.e., RP688). SU015 can be used in studies related to tumor metastasis and tumors .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99505

Ziltivekimab COR-001; MEDI-5117; MEDI-5117; NN-6018; WBP-216	Interleukin Related LDLR	Inflammation/Immunology Endocrinology
Ziltivekimab (COR-001) is a fully human monoclonal antibody and also an IL-6 inhibitor. Ziltivekimab significantly reduces inflammatory biomarkers and Lipoprotein (a) in chronic kidney disease patients with systemic inflammation. Ziltivekimab does not increase pro-atherosclerotic lipid levels. Ziltivekimab is used in studies related to atherosclerotic thrombotic diseases and chronic kidney disease .

HY-P991211

Bemiltenase alfa STSP-0601	Factor XI	Cardiovascular Disease
Bemiltenase alfa is a hemostatic agent targeting coagulation factor X (FX). Bemiltenase alfa activates FX and promotes the conversion of prothrombin to thrombin, and thrombin can further transform fibrinogen into fibrin, forming a stable blood clot, thus exerting hemostatic activity. Bemiltenase alfa is promising for research of bleeding symptoms with hemophilia .

HY-P991213

Nonacog gamma Rixubis	Factor XI	Cardiovascular Disease
Nonacog gamma is a coagulation factor IX (FIX) supplement. Nonacog gamma activates coagulation factor X (FX), promotes the generation of thrombin, and then converts fibrinogen into fibrin, forming a stable blood clot to exert hemostatic activity. Nonacog gamma is promising for research of hemophilia B .

HY-P992092

Biciromab	Inhibitory Antibodies	Cardiovascular Disease
Biciromab is a anti-human monoclonal antibody targeting *FGB/Fibrinogen* beta chain** .

HY-P992461

SHR-1802	LAG-3	Cancer
SHR-1802 is a humanized anti-LAG-3 monoclonal antibody.SHR-1802 specifically binds to LAG-3 and inhibits its binding to major histocompatibility complex class II (MHC-II), fibrinogen-like protein 1 (FGL1), galectin-3, and liver sinusoidal endothelial cell lectin.SHR-1802 can be used for the research of advanced solid tumors .

Species:	Human (15) Rhesus Macaque (1) Rat (2) Mouse (5) Cynomolgus (5) Staphylococcus aureus (3)
Tag:	SUMO (1) His (19) Tag Free (3) Avi (8) GST (1) Flag (8) Fc (8)
Source:	HEK293 (21) Sf9 insect cells (3) P. pastoris (4) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P75772

	*FGG/Fibrinogen* gamma chain Protein, Human (P.pastoris)** 1 Publications Verification fibrinogen gamma chain; FGG; PRO2061	Human	P. pastoris
	FGG/fibrinogen gamma chain proteins polymerize together with FGA and FGB to form the fibrin matrix, which is essential for blood clot formation. In addition to coagulation, it aids in early wound repair, stabilizes lesions, and guides cell migration. FGG/Fibrinogen gamma chain Protein, Human (P.pastoris) is the recombinant human-derived FGG/Fibrinogen gamma chain protein, expressed by P. pastoris , with tag free.

HY-P702579

	*FGG/Fibrinogen* gamma chain Protein, Mouse (P.pastoris)** fibrinogen gamma chain; FGG; PRO2061	Mouse	P. pastoris
	FGG (fibrinogen gamma chain) proteins cooperate with FGA and FGB to form an insoluble fibrin matrix that is critical for hemostasis and wound repair. Although FGG is not required for thrombosis, it stabilizes lesions and guides cell migration during epithelialization. FGG/Fibrinogen gamma chain Protein, Mouse (P.pastoris, Tag Free) is the recombinant mouse-derived FGG/Fibrinogen gamma chain, expressed by P. pastoris, with tag-free. The total length of FGG/Fibrinogen gamma chain Protein, Mouse (P.pastoris, Tag Free) is 269 a.a..

HY-P72291

	Clumping factor B Protein, S. aureus (His, SUMO) fibrinogen receptor B; fibrinogen-binding protein B	Staphylococcus aureus	E. coli
	Clumping factor B (ClfB) is a cell surface-associated protein implicated in virulence, playing a crucial role in bacterial pathogenicity by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen. Its significance lies in inducing the formation of bacterial clumps, a mechanism that contributes to the pathogenicity and virulence of the bacteria. Clumping factor B Protein, S. aureus (His, SUMO) is the recombinant Staphylococcus aureus-derived Clumping factor B protein, expressed by E. coli , with N-6*His-SUMO labeled tag.

HY-P71829

	Clumping factor A Protein, S. aureus (P.pastoris, His) clfA; fibrinogen receptor A; fibrinogen-binding protein A	Staphylococcus aureus	P. pastoris
	Clumping factor A protein facilitates bacterial attachment to human fibrinogen gamma-chain, promoting the formation of bacterial clumps. It is a cell surface-associated protein and plays a role in bacterial virulence. Clumping factor A Protein, S. aureus (P.pastoris, His) is the recombinant Staphylococcus aureus-derived Clumping factor A protein, expressed by P. pastoris , with N-His labeled tag.

HY-P704614

	FGL2 Protein, Human (HEK293, His) Fibroleukin; pT49; FGL2; fibrinogen-like 2;	Human	HEK293
	FGL2 protein is involved in immune responses specific to mucosal tissues, regulating physiologic lymphocyte functions. It forms disulfide-linked homotetramers, indicating its quaternary structure. Studying how FGL2 influences lymphocyte functions and its homotetrameric organization can provide insights into its role in mucosal immunity and immune system regulation. FGL2 Protein, Human (HEK293, His) is the recombinant human-derived FGL2 protein, expressed by HEK293, with N-His labeled tag.

HY-P71581

	Clumping factor A Protein, S. aureus clfA; SAS0752; Clumping factor A; fibrinogen receptor A; fibrinogen-binding protein A	Staphylococcus aureus	E. coli
	Clustering factor A (ClfA) is a virulence-related cell surface-associated protein that plays a key role in bacterial pathogenicity. It promotes bacterial attachment exclusively to the gamma chain of human fibrinogen, demonstrating the specificity of its interaction with host proteins. Clumping factor A Protein, S. aureus is the recombinant Staphylococcus aureus-derived Clumping factor A protein, expressed by E. coli , with tag free.

HY-P701078

	FGL2 Protein, Human (HEK293, hFc-Flag) Fibroleukin; pT49; FGL2; fibrinogen-like 2;	Human	HEK293
	FGL2 protein is involved in immune responses specific to mucosal tissues, regulating physiologic lymphocyte functions. It forms disulfide-linked homotetramers, indicating its quaternary structure. Studying how FGL2 influences lymphocyte functions and its homotetrameric organization can provide insights into its role in mucosal immunity and immune system regulation. FGL2 Protein, Human (HEK293, hFc-Flag) is the recombinant human-derived FGL2 protein, expressed by HEK293 , with N-hFc, N-Flag labeled tag.

HY-P700990

	FGL2 Protein, Mouse (HEK293, His-Avi, Flag) 2 Publications Verification Fibroleukin; pT49; FGL2; fibrinogen-like 2;	Mouse	HEK293
	FGL2 is a key enzyme in the coagulation cascade and plays a key role in the conversion of prothrombin to thrombin, reflecting its important contribution to hemostasis and coagulation processes. Structurally, FGL2 forms homotetramers characterized by disulfide bonds that contribute to its functional integrity and catalytic activity in the complex process of thrombin generation. FGL2 Protein, Mouse (HEK293, His-Avi, Flag) is the recombinant mouse-derived FGL2 protein, expressed by HEK293 , with C-Avi, N-His, N-Flag labeled tag.

HY-P700721

	FGL2 Protein, Human (HEK293, His-Avi, Flag) Fibroleukin; pT49; FGL2; fibrinogen-like 2;	Human	HEK293
	FGL2 protein is involved in immune responses specific to mucosal tissues, regulating physiologic lymphocyte functions. It forms disulfide-linked homotetramers, indicating its quaternary structure. Studying how FGL2 influences lymphocyte functions and its homotetrameric organization can provide insights into its role in mucosal immunity and immune system regulation. FGL2 Protein, Human (HEK293, His-Avi, Flag) is the recombinant human-derived FGL2 protein, expressed by HEK293 , with C-Avi, N-His, N-Flag labeled tag.

HY-P701059

	FGL2 Protein, Cynomolgus (HEK293, His-Avi, Flag) Fibroleukin; pT49; FGL2; fibrinogen-like 2;	Cynomolgus	HEK293
	FGL2 is a key enzyme in the coagulation cascade and plays a key role in the conversion of prothrombin to thrombin, reflecting its important contribution to hemostasis and coagulation processes. Structurally, FGL2 forms homotetramers characterized by disulfide bonds that contribute to its functional integrity and catalytic activity in the complex process of thrombin generation. FGL2 Protein, Cynomolgus (HEK293, His-Avi, Flag) is the recombinant cynomolgus-derived FGL2 protein, expressed by HEK293 , with C-Avi, N-His, N-Flag labeled tag.

HY-P700987

	FGL2 Protein, Human (Biotinylated, HEK293, His-Avi, Flag) Fibroleukin; pT49; FGL2; fibrinogen-like 2;	Human	HEK293
	FGL2 protein is involved in immune responses specific to mucosal tissues, regulating physiologic lymphocyte functions. It forms disulfide-linked homotetramers, indicating its quaternary structure. Studying how FGL2 influences lymphocyte functions and its homotetrameric organization can provide insights into its role in mucosal immunity and immune system regulation. FGL2 Protein, Human (Biotinylated, HEK293, His-Avi, Flag) is the recombinant human-derived FGL2 protein, expressed by HEK293 , with C-Avi, N-His, N-Flag labeled tag.

HY-P700988

	FGL2 Protein, Mouse (Biotinylated, HEK293, His-Avi, Flag) Fibroleukin; pT49; FGL2; fibrinogen-like 2;	Mouse	HEK293
	FGL2 is a key enzyme in the coagulation cascade and plays a key role in the conversion of prothrombin to thrombin, reflecting its important contribution to hemostasis and coagulation processes. Structurally, FGL2 forms homotetramers characterized by disulfide bonds that contribute to its functional integrity and catalytic activity in the complex process of thrombin generation. FGL2 Protein, Mouse (Biotinylated, HEK293, His-Avi, Flag) is the recombinant mouse-derived FGL2 protein, expressed by HEK293 , with C-Avi, N-His, N-Flag labeled tag.

HY-P700989

	FGL2 Protein, Rat (Biotinylated, HEK293, His-Avi, Flag) Fibroleukin; pT49; FGL2; fibrinogen-like 2;	Rat	HEK293
	FGL2 is a key enzyme in the coagulation cascade and plays a key role in the conversion of prothrombin to thrombin, reflecting its important contribution to hemostasis and coagulation processes. Structurally, FGL2 forms homotetramers characterized by disulfide bonds that contribute to its functional integrity and catalytic activity in the complex process of thrombin generation. FGL2 Protein, Rat (Biotinylated, HEK293, His-Avi, Flag) is the recombinant rat-derived FGL2 protein, expressed by HEK293 , with C-Avi, N-His, N-Flag labeled tag.

HY-P701058

	FGL2 Protein, Cynomolgus (Biotinylated, HEK293, His-Avi, Flag) Fibroleukin; pT49; FGL2; fibrinogen-like 2;	Cynomolgus	HEK293
	FGL2 is a key enzyme in the coagulation cascade and plays a key role in the conversion of prothrombin to thrombin, reflecting its important contribution to hemostasis and coagulation processes. Structurally, FGL2 forms homotetramers characterized by disulfide bonds that contribute to its functional integrity and catalytic activity in the complex process of thrombin generation. FGL2 Protein, Cynomolgus (Biotinylated, HEK293, His-Avi, Flag) is the recombinant cynomolgus-derived FGL2 protein, expressed by HEK293 , with C-Avi, N-His, N-Flag labeled tag.

HY-P72642

	FGL1 Protein, Cynomolgus (HEK293, His) fibrinogen like 1; FGL1	Cynomolgus	HEK293
	Fibrinogen like 1 (FGL1) is a proliferation- and metabolism-related protein secreted by the liver. FGL1 is also upregulated in tumor tissues. FGL1 is a checkpoint ligand of lymphocyte activation gene 3 (LAG3). When binding to LAG3, FGL1 can inhibit T cell activation and proliferation. FGL1 can be used for research of immune checkpoint therapy. FGL1 plays a role in proliferation, metabolism, apoptosis, epithelial-to-mesenchymal transition, and immune infiltration. FGL1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived FGL1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76930

	Ficolin-1 Protein, Human (HEK293, His) Ficolin-1; Collagen/fibrinogen domain-containing protein 1; Ficolin-A; FCNM	Human	HEK293
	IFN-β protein is a recombinant protein that does not use any animal-derived components in its production. It is used in biomedical research and drug manufacturing as a therapeutic agent for a variety of diseases, including multiple sclerosis. Ficolin-1 Protein, Human (HEK293, His) is the recombinant human-derived Ficolin-1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P70740

	FGL1 Protein, Human (HEK293, mFc) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Human	HEK293
	FGL1 protein is the main ligand of LAG3 and can inhibit antigen-specific T cell activation, mediating the inhibitory function of LAG3 independently of MHC-II binding. FGL1 is secreted by liver cells and contributes to their growth. FGL1 Protein, Human (HEK293, mFc) is the recombinant human-derived FGL1 protein, expressed by HEK293 , with C-mFc labeled tag.

HY-P75188

	FGL1 Protein, Mouse (sf9, His) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Mouse	Sf9 insect cells
	FGL1 Protein, a potent immune suppressive molecule, inhibits antigen-specific T-cell activation as a major ligand for LAG3. It crucially contributes to LAG3-mediated T-cell inhibitory functions, independently of MHC class II. Secreted by hepatocytes, FGL1 also promotes their growth. The homodimeric form of the protein interacts with LAG3, specifically engaging with its Ig-like domains 1 and 2 through the Fibrinogen C-terminal domain. FGL1 Protein, Mouse (sf9, His) is the recombinant mouse-derived FGL1 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75189

	FGL1 Protein, Mouse (HEK293, hFc) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Mouse	HEK293
	The FGL1 protein has signaling receptor binding activity and negatively regulates T cell activation and immune response. It is involved in adipose tissue development, cholesterol metabolism, and response to stilbenoid. FGL1 is located in the extracellular region and is orthologous to the human FGL1 gene. It is primarily expressed in the liver at the E18 stage. FGL1 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived FGL1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77366

	FGL1 Protein, Cynomolgus (HEK293, Fc) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Cynomolgus	HEK293
	FGL1 is a specific hepatocyte mitogen, regulates the expression of proliferative factors, promoting liver regeneration and repairing liver injury. FGL1 inhibits T-cell activation by binding to LAG3. FGL1 promotes cell proliferation by activating the ERK/p-ERK pathway. FGL1 inhibits apoptosis of non-small cell lung cancer (NSCLC) cells by inhibiting PARP1/caspase 3 pathway. FGL1 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived FGL1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P70737A

	FGL1 Protein, Human (HEK293, His) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Human	HEK293
	FGL1 protein is the main ligand of LAG3 and can inhibit antigen-specific T cell activation, mediating the inhibitory function of LAG3 independently of MHC-II binding. FGL1 is secreted by liver cells and contributes to their growth. FGL1 Protein, Human (HEK293, His) is the recombinant human-derived FGL1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P704612

	FGL1 Protein, Human (HEK293, Fc) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Human	HEK293
	FGL1 protein is the main ligand of LAG3 and can inhibit antigen-specific T cell activation, mediating the inhibitory function of LAG3 independently of MHC-II binding. FGL1 is secreted by liver cells and contributes to their growth. FGL1 Protein, Human (HEK293, Fc) is the recombinant human-derived FGL1 protein, expressed by HEK293, with C-hFc labeled tag.

HY-P75771

	FGL1 Protein, Rat (sf9, His) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Rat	Sf9 insect cells
	The FGL1 protein is a key immunosuppressant that acts as the primary ligand of LAG3 to inhibit antigen-specific T cell activation. FGL1 is essential for the T cell suppressor function of LAG3, which is independent of MHC class II (MHC-II) binding. FGL1 is secreted by hepatocytes and actively promotes their growth. FGL1 Protein, Rat (sf9, His) is the recombinant rat-derived FGL1 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P77367

	FGL1 Protein, Cynomolgus (sf9, His) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Cynomolgus	Sf9 insect cells
	FGL1 is a specific hepatocyte mitogen, regulates the expression of proliferative factors, promoting liver regeneration and repairing liver injury. FGL1 inhibits T-cell activation by binding to LAG3. FGL1 promotes cell proliferation by activating the ERK/p-ERK pathway. FGL1 inhibits apoptosis of non-small cell lung cancer (NSCLC) cells by inhibiting PARP1/caspase 3 pathway. FGL1 Protein, Cynomolgus (sf9, His) is the recombinant cynomolgus-derived FGL1 protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P70737

	FGL1 Protein, Human (HEK293, His, solution) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Human	HEK293
	FGL1 protein is the main ligand of LAG3 and can inhibit antigen-specific T cell activation, mediating the inhibitory function of LAG3 independently of MHC-II binding. FGL1 is secreted by liver cells and contributes to their growth. FGL1 Protein, Human (HEK293, His, solution) is the recombinant human-derived FGL1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P700562

	ANGPTL4/Angiopoietin-related 4 Protein, Human (GST) Angiopoietin-like protein 4Hepatic fibrinogen/angiopoietin-related protein ; HFARP	Human	E. coli
	ANGPTL4 protein mediates lipoprotein lipase (LPL) inactivation, regulating triglyceride clearance and lipid metabolism. It also affects glucose homeostasis, insulin sensitivity, endothelial cell function, and angiogenesis. Cleaved ANGPTL4 is more active in LPL inactivation, highlighting its multifaceted role in metabolic and vascular regulation. ANGPTL4/Angiopoietin-related 4 Protein, Human (GST) is the recombinant human-derived ANGPTL4/Angiopoietin-related 4 protein, expressed by E. coli , with N-GST labeled tag.

HY-P77368

	Ficolin-1 Protein, Rhesus Macaque (HEK293, Fc) Collagen/fibrinogen domain-containing protein 1; Ficolin-A; M-ficolin; FCN1; FCNM	Rhesus Macaque	HEK293
	Ficolin-1 functions locally after inflammatory lesions in monocyte, macrophage, and granulocyte secretion, and is also present in serum, suggesting that it may play a role in systemic immunity. Ficolins recognize and bind to pathogens, leading to neutralization and conditioning, which subsequently activates the complement lectin pathway. Ficolin-1 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived Ficolin-1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P70740A

	FGL1 Protein, Human (HEK293, mFc, solution) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Human	HEK293
	FGL1 protein is the main ligand of LAG3 and can inhibit antigen-specific T cell activation, mediating the inhibitory function of LAG3 independently of MHC-II binding. FGL1 is secreted by liver cells and contributes to their growth. FGL1 Protein, Human (HEK293, mFc, solution) is the recombinant human-derived FGL1 protein, expressed by HEK293 , with C-mFc labeled tag.

HY-P72369

	FGL1 Protein, Human (Biotinylated, HEK293, Avi-His) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Human	HEK293
	FGL1 protein is the main ligand of LAG3 and can inhibit antigen-specific T cell activation, mediating the inhibitory function of LAG3 independently of MHC-II binding. FGL1 is secreted by liver cells and contributes to their growth. FGL1 Protein, Human (Biotinylated, HEK293, Avi-His) is the recombinant human-derived FGL1 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag.

HY-P704613

	FGL1 Protein, Human (249a.a, HEK293, Fc) fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1	Human	HEK293
	FGL1 protein is the main ligand of LAG3 and can inhibit antigen-specific T cell activation, mediating the inhibitory function of LAG3 independently of MHC-II binding. FGL1 is secreted by liver cells and contributes to their growth. FGL1 Protein, Human (249a.a, HEK293, Fc) is the recombinant human-derived FGL1 protein, expressed by HEK293, with N-hFc labeled tag.

HY-P702865

	FCN2 Protein, Human (P.pastoris, His) Ficolin-2; 37 kDa elastin-binding protein; Collagen/fibrinogen domain-containing protein 2; EBP-37; Ficolin-B; Ficolin-beta; FCNL	Human	P. pastoris
	FCN2 Protein, Human (P.pastoris, His) is the recombinant human-derived FCN2, expressed by P. pastoris , with N-6*His labeled tag.

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Source
Tag
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Free Sample	Yes No
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Cat. No.	Product Name	Chemical Structure

HY-176277S

Fibrinopeptide B, human-(Val-13C5,15N, Arg-13C6,15N4) TFA
Fibrinopeptide B, human-(Val- ¹³C₅, ¹⁵N, Arg- ¹³C₆, ¹⁵₄) TFA is the ¹³C- and ¹⁵N-labeled Fibrinopeptide B, human (HY-P1493). Fibrinopeptide B, human is a 14-aa peptide, released from the amino-terminus of β-chains of fibrinogen by thrombin .

Host:	Mouse (8) Rabbit (4)
Reactivity:	Human (11) Rat (1) Mouse (2)
Application:	IHC-P (6) ICC/IF (5) IP (1) WB (9) FC (9) ELISA (6)
Isotype:	IgG (3) IgG1 (4) IgG2a (2)
Conjugation:	Non-conjugated (12) Biotin (5)
Clonality:	Monoclonal (9) Recombinant (4)
Modification:	Unmodified (9)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83924

	Fibrinogen beta chain Antibody (YA3621) fibrinogen beta chain	WB, ELISA	Human
	Fibrinogen beta chain Antibody (YA3621) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Fibrinogen beta chain.

HY-P82151

	Fibrinogen gamma Chain Antibody (YA1896) FGG; fibrinogen gamma chain	WB, FC	Human
	Fibrinogen gamma Chain Antibody (YA1896) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fibrinogen gamma Chain.

HY-P85162

	Fibrinogen beta chain Antibody (YA4854) FGB; fibrinogen beta chain	WB, ELISA	Human
	Fibrinogen beta chain Antibody (YA4854) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Fibrinogen beta chain.

HY-P85163

	Fibrinogen gamma Chain Antibody (YA4855) FGG; fibrinogen gamma chain	WB, IHC-P, FC	Human
	Fibrinogen gamma Chain Antibody (YA4855) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Fibrinogen gamma Chain.

HY-P85164

	Fibrinogen gamma Chain Antibody (YA4856) FGG; fibrinogen gamma chain	WB, IHC-P, ICC/IF, FC, ELISA	Human
	Fibrinogen gamma Chain Antibody (YA4856) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Fibrinogen gamma Chain.

HY-P83924A

	Fibrinogen beta chain Antibody (YA3621)(PBS only) fibrinogen beta chain	WB, ELISA	Human
	Fibrinogen beta chain Antibody (YA3621) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Fibrinogen beta chain.

HY-P83925

	Fibrinogen gamma Chain Antibody (YA3622) FGG	IHC-P, ICC/IF, FC, ELISA	Human
	Fibrinogen gamma Chain Antibody (YA3622) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Fibrinogen gamma Chain.

HY-P83925A

	Fibrinogen gamma Chain Antibody (YA3622)(PBS only) FGG	IHC-P, ICC/IF, FC, ELISA	Human
	Fibrinogen gamma Chain Antibody (YA3622) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Fibrinogen gamma Chain.

HY-P82324

	Fibrinogen alpha Chain Antibody (YA2069) Fba5e; FGA; Fib; Fib2; Fibrinopeptide A	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	Fibrinogen alpha Chain Antibody (YA2069) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fibrinogen alpha Chain.

HY-P86724

	CD41 Antibody (YA6416) platelet glycoprotein IIb of IIb/IIIa complex; Integrin, alpha 2b(platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GPIIb; GTA; HPA3; CD 41; CD41 antigen; CD41a; CD41b; GP2b; GPalpha IIb; GPalphaIIb; Integrin alpha IIb; Integrin alpha IIb precursor; ITGA 2B; Integrin alpha 2b; ITGAB; Platelet fibrinogen receptor alpha; Platelet fibrinogen receptor alpha subunit; Platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; Platelet specific antigen bak; ITA2B_HUMAN.	WB, FC	Human
	CD41 Antibody (YA6416) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD41.

HY-P86724A

	CD41 Antibody (YA6416)(PBS only) platelet glycoprotein IIb of IIb/IIIa complex; Integrin, alpha 2b(platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GPIIb; GTA; HPA3; CD 41; CD41 antigen; CD41a; CD41b; GP2b; GPalpha IIb; GPalphaIIb; Integrin alpha IIb; Integrin alpha IIb precursor; ITGA 2B; Integrin alpha 2b; ITGAB; Platelet fibrinogen receptor alpha; Platelet fibrinogen receptor alpha subunit; Platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; Platelet specific antigen bak; ITA2B_HUMAN.	WB, FC	Human
	CD41 Antibody (YA6416) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD41.

HY-P86806

	CD41 Antibody (YA6499) antigen CD41 antibody; BDPLT16 antibody; BDPLT2 antibody; CD41 antibody; CD41B antibody; form 2 antibody; GP2B antibody; GPalpha IIb antibody; GPIIb antibody; GT antibody; antigen CD41 antibody; BDPLT16 antibody; BDPLT2 antibody; CD41 antibody; CD41B antibody; form 2 antibody; GP2B antibody; GPalpha IIb antibody; GPIIb antibody; GT antibody; GTA antibody; HPA3 antibody; Integrin alpha 2b antibody; Integrin alpha IIb antibody; Integrin alpha-IIb light chain antibody; Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) antibody; ITA2B_HUMAN antibody; Itga2b antibody; ITGAB antibody; platelet fibrinogen receptor, alpha subunit antibody; platelet glycoprotein IIb of IIb/IIIa complex antibody; Platelet membrane glycoprotein IIb antibody; platelet specific antigen BAK antibody; PPP1R93 antibody;	IHC-P, FC, ICC/IF	Mouse
	CD41 Antibody (YA6499) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD41.

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Host
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Free Sample	Yes No
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Cat. No.	Product Name		Classification

HY-150229

306-N16B		Cationic Lipids
306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .

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