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halogenated

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48

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1

Fluorescent Dye

8

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6

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4

Isotope-Labeled Compounds

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17596
    Closantel
    Maximum Cited Publications
    11 Publications Verification

    		 Parasite Infection
    Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing .
    Closantel
  • HY-Y0678
    1,3,5-Trimethoxybenzene
    1 Publications Verification

    TRIMETHYL PHLOROGLUCINOL

    		 Biochemical Assay Reagents Others
    1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl +) and free bromine (Br +). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .
    1,3,5-Trimethoxybenzene
  • HY-17598
    Rafoxanide
    5+ Cited Publications

    		 Oxidative Phosphorylation Parasite p38 MAPK Raf Apoptosis Infection Cancer
    Rafoxanide is a poent, orally active halogenated salicylaniline agent with antiparasitic activity. Rafoxanide interferes with energy metabolism in trematodes by uncoupling oxidative phosphorylation. Rafoxanide is also found to be a potent inhibitor of the BRAF V600E mutant protein, which is important in colorectal cancer. Rafoxanide can be used for the control of infestation with Hemonchus species or Fasciola species in sheep and cattle as well as Oestrus ovis in sheep. Rafoxanide can also be used for cancer research .
    Rafoxanide
  • HY-17596A
    Closantel sodium
    Maximum Cited Publications
    11 Publications Verification

    		 Parasite Infection
    Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing .
    Closantel sodium
  • HY-124467
    Difludiazepam

    Ro 07-4065

    		 GABA Receptor Neurological Disease
    Difludiazepam (Ro 07-4065), a benzodiazepine derivative, is a GABAA receptor ligand with an IC50 of 4.1 nM. Difludiazepam binds to an allosteric site on the GABAA receptor to potentiate the receptor's response to GABA, reducing neuron excitability. Difludiazepam contains halogenated groups at the ortho position of its phenyl ring .
    Difludiazepam
  • HY-D0169A
    Phenol Red sodium salt
    1 Publications Verification

    Phenolsulfonephthalein sodium salt

    		 Fluorescent Dye Glutathione Peroxidase Others
    Phenol red (Phenolsulfonephthalein) sodium salt is a pH indicator dye. Phenol Red sodium salt is also an antagonist of rat P2X1R. Phenol Red sodium salt enhances the halogenating activity of myeloperoxidase. Phenol Red sodium salt shows a distinct color change from pink to yellow in a positive pH reaction .
    Phenol Red sodium salt
  • HY-106673
    Hydrocortisone buteprate
    1 Publications Verification

    Hydrocortisone probutate; HBP

    		 Glucocorticoid Receptor Inflammation/Immunology
    Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation .
    Hydrocortisone buteprate
  • HY-15537
    Tilbroquinol
    1 Publications Verification

    		 Parasite Bacterial Infection
    Tilbroquinol is an orally active halogenated hydroxyquinoline antiprotozoal agent, mainly used for anti-amoebic infections . Tilbroquinol targets intestinal protozoa and Entamoeba histolytica to eliminate parasites in the intestinal lumen. Tilbroquinol can be used in research related to intestinal infections, intestinal amoebiasis and hepatic amoebiasis .
    Tilbroquinol
  • HY-W011168
    8-Bromo-2'-deoxyguanosine

    		Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Inflammation/Immunology Cancer
    8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H2O2-Cl --Br - system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .
    8-Bromo-2'-deoxyguanosine
  • HY-41465
    4-Chlorobenzoic acid

    		Drug Intermediate Others
    4-Chlorobenzoic acid is a halogenated aromatic compound that can be used as an industrial chemical and an intermediate in drug synthesis. 4-Chlorobenzoic acid is a persistent organic micropollutant and can be biodegraded through a direct dehalogenation pathway .
    4-Chlorobenzoic acid
  • HY-N6694
    4-Bromo A23187

    		Calcium Channel Bacterial Apoptosis Antibiotic Infection Cancer
    4-Bromo A23187 is a halogenated analog of the highly selective calcium ionophore A-23187. 4-Bromo A23187, a calcium modulator, induces apoptosis in different cells, including HL-60 cells .
    4-Bromo A23187
  • HY-W003129
    2-Bromo-4-chloropyridine

    		Drug Intermediate Bacterial Infection
    2-Bromo-4-chloropyridine is a halogenated pyridine derivative that serves as a synthetic intermediate. 2-Bromo-4-chloropyridine undergoes Suzuki-Miyaura coupling with 4-tert-butylphenylboronic acid (HY-W007389). 2-Bromo-4-chloropyridine facilitates the construction of compounds with broad-spectrum antibacterial activity .
    2-Bromo-4-chloropyridine
  • HY-A0135
    Enflurane

    		Potassium Channel Neurological Disease
    Enflurane, a volatile anaesthetic, is a potent inhibitor of high conductance Ca 2+-activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by headspace gas chromatography-mass spectrometry .
    Enflurane
  • HY-W003601
    2-Bromo-4-fluoropyridine

    		Biochemical Assay Reagents Others
    2-Bromo-4-fluoropyridine is a synthetic halogenated heterocyclic organic compound and a key intermediate in the pharmaceutical and agrochemical industries. 2-Bromo-4-fluoropyridine can be used to synthesize bioactive molecules through cross-coupling reactions, such as Suzuki coupling or Buchwald-Hartwig amination.
    2-Bromo-4-fluoropyridine
  • HY-59299
    3-Bromothiophene

    		Biochemical Assay Reagents Drug Intermediate Others
    3-Bromothiophene is a bromine atom-substituted 3-halogenated thiophene. Polymers of 3-Bromothiophene are conductive polymers and have potential optoelectronic application value. Additionally, 3-Bromothiophene serves as a key intermediate for the synthesis of a variety of important pharmaceuticals, agrochemicals, and cosmetics .
    3-Bromothiophene
  • HY-125922
    (22R)-Budesonide

    (22R)-BUD

    		 Glucocorticoid Receptor Drug Isomer Inflammation/Immunology
    (22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity .
    (22R)-Budesonide
  • HY-W010062
    4-Chlorophenylacetic acid

    		Drug Derivative Cytochrome P450 Estrogen Receptor/ERR Metabolic Disease Cancer
    4-Chlorophenylacetic acid is a halogenated phenylacetic acid derivative. 4-Chlorophenylacetic acid is a potent aromatase inhibitor and antagonizes estrogen signaling. 4-Chlorophenylacetic acid can provide carbon and energy for Pseudomonas sp. strain CBS3. 4-Chlorophenylacetic acid is effective against estrogen-induced mammary tumorigenesis .
    4-Chlorophenylacetic acid
  • HY-W011972
    Bromocholine bromide

    		Biochemical Assay Reagents Others
    2-Bromo-N,N,N-trimethylethanaminium bromide is a quaternary ammonium salt consisting of a positively charged 2-bromo-N,N,N-trimethylethylamine cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It can also be used as a halogenating agent, for example in the bromination of olefins.
    Bromocholine bromide
  • HY-32746
    5-Bromo-2-fluoropyridine

    		Biochemical Assay Reagents Others
    5-Bromo-2-fluoropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 5-Bromo-2-fluoropyridine easily reacts with amines to synthesize halogenated pyridine and pyrimidine. 5-Bromo-2-fluoropyridine can be used as a model substrate to explore their efficiency and selectivity through successive SNAr substitution reactions and transition-metal-catalyzed cross-coupling reaction without an intervening purification step .
    5-Bromo-2-fluoropyridine
  • HY-I0834
    (S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran

    		Microtubule/Tubulin Cancer
    (S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran (compound 2d), a halogenated Phenstatin analog, is a microtubule destabilizing agent. (S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran shows anticancer activities .
    (S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran
  • HY-13742
    Ropidoxuridine

    IPdR

    		 HSV Cancer
    Ropidoxuridine (IPdR) is a novel orally available, halogenated thymidine analog and is a potential radiosensitizer for use in human tumors.
    Ropidoxuridine
  • HY-17596S
    Closantel-13C6

    		Isotope-Labeled Compounds Parasite Infection
    Closantel- 13C6 is the 13C6 labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
    Closantel-13C6
  • HY-Y0678R
    1,3,5-Trimethoxybenzene (Standard)

    		Reference Standards Biochemical Assay Reagents Others
    1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl+) and free bromine (Br+). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .
    1,3,5-Trimethoxybenzene (Standard)
  • HY-168350
    Chlorphine

    		Opioid Receptor Neurological Disease
    Chlorphine is a neuroactive halogenated opioid analog .
    Chlorphine
  • HY-W585826
    Antiblaze 100

    Antiblaze V6

    		 Biochemical Assay Reagents Others
    Antiblaze 100 (Antiblaze V6) is a halogenated organophosphate flame retardant .
    Antiblaze 100
  • HY-B0718
    Methoxyflurane

    DA-759

    		 Potassium Channel Neurological Disease
    Methoxyflurane disrupts neuronal transmission by interfering with the release and re-uptake of neurotransmitters at post-synaptic terminals, or altering ionic conductance following receptor activation . Methoxyflurane is an analgesic agent that provides rapid short-term analgesia. Methoxyflurane may shows a effective non-opioid treatment option for trauma pain .
    Methoxyflurane
  • HY-129756
    Thioacetanilide

    N-Phenylthioacetamide

    		 Biochemical Assay Reagents Metabolic Disease
    Thioacetanilide (N-Phenylthioacetamide) is a sulfur-containing thioamide derivative of acetanilide. Thioacetanilide displays a solvent‑dependent Z/E isomeric distribution, preferring the E conformation in polar hydrogen‑bonding solvents and the Z conformation in halogenated solvents. Thioacetanilide serves as a substrate for metabolic desulfurization and aromatic hydroxylation. Thioacetanilide is mainly metabolized via desulfurization and 4‑hydroxylation of the aromatic ring in Rattus norvegicus, and the released sulfur integrates into the total body sulfur pool. Thioacetanilide is well absorbed in rats, and more than 90% of the dose is excreted in urine as conjugated metabolites after oral administration .
    Thioacetanilide
  • HY-133647
    Dibromoacetaldehyde

    		Others Others
    Dibromoacetaldehyde, a halogenated product, is a byproduct in drinking water and has genotoxicity .
    Dibromoacetaldehyde
  • HY-17596AR
    Closantel sodium (Standard)

    		Reference Standards Parasite Infection
    Closantel (sodium) (Standard) is the analytical standard of Closantel (sodium). This product is intended for research and analytical applications. Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing .
    Closantel sodium (Standard)
  • HY-17596R
    Closantel (Standard)

    		Reference Standards Parasite Infection
    Closantel (Standard) is the analytical standard of Closantel. This product is intended for research and analytical applications. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing .
    Closantel (Standard)
  • HY-136824
    Napyradiomycin A1

    		Bacterial Antibiotic Infection Cancer
    Napyradiomycin A1 is one enantioselective compound of napyradiomycins. napyradiomycins are an intriguing family of halogenated natural products with activity against several tumor cell lines as well as some bacterial strains .
    Napyradiomycin A1
  • HY-133629
    1,1,1,3-Tetrachloroacetone

    		Drug Intermediate Others
    1,1,1,3-Tetrachloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .
    1,1,1,3-Tetrachloroacetone
  • HY-133625
    1,1-Dibromo-3-chloroacetone

    		Biochemical Assay Reagents Others
    1,1-Dibromo-3-chloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .
    1,1-Dibromo-3-chloroacetone
  • HY-131556
    4-Iodoamphetamine hydrochloride

    p-Iodoamphetamine hydrochloride

    		 5-HT Receptor Neurological Disease
    4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated amphetamine featuring an iodine atom at the para position of the phenyl group. 4-Iodoamphetamine hydrochloride selectively induces serotonin release and inhibits reuptake by rat brain synaptosomes.
    4-Iodoamphetamine hydrochloride
  • HY-133628
    1,1,3-Tribromo-3-chloroacetone

    		Biochemical Assay Reagents Others
    1,1,3-Tribromo-3-chloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .
    1,1,3-Tribromo-3-chloroacetone
  • HY-133626
    1,1-Dibromo-3,3-dichloroacetone

    		Drug Derivative Others
    1,1-Dibromo-3,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .
    1,1-Dibromo-3,3-dichloroacetone
  • HY-133627
    1,3-Dibromo-1,3-dichloroacetone

    		Drug Derivative Others
    1,3-Dibromo-1,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .
    1,3-Dibromo-1,3-dichloroacetone
  • HY-106673R
    Hydrocortisone buteprate (Standard)

    Hydrocortisone probutate (Standard); HBP (Standard)

    		 Glucocorticoid Receptor Reference Standards Inflammation/Immunology
    Hydrocortisone buteprate (Standard) is the analytical standard of Hydrocortisone buteprate. This product is intended for research and analytical applications. Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation .
    Hydrocortisone buteprate (Standard)
  • HY-41465R
    4-Chlorobenzoic acid (Standard)

    		Reference Standards Drug Intermediate Others
    4-Chlorobenzoic acid (Standard) is the analytical standard of 4-Chlorobenzoic acid (HY-41465). This product is intended for research and analytical applications. 4-Chlorobenzoic acid is a halogenated aromatic compound that can be used as an industrial chemical and an intermediate in drug synthesis. 4-Chlorobenzoic acid is a persistent organic micropollutant and can be biodegraded through a direct dehalogenation pathway .
    4-Chlorobenzoic acid (Standard)
  • HY-125922S
    (22R)-Budesonide-d6

    Dexbudesonide-d6; (22R)-BUD-d6

    		 Isotope-Labeled Compounds Glucocorticoid Receptor Drug Isomer Inflammation/Immunology
    (22R)-Budesonide-d6 (Dexbudesonide-d6) is deuterium labeled (22R)-Budesonide. (22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity .
    (22R)-Budesonide-d6
  • HY-W010062R
    4-Chlorophenylacetic acid (Standard)

    		Reference Standards Cytochrome P450 Estrogen Receptor/ERR Drug Derivative Metabolic Disease Cancer
    4-Chlorophenylacetic acid (Standard) is the analytical standard of 4-Chlorophenylacetic acid. This product is intended for research and analytical applications. 4-Chlorophenylacetic acid is a halogenated phenylacetic acid derivative. 4-Chlorophenylacetic acid is a potent aromatase inhibitor and antagonizes estrogen signaling. 4-Chlorophenylacetic acid can provide carbon and energy for Pseudomonas sp. strain CBS3. 4-Chlorophenylacetic acid is effective against estrogen-induced mammary tumorigenesis .
    4-Chlorophenylacetic acid (Standard)
  • HY-17598R
    Rafoxanide (Standard)

    		Oxidative Phosphorylation Reference Standards Parasite p38 MAPK Raf Apoptosis Infection Cancer
    Rafoxanide (Standard) is the analytical standard of Rafoxanide. This product is intended for research and analytical applications. Rafoxanide is a poent, orally active halogenated salicylaniline agent with antiparasitic activity. Rafoxanide interferes with energy metabolism in trematodes by uncoupling oxidative phosphorylation. Rafoxanide is also found to be a potent inhibitor of the BRAF V600E mutant protein, which is important in colorectal cancer. Rafoxanide can be used for the control of infestation with Hemonchus species or Fasciola species in sheep and cattle as well as Oestrus ovis in sheep. Rafoxanide can also be used for cancer research .
    Rafoxanide (Standard)
  • HY-W767399
    8-Bromo-2'-deoxyguanosine-13C,15N2

    		Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Cancer
    8-Bromo-2'-deoxyguanosine- 13C, 15N2 is the 13C- and 15N-labeled 8-Bromo-2'-deoxyguanosine (HY-W011168). 8-Bromo-2'-deoxyguanosine is an inflammation-related DNA halogenated adduct and an early biomarker of inflammation-induced oxidative tissue damage. The formation of 8-Bromo-2'-deoxyguanosine precedes that of oxidative and nitrative products, and it can be generated via the MPO-H2O2-Cl --Br - system. 8-Bromo-2'-deoxyguanosine serves as the immunogen for preparing the monoclonal antibody mAb8B3, which can be used to detect early DNA modifications in preclinical models; its urinary level also increases significantly in inflammatory disease models. 8-Bromo-2'-deoxyguanosine can also be produced in the dermis of UV-B irradiated mice, and the extract of Coprinus comatus significantly reduces its level. 8-Bromo-2'-deoxyguanosine finds applications in studies related to inflammatory diseases, diabetes, hepatocellular carcinoma, and UV-B induced skin inflammation .
    8-Bromo-2'-deoxyguanosine-13C,15N2
  • HY-171818
    6-Bromo-3-indolyl α-D-glucopyranoside

    		Biochemical Assay Reagents Others
    6-Bromo-3-indolyl α-D-glucopyranoside is a halogenated 3-indolyl-α-D-glucopyranoside derivative .
    6-Bromo-3-indolyl α-D-glucopyranoside
  • HY-N16856
    (11R)-12-Chloronootkaton-11-ol

    		Drug Derivative Others
    (11R)-12-Chloronootkaton-11-ol is a natural sesquiterpene.
    (11R)-12-Chloronootkaton-11-ol
  • HY-166480S
    (22R)-Budesonide-d8

    (22R)-BUD-d8

    		 Isotope-Labeled Compounds Glucocorticoid Receptor Drug Isomer Inflammation/Immunology
    (22R)-Budesonide-d8 ((22R)-BUD-d8) is the deuterium labeled (22R)-Budesonide. (22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity .
    (22R)-Budesonide-d8
  • HY-B1644
    Fenticlor

    		Bacterial Inflammation/Immunology
    Fenticlor is a topical antibacterial agent that can be used for treating acne. Fenticlor can cause photosensitivity reactions and is a known cause of phototoxic dermatitis .
    Fenticlor
  • HY-W679111
    1,3-Dichloro-5-ethyl-5-methylhydantoin

    		Biochemical Assay Reagents Others
    1,3-Dichloro-5-ethyl-5-methylhydantoin serves as the active ingredient in toilet tablets .
    1,3-Dichloro-5-ethyl-5-methylhydantoin

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