Search Result

Results for "

fluorogenic substrate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (2) Aminopeptidase (1) Angiotensin Receptor (2) Angiotensin-converting Enzyme (ACE) (3) Apoptosis (1) Bacterial (1) Beta-secretase (1) Biochemical Assay Reagents (8) Caspase (16) Cathepsin (8) Ceramidase (1) Cholinesterase (ChE) (3) Cytochrome P450 (2) DNA Stain (1) Endogenous Metabolite (1) Enterovirus (1) Factor Xa (1) Fluorescent Dye (122) Furin (1) Glycosidase (1) HDAC (1) HIV (1) HIV Protease (1) MAGL (1) MMP (10) PAI-1 (2) Parasite (2) Phosphatase (3) Phospholipase (2) Proteasome (10) Reference Standards (3) SARS-CoV (1) Ser/Thr Protease (9) Sirtuin (2) Thrombin (3) Tyrosine Hydroxylase (1) Virus Protease (1)
By Research Areas:	Cancer (16) Cardiovascular Disease (7) Endocrinology (1) Infection (10) Inflammation/Immunology (9) Metabolic Disease (10) Neurological Disease (5)
Oligonucleotides:	Fluorescent Lipids (1)

193

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

134

Peptides

Natural
Products

Oligonucleotides

Targets Recommended: MARCKS

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-123633

4-Methylumbelliferyl β-D-Glucopyranoside	Glycosidase	Others
4-Methylumbelliferyl β-D-Glucopyranoside, a β-D-glucoside, is a fluorogenic substrate for β-glucosidase, utilizes to assay β-glucosidase activity . 4-Methylumbelliferyl β-D-Glucopyranoside releases the highly fluorescent 4-methylumbelliferyl (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively .

HY-101880

ADHP 2 Publications Verification 10-Acetyl-3,7-dihydroxyphenoxazine	Fluorescent Dye	Others
ADHP is a fluorogenic peroxidase substrate (λ_ex=530 nm, λ_em=590 nm).

HY-120166

DiFMUP 1 Publications Verification 6,8-Difluoro-4-methylumbelliferyl phosphate	Phosphatase	Others
DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader .

HY-D1670

Z-Gly-Pro-AMC 3 Publications Verification	Fluorescent Dye	Others
Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-Amino-4-methylcoumarin (HY-D0027). (λ_ex=380 nm, λ_em=465 nm) .

HY-D0994

4-Methylumbelliferyl phosphate 1 Publications Verification 4-MUP; MUP	Phosphatase	Others
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .

HY-136865

MeOSuc-AAPV-AMC	Fluorescent Dye	Others
MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (K_m: 362 μM, Ex=380 nm, Em=460 nm) .

HY-D0719

Fluorescein Diacetate 5+ Cited Publications 3,6-Diacetoxyfluoran; Di-O-acetylfluorescein	Fluorescent Dye	Others
Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-118135

4-Methylumbelliferyl-α-D-galactopyranoside 4MU-α-Gal	Fluorescent Dye	Others
4-Methylumbelliferyl-α-D-galactopyranoside (4MU-α-Gal), a substrate for α-galactosidase A (GLA), is a blue pro-fluorogenic substrate. 4-Methylumbelliferyl-α-D-galactopyranoside forms two products, galactose and fluorescent 4MU, upon cleavage by GLA .

HY-D1705

Ac-ANW-AMC	Proteasome	Inflammation/Immunology
Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm) .

HY-P1005

Ac-DEVD-AFC 10+ Cited Publications	Fluorescent Dye	Cancer
Ac-DEVD-AFC is a fluorogenic substrate (λ_ex=400 nm, λ_em=530 nm).

HY-D1080

EDANS 3 Publications Verification 1,5-EDANS	Fluorescent Dye	Others
EDANS (1,5-EDANS) is a novel and quenched **fluorogenic substrate** for assaying retroviral protease by resonance energy transfer (RET) .

HY-P2295

Dabcyl-KTSAVLQSGFRKME-Edans TFA 2 Publications Verification	SARS-CoV	Others
Dabcyl-KTSAVLQSGFRKME-Edans TFA is a fluorogenic peptide. Dabcyl-KTSAVLQSGFRKME-Edans TFA is used as the substrate to measure the enzymatic activities of protease forms. Dabcyl-KTSAVLQSGFRKME-Edans TFA has the potential for study 2019-nCoV (COVID-19) infection .

HY-137844

L-Leucine-7-amido-4-methylcoumarin hydrochloride Leu-AMC hydrochloride	Fluorescent Dye	Others
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro .

HY-P2179

MMP-1/MMP-9 Substrate, Fluorogenic	Fluorescent Dye MMP	Others
MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9 .Ex/Em = 340/440 nm

HY-145519

Mu-6S-Palm-β-Glc	Fluorescent Dye	Neurological Disease
Mu-6S-Palm-β-Glc is a fluorogenic substrate for palmitoyl-protein thioesterase (PPT). Mu-6S-Palm-β-Glc can be used for the research of neuronal ceroid lipofuscin disease in infants .

HY-134432B

Boc-Gln-Ala-Arg-AMC acetate 1 Publications Verification	Ser/Thr Protease	Others
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .

HY-123051

Ac-WLA-AMC	Proteasome	Inflammation/Immunology
Ac-WLA-AMC is a specific 20S constitutive proteasome β5 fluorogenic substrate .

HY-P4425

Gly-Phe-AMC	Biochemical Assay Reagents	Others
Gly-Phe-AMC is a fluorogenic peptide substrate consisting of a peptide sequence composed of glycine and phenylalanine, linked to the fluorophore AMC. Gly-Phe-AMC also serves as a cathepsin C substrate. Gly-Phe-AMC is widely used to detect the activity of various proteases .

HY-P3749

Mca-(ala7,lys(dnp)9)-bradykinin	Fluorescent Dye	Others
Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage .

HY-116862

Dibenzylfluorescein DBF	Cytochrome P450 Fluorescent Dye	Others
Dibenzylfluorescein (DBF) is a fluorogenic probe (Fluoresecent dye) that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein is typically used near its K_m value of 0.87-1.9 μM (Ex=485 nm，Em=535 nm). Dibenzylfluorescein is used to detect changes in CYP catalytic activity caused by drugs or disease .

HY-116583

Resorufin butyrate	Cholinesterase (ChE)	Metabolic Disease
Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm) .

HY-P5354A

FRETS-VWF73 TFA 1 Publications Verification	Fluorescent Dye	Others
FRETS-VWF73 TFA, a 73-amino-acid peptide, is a fluorogenic substrate for ADAMTS13 assay (Ex=340 nm; Em=450 nm) .

HY-123052

Ac-PAL-AMC	Proteasome	Inflammation/Immunology
Ac-PAL-AMC is a fluorogenic substrate specific for 20S proteasome LMP2/β1i activity .

HY-134435

Z-Arg-AMC hydrochloride 1 Publications Verification	Fluorescent Dye	Others
Z-Arg-AMC hydrochloride is a **fluorogenic substrate** for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .

HY-P1169

Ac-IETD-AFC 1 Publications Verification	Caspase	Others
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .

HY-113862

PHOME	Fluorescent Dye	Others
PHOME is a fluorogenic substrate for sEH. sEH can hydrolyze the epoxy ring in the PHOME substrate. PHOME can be used for fluorescent epoxide hydrolase assay .

HY-P2536

Mca-Ala-Pro-Lys(Dnp)-OH 2 Publications Verification	Angiotensin-converting Enzyme (ACE)	Others
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung .

HY-P4417

Ac-IEPD-AMC	Fluorescent Dye	Others
Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-P4419A

Boc-Asp(OBzl)-Pro-Arg-AMC acetate	Fluorescent Dye	Others
Boc-Asp(OBzl)-Pro-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Asp(OBzl)-Pro-Arg-AMC acetate undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-135036

4-Methylumbelliferyl butyrate	Fluorescent Dye	Others
4-Methylumbelliferyl butyrate (4-MUB) is a coumarin-based fluorogenic substrate used for the identification of M. catarrhalis C4- esterase. 4-Methylumbelliferyl butyrate can converse to the blue-emissive 4-methylumbelliferone (4-MU; HY-N0187) .

HY-W654272

4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium 4-MU-α-idoa 2-sulfate sodium	Fluorescent Dye	Metabolic Disease
4-Methylumbelliferyl-α-L-iduronide 2-sulfate (4-MU-α-idoa 2-sulfate) sodium is a fluorogenic substrate of iduronate-2-sulfatase (I2S). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be hydrolyzed by lysosomal enzyme α-l-iduronidase (IDUA) and release the fluorophore 4-Methylumbelliferone (HY-N0187). 4-Methylumbelliferyl-α-L-iduronide 2-sulfate sodium can be used to detect Hurler syndrome .

HY-134961

Z-Ala-Arg-Arg-AMC 1 Publications Verification fluorogenic Proteasome substrate; Z-ARR-AMC	Proteasome	Others
Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) is a fluorogenic substrate for assaying trypsin-like activity of proteasome .

HY-P1853

Abz-FR-K(Dnp)-P-OH	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Abz-FR-K(Dnp)-P-OH is an angiotensin I-converting enzyme (ACE) substrate and an internally quenched fluorogenic substrate for real time fluorescent assay .

HY-P2498A

Cathepsin D and E FRET Substrate acetate	Cathepsin	Cancer
Cathepsin D and E FRET Substrate acetate is a **fluorogenic substrate** for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D .

HY-P3484

Dnp-PLGLWA-DArg-NH2 TFA	MMP	Cancer
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm) .

HY-155667A

Z-Nle-Lys-Arg-AMC acetate	Cathepsin	Others
Z-Nle-Lys-Arg-AMC acetate is a fluorogenic peptide substrate that specifically monitors cathepsin B activity over a broad pH range .

HY-P2617A

Ac-WEHD-AFC TFA	Caspase	Inflammation/Immunology Cancer
Ac-WEHD-AFC TFA is a **fluorogenic caspase-1 substrate*. Ac-WEHD-AFC TFA can measure caspase-1 fluorogenic* activity and can be used for the research of tumor and inflammation .

HY-P4406

Abz-AGLA-Nba 1 Publications Verification	Fluorescent Dye	Others
Abz-AGLA-Nba is a fluorogenic substrate for the determination of protease activity. Abz-AGLA-Nba is hydrolyzed to release aminoacyl benzimide (Abz-AGLA) and 2-naphthylaminoacyl (Nba). The product Abz-AGLA produced by this hydrolysis reaction is fluorescent under ultraviolet light and can emit a fluorescent signal .

HY-D2284

SGPL1 fluorogenic substrate Sphingosine-1-phosphate lyase fluorogenic substrate	Fluorescent Dye	Cancer
SGPL1 fluorogenic substrate is the fluorogenic substrate of sphingosine-1-phosphate lyase (SGPL1) that can be used to measure the activity of SGPL1 .

HY-155002

*hCYP3A4 Fluorogenic* substrate 1**	Cytochrome P450	Metabolic Disease
hCYP3A4 Fluorogenic substrate 1 is a potrnt hCYP3A4 fluorogenic substrate with an K_m value of 0.36 μM. hCYP3A4 Fluorogenic substrate 1 can be used for cell and in vivo imaging .

HY-D1632

4-MU-α-GlcNS sodium	Fluorescent Dye	Others
4-MU-α-GlcNS sodium is a fluorogenic substrate of heparin sulphamidase, is desulfurized into 4-MU-α-GlcNH₂. 4-MU-α-GlcNH₂ can liberate 4-methylumbelliferone (4-MU, fluorescent product) via α-glucosaminidase catalysis, with the emission wavelength maxima of 445-454 nm. 4-MU-α-GlcNS sodium can be used to heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders researches .

HY-P4426A

Lys-Pro-AMC diTFA	Fluorescent Dye	Others
Lys-Pro-AMC diTFA is a fluorogenic substrate for the detection and measurement of the activity of specific enzymes .

HY-P4319

Boc-Glu-Lys-Lys-AMC	Fluorescent Dye	Others
Boc-Glu-Lys-Lys-AMC is a sensitive fluorogenic substrate for urokinase-activated plasmin .

HY-P2617

Ac-WEHD-AFC	Caspase	Inflammation/Immunology Cancer
Ac-WEHD-AFC is a **fluorogenic caspase-1 substrate*. Ac-WEHD-AFC can measure caspase-1 fluorogenic* activity and can be used for the research of tumor and inflammation .

HY-P5380

TNO211 Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2	MMP Fluorescent Dye	Others
TNO211 (Dabcyl-GABA-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH2) is a fluorogenic substrate, containing the MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencer combination. TNO211 can specifically detect MMP activity (Ex/Em = 340/485 nm) .

HY-P4323A

Boc-Gln-Arg-Arg-AMC acetate	Fluorescent Dye	Others
Boc-Gln-Arg-Arg-AMC acetate is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal .

HY-D1080R

EDANS (Standard) 1,5-EDANS (Standard)	Fluorescent Dye Reference Standards	Others
EDANS (1,5-EDANS) (Standard) is an analytical standard for EDANS. This product is intended for research and analytical applications. EDANS (1,5-EDANS) is a novel quenched fluorogenic substrate for the analysis of retroviral proteases by resonance energy transfer .

HY-P1448

Ac-Leu-Arg-AMC	Fluorescent Dye	Neurological Disease
Ac-Leu-Arg-AMC is a fluorogenic peptide substrate.

HY-P4312

Boc-Leu-Lys-Arg-AMC	Fluorescent Dye	Others
Boc-Leu-Lys-Arg-AMC is a fluorogenic substrate for the Kex2 endoprotease .

HY-P2498

Cathepsin D and E FRET Substrate	Cathepsin	Others
Cathepsin D and E FRET Substrate is a **fluorogenic substrate** for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D .

Cat. No.	Product Name	Type

HY-P1002

Suc-Leu-Leu-Val-Tyr-AMC Maximum Cited Publications 16 Publications Verification Suc-LLVY-AMC	Fluorescent Dye
Suc-Leu-Leu-Val-Tyr-AMC is a membrane-permeable calpain-specific fluorogenic substrate (Ex/Em = 390/480 nm) .

HY-101880

ADHP 2 Publications Verification 10-Acetyl-3,7-dihydroxyphenoxazine	Fluorescent Dye
ADHP is a fluorogenic peroxidase substrate (λ_ex=530 nm, λ_em=590 nm).

HY-D1670

Z-Gly-Pro-AMC 3 Publications Verification	Fluorescent Dye
Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-Amino-4-methylcoumarin (HY-D0027). (λ_ex=380 nm, λ_em=465 nm) .

HY-D0994

4-Methylumbelliferyl phosphate 1 Publications Verification 4-MUP; MUP	Fluorescent Dye
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .

HY-136865

MeOSuc-AAPV-AMC	Fluorescent Dye
MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (K_m: 362 μM, Ex=380 nm, Em=460 nm) .

HY-D0719

Fluorescein Diacetate 5+ Cited Publications 3,6-Diacetoxyfluoran; Di-O-acetylfluorescein	Fluorescent Dye
Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-101895

Fluorescein di(β-D-galactopyranoside) 5+ Cited Publications FDG	Fluorescent Dye
Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λ_ex=485 nm, λ_em=535 nm).

HY-P0019

Z-Gly-Gly-Arg-AMC 10+ Cited Publications	Fluorescent Dye
Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .

HY-15943

6-TAMRA 1 Publications Verification 6-Carboxytetramethylrhodamine	Fluorescent Dye
6-TAMRA (6-Carboxytetramethylrhodamine) is a fluorescent dye. 6-TAMRA is often used in combination with 6-FAM (HY-66021) as an acceptor or fluorescence quencher for fluorescence resonance energy transfer (FRET) in biochemical studies such as potassium ion detection and ribonuclease activity assays .

HY-D1705

Ac-ANW-AMC	Fluorescent Dye
Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm) .

HY-P1005

Ac-DEVD-AFC 10+ Cited Publications	Fluorescent Dye
Ac-DEVD-AFC is a fluorogenic substrate (λ_ex=400 nm, λ_em=530 nm).

HY-D1080

EDANS 3 Publications Verification 1,5-EDANS	Fluorescent Dye
EDANS (1,5-EDANS) is a novel and quenched **fluorogenic substrate** for assaying retroviral protease by resonance energy transfer (RET) .

HY-137844

L-Leucine-7-amido-4-methylcoumarin hydrochloride Leu-AMC hydrochloride	Fluorescent Dye
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro .

HY-P0019A

Z-Gly-Gly-Arg-AMC acetate 10+ Cited Publications	Fluorescent Dye
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm) .

HY-P1986

Z-DEVD-AFC	Fluorescent Dye
Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity .

HY-134432B

Boc-Gln-Ala-Arg-AMC acetate 1 Publications Verification	Fluorescent Dye
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .

HY-123051

Ac-WLA-AMC	Fluorescent Dye
Ac-WLA-AMC is a specific 20S constitutive proteasome β5 fluorogenic substrate .

HY-P3749

Mca-(ala7,lys(dnp)9)-bradykinin	Fluorescent Dye
Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage .

HY-116862

Dibenzylfluorescein

DBF

Fluorescent Dye

Dibenzylfluorescein (DBF) is a fluorogenic probe (Fluoresecent dye) that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein is typically used near its K_m value of 0.87-1.9 μM (Ex=485 nm，Em=535 nm). Dibenzylfluorescein is used to detect changes in CYP catalytic activity caused by drugs or disease .

HY-148073

MeO-Succ-Arg-Pro-Tyr-AMC TFA	Fluorescent Dye
MeO-Succ-Arg-Pro-Tyr-AMC TFA is a fluorogenic peptide substrate for chymotrypsin-like proteases that detects protease activity . (measured at 460 nm)

HY-116583

Resorufin butyrate	Fluorescent Dye
Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm) .

HY-134435

Z-Arg-AMC hydrochloride 1 Publications Verification	Fluorescent Dye
Z-Arg-AMC hydrochloride is a **fluorogenic substrate** for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .

HY-P1169

Ac-IETD-AFC 1 Publications Verification	Fluorescent Dye
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .

HY-113862

PHOME	Fluorescent Dye
PHOME is a fluorogenic substrate for sEH. sEH can hydrolyze the epoxy ring in the PHOME substrate. PHOME can be used for fluorescent epoxide hydrolase assay .

HY-P2536

Mca-Ala-Pro-Lys(Dnp)-OH 2 Publications Verification	Fluorescent Dye
Mca-Ala-Pro-Lys(Dnp)-OH, a specific ACE2 quenched fluorogenic substrate, can be used to detect ACE2 activity, such as urinary, heart and lung .

HY-D1634

Bz-FVR-AMC	Fluorescent Dye
Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a k_cat/K_m value of 1070 mM ^-1s ^-1. The high concentration of BZ-FVR-AMC inhibits the substrate .

HY-D1530

4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide	Fluorescent Dye
4-Methylumbelliferyl-N-acetyl-α-D-glucosaminide is a fluorogenic substrate for detecting α-N-acetylglucosaminidase .

HY-P3484

Dnp-PLGLWA-DArg-NH2 TFA	Fluorescent Dye
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm) .

HY-D2284

SGPL1 fluorogenic substrate Sphingosine-1-phosphate lyase fluorogenic substrate	Fluorescent Dye
SGPL1 fluorogenic substrate is the fluorogenic substrate of sphingosine-1-phosphate lyase (SGPL1) that can be used to measure the activity of SGPL1 .

HY-D1632

4-MU-α-GlcNS sodium

Fluorescent Dye

4-MU-α-GlcNS sodium is a fluorogenic substrate of heparin sulphamidase, is desulfurized into 4-MU-α-GlcNH₂. 4-MU-α-GlcNH₂ can liberate 4-methylumbelliferone (4-MU, fluorescent product) via α-glucosaminidase catalysis, with the emission wavelength maxima of 445-454 nm. 4-MU-α-GlcNS sodium can be used to heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders researches .

HY-P1448

Ac-Leu-Arg-AMC	Fluorescent Dye
Ac-Leu-Arg-AMC is a fluorogenic peptide substrate.

HY-D0719R

Fluorescein Diacetate (Standard) 3,6-Diacetoxyfluoran (Standard); Di-O-acetylfluorescein (Standard)	Fluorescent Dye
Fluorescein Diacetate (Standard) is the analytical standard of Fluorescein Diacetate. This product is intended for research and analytical applications. Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-129887

Fluorescein diphosphate tetraammonium	Fluorescent Dye
Fluorescein diphosphate tetraammonium is a fluorescent dye, it can be used as a fluorogenic substrate and generats fluorescein as a fluorescent product .

HY-D0146

Resorufin benzyl ether BzRes; 7-Benzyloxyresorufin; 7-Benzyloxyphenoxazone	Fluorescent Dye
Resorufin benzyl ether (BzRes), a fluorogenic enzyme substrate, can be used to detect CYP3A4 enzyme activity. Resorufin benzyl ether modified with a recognizing moiety boronate, can be used for ONOO ^- detection via a self-immolation mechanism. Ex/Em=530-570 nm/590 nm .

HY-P3120

Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2	Fluorescent Dye
Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14). Mca-Pro-Leu-Ala-Cys(Mob)-Trp-Ala-Arg-Dap(Dnp)-NH2, upon cleavage by MMP-14, releases 7-methoxycoumarin-4-acetyl (Mca) (Ex/Em = 328/420 nm).

HY-P2616

Mca-YVADAP-Lys(Dnp)-OH	Fluorescent Dye
Mca-YVADAP-Lys(Dnp)-OH is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2) .

HY-D1026

CUG 3-Carboxyumbelliferyl-β-D-galactopyranoside	Fluorescent Dye
CUG (3-Carboxyumbelliferyl-β-D-galactopyranoside) is a fluorogenic substrate (λ_ex=386, λ_em=445 nm, ε=32K).

HY-DY1060

Suc-Leu-Leu-Val-Tyr-AMC (solution)	Fluorescent Dye
Suc-Leu-Leu-Val-Tyr-AMC (solution) is a membrane-permeable calpain-specific fluorogenic substrate (Ex/Em = 390/480 nm) . Solvent and concentration: DMSO: 20 mM

HY-D1647

7-Hydroxycoumarinyl-γ-linolenate	Fluorescent Dye
7-Hydroxycoumarinyl-γ-linolenate is a cytosolic phospholipase A₂ (cPLA₂) fluorogenic substrate. 7-Hydroxycoumarinyl-γ-linolenate can be used to monitor the enzymatic activity of cPLA₂ .

HY-W354821

4-Methylumbelliferyl Decanoate 4-MUD	Fluorescent Dye
4-Methyl-2-oxo-2H-1-benzopyran-7-yl decanoate is a fluorogenic substrate used to follow the hydrolytic activity of carboxylesterases .

HY-P3110

Ac-DNLD-AMC	Fluorescent Dye
Ac-WLA-AMC is a fluorogenic substrate of caspase-3. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity .

HY-P3098

Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2	Fluorescent Dye
Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1), MMP-3, and MMP-26. Mca-P-Cha-G-Nva-HA-Dap(DNP)-NH2 can be used to quantify MMP-1, MMP-3 and MMP-26 activity .

HY-W357142

3-Acetylumbelliferyl β-D-Glucopyranoside	Fluorescent Dye
3-Acetylumbelliferyl β-D-Glucopyranoside is a fluorogenic substrate for β-glucosidase and can be used as a positive control substrates for β-D-glucosidase .

HY-137928

H-Ala-4MβNA hydrochloride	Fluorescent Dye
H-Ala-4MβNA hydrochloride is a specific fluorogenic substrate for aminopeptidase M .

HY-P3475

Mca-VDQMDGW-K(Dnp)-NH2	Fluorescent Dye
Mca-VDQMDGWK-(Dnp)-NH2 is a fluorogenic substrate for caspase-3 and can be used to quantify caspase-3 activity .

HY-P3362

Ac-IETD-AMC	Fluorescent Dye
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .

HY-D1740

Dihydrotetramethylrosamine DHTM Ros	Fluorescent Dye
Dihydrotetramethylrosamine (DHTM Ros) is a fluorogenic substrate for peroxidase that oxidizes to fluorescent tetramethylrosamine chloride.

HY-P2614

Mca-DEVDAP-K(Dnp)-OH	Fluorescent Dye
Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3 .

HY-D1532

DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS	Fluorescent Dye
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye, and can be applied in a fluorogenic substrate for an aspartyl proteinase from human malaria parasite .

HY-D0994A

4-Methylumbelliferyl phosphate disodium 4-MUP disodium; MUP disodium	Fluorescent Dye
4-Methylumbelliferyl phosphate (4-MUP) disodium, an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate disodium is also a nerve agent simulant .

Cat. No.	Product Name	Type

HY-D0719

Fluorescein Diacetate 5+ Cited Publications 3,6-Diacetoxyfluoran; Di-O-acetylfluorescein	Biochemical Assay Reagents
Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-D0719R

Fluorescein Diacetate (Standard) 3,6-Diacetoxyfluoran (Standard); Di-O-acetylfluorescein (Standard)	Biochemical Assay Reagents
Fluorescein Diacetate (Standard) is the analytical standard of Fluorescein Diacetate. This product is intended for research and analytical applications. Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-123000

4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside

Biochemical Assay Reagents

4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is a fluorogenic substrate for studying the enzymatic activity of α-galactosidase. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside is used to analyze enzyme activity in various biological samples, helping scientists gain insight into the function of the enzyme in vivo. 4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-galactopyranoside can also be used to screen potential compounds to inhibit or activate this enzyme.

HY-137164

Ala-Ala-Phe-AMC	Biochemical Assay Reagents
Ala-Ala-Phe-AMC serves as a fluorogenic substrate that exhibits positively charged properties, making it suitable for assessing proteolytic activity.

HY-W286423

L-Pyroglutamic acid 7-amido-4-methylcoumarin	Biochemical Assay Reagents
L-Pyroglutamic acid 7-amido-4-methylcoumarin is a fluorogenic substrate for pyroglutamate aminopeptidase 1 (PGP-1) .

HY-W283359

4-Methylumbelliferyl β-D-ribofuranoside	Biochemical Assay Reagents
4-Methylumbelliferyl β-D-ribofuranoside is a fluorogenic substrate of β-ribosidase .

HY-W776853

4-Methylumbelliferyl β-D-N,N',N'',N'''-tetraacetylchitotetraoside

Biochemical Assay Reagents

4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside is a fluorogenic substrate with activity for lysozyme assays. 4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside can be used to study enzyme activity and its applications in biomedicine. 4-Methylumbelliferyl β-DN,N',N'',N'''-tetraacetylchitotetraoside exhibits high sensitivity in analyzing enzyme reactions in biological samples.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N15826

RBM1-151	Lipid	Fluorescent Dye Ceramidase
RBM1-151, a 1-deoxy derivative and vinilog of RBM14-C12 (HY-150163), as a fluorogenic substrate of Amidases (HY-P2736) (E_x/E_m). RBM1-151 is hydrolyzed by acid ceramidase (AC) (( ^appK_m = 7.0 μM; ^appV_max = 99.3 nM/min), N-acylethanolamine-hydrolyzing acid amidase ( ^appK_m = 0.73 μM; ^appV_max = 0.24 nM/min), and fatty Acid amide hydrolase (FAAH) ( ^appK_m = 3.6 μM; ^appV_max = 7.6 nM/min) but not by other ceramidases. RBM1-151 is applicable for basic biological studies of lipid amidase function, as well as potential diagnostic/prognostic evaluations of diseases involving dysregulated AC, NAAA, or FAAH (Farber disease, cancer) .

Cat. No.	Product Name		Classification

HY-D2284

SGPL1 fluorogenic substrate Sphingosine-1-phosphate lyase fluorogenic substrate		Fluorescent Lipids
SGPL1 fluorogenic substrate is the fluorogenic substrate of sphingosine-1-phosphate lyase (SGPL1) that can be used to measure the activity of SGPL1 .

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