348 Results for "

medicine

" in MedChemExpress (MCE) Product Catalog:
Products (348)

348 Results for "medicine" in MCE Product Catalog:

80
Berberine sulfate
Berberine sulfate
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80 Cited Publications
Cat. No.: HY-N0716B
CAS No.: 633-66-9
Synonyms: Natural Yellow 18 sulfate
Category:  

Alkaloids Ranunculaceae Coptis chinensis Franch. Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology

Target:  

Antibiotic Topoisomerase Autophagy Bacterial Reactive Oxygen Species (ROS) Parasite Apoptosis PI3K Akt Caspase JNK AP-1 NF-κB

Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability .
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74
Shikonin
Shikonin
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74 Cited Publications
Cat. No.: HY-N0822
CAS No.: 517-89-5
Synonyms: C.I. 75535; Isoarnebin 4
Category:  

Quinones Plants Lithospermum erythrorhizon Sieb. et Zucc. Disease Research Fields Boraginaceae Naphthalene Quinones Cancer

Target:  

Exosomes Chloride Channel Pyruvate Kinase NF-κB TNF Receptor HIV AIM2

Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC50 of 6.5 μM . Shikonin is a specific pyruvate kinase M2 (PKM2) inhibitor and can also inhibit TNF-α and NF-κB pathway . Shikonin decreases exosome secretion through the inhibition of glycolysis . Shikonin inhibits AIM2 inflammasome activation .
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54
Berberine hemisulfate
Berberine hemisulfate
0 Images
54 Cited Publications
Cat. No.: HY-N0716A
CAS No.: 316-41-6
Synonyms: Natural Yellow 18 hemisulfate
Category:  

Infection Alkaloids Ranunculaceae Coptis chinensis Franch. Metabolic Disease Plants Disease Research Fields Isoquinoline Alkaloids Cancer

Target:  

Antibiotic Topoisomerase Autophagy Bacterial Reactive Oxygen Species (ROS) Apoptosis PI3K Akt Caspase JNK AP-1 NF-κB

Berberine hemisulfate is the hemisulfate form of Berberine (HY-N0716). Berberine hemisulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian. Berberine hemisulfate exhibits anti-inflammatory, antibiobic, antitumor, cardiovascular protective and neuroprotective activity .
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31
EDTA disodium
EDTA disodium
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31 Cited Publications
Cat. No.: HY-W018746
CAS No.: 139-33-3
Synonyms: Ethylenediaminetetraacetic acid disodium
EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
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25
Lycorine hydrochloride
Lycorine hydrochloride
0 Images
25 Cited Publications
Cat. No.: HY-N0289
CAS No.: 2188-68-3
Category:  

Alkaloids Lycoris radiata (L’Her.) Herb. Pyrrole Alkaloids Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology Amaryllidaceae Cancer

Target:  

Autophagy Bacterial Virus Protease

Lycorine hydrochloride is the main active ingredient of the herbal medicine derived from Lycoris radiata (L’Her.) Herb. and is also a melanoma vasculogenic inhibitor and has anti-tumor activity . Lycorine hydrochloride effectively inhibits mitotic proliferation of Hey1B cells (IC50 of 1.2 μM) .
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19
Gastrodin
Gastrodin
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19 Cited Publications
Cat. No.: HY-N0115
CAS No.: 62499-27-8
Synonyms: Gastrodine
Category:  

Natural Products Neurological Disease Gastrodia elata Bl. Anti-aging Orchidaceae Phenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis Ferroptosis

Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H2O2-induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia .
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11
Physcion
Physcion
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11 Cited Publications
Cat. No.: HY-N0108
CAS No.: 521-61-9
Synonyms: Parietin; Rheochrysidin
Category:  

Polygonaceae Marine natural products Plants Biological Pesticide Research Agricultural Research Infection Quinones Microorganisms Anthraquinones Rheum officinale Baill. Phenols Polyphenols Disease Research Fields Inflammation/Immunology Marine microorganism Cancer

Target:  

Bacterial Toll-like Receptor (TLR) NF-κB Apoptosis Autophagy Antibiotic

Physcion (Parietin), an anthraquinone derivative derived from the traditional Chinese medicine rhubarb, is an effective oral active 6-phosphogluconate dehydrogenase inhibitor with blood-brain barrier permeability, with IC50 and Kd values of 38.5 μM and 26.0 μM, respectively. Additionally, Physcion is an inhibitor of the <>bTLR4/NF-κB signaling pathway, exhibiting anti-inflammatory, antibacterial, and anticancer effects, and can induce Apoptosis and Autophagy in cancer cells .
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9
Echinatin
Echinatin
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9 Cited Publications
Cat. No.: HY-N0269
CAS No.: 34221-41-5
Category:  

Flavonoids Chalcones Leguminosae Phenols Polyphenols Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Target:  

Apoptosis Autophagy NOD-like Receptor (NLR)

Echinatin is a chalcone isolated from the Chinese herbal medicine Gancao with hepatoprotective and anti-inflammatory effects . Echinatin can be quickly absorbed and eliminated and extensively distributed with an absolute bioavailability of approximately 6.81% in Rat .
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8
Homoplantaginin
Homoplantaginin
0 Images
8 Cited Publications
Cat. No.: HY-N1949
CAS No.: 17680-84-1
Category:  

Flavonoids Flavones Labiatae Cassia Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

Free Radical Scavengers TNF Receptor NF-κB

Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia with antiinflammatory and antioxidant properties. Homoplantaginin could inhibit TNF-α and IL-6 mRNA expression, IKKβ and NF-κB phosphorylation.
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8
Schaftoside
Schaftoside
0 Images
8 Cited Publications
Cat. No.: HY-N0703
CAS No.: 51938-32-0
Category:  

Flavonoids Eleusine indica (Linn.) Gaertn. Leguminosae Flavones Gramineae Plants Disease Research Fields Glycyrrhiza uralensis Fisch. Inflammation/Immunology

Target:  

Toll-like Receptor (TLR) MyD88 Dynamin Mitochondrial Metabolism Autophagy

Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission .
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7
Vanillin
Vanillin
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7 Cited Publications
Cat. No.: HY-N0098
CAS No.: 121-33-5
Synonyms: p-Vanillin; m-Methoxy-p-hydroxybenzaldehyde; p-Hydroxy-m-methoxybenzaldehyde
Category:  

Monophenols Other Diseases Phenols Endogenous metabolite Disease Research Fields

Target:  

Environmental Pollutants Endogenous Metabolite

Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine.
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7
Oroxin B
Oroxin B
0 Images
7 Cited Publications
Cat. No.: HY-N1435
CAS No.: 114482-86-9
Category:  

Flavonoids Flavones Phenols Polyphenols Plants Bignoniaceae Oroxylum indicum (Linn.) Bentham ex Kurz Disease Research Fields Cancer

Target:  

Apoptosis PI3K PTEN Autophagy

Oroxin B (OB) is a BBB-permeable flavonoid isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent. Oroxin B (OB) possesses obvious inhibitory effect and induces early apoptosis rather than late apoptosis on liver cancer cells through upregulation of PTEN, down regulation of COX-2, VEGF, PI3K, and p-AKT. Oroxin B (OB) selectively induces tumor-suppressive ER stress in malignant lymphoma cells .
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5
Nicotiflorin
Nicotiflorin
0 Images
5 Cited Publications
Cat. No.: HY-N1475
CAS No.: 17650-84-9
Category:  

Flavonols Flavonoids Carthamus tinctorius L. Phenols Polyphenols Plants Compositae

Target:  

Others

Nicotiflorin is a flavonoid glycoside extracted from a traditional Chinese medicine Carthamus tinctorius. Nicotiflorin shows potent antiglycation activity and neuroprotection effects.
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5
Mogroside V
Mogroside V
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5 Cited Publications
Cat. No.: HY-N0502
CAS No.: 88901-36-4
Category:  

Triterpenes Terpenoids Cucurbitaceae Metabolic Disease Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields Sweeteners Food Research

Target:  

Reactive Oxygen Species (ROS)

Mogroside V is a the major active constituent of a traditional Chinese medicine Siraitiae Fructus. Mogroside V reduces the intracellular reactive oxygen species (ROS) levels and enhances mitochondrial function. Mogroside V has anti-oxidative, anti-diabetic and anti-carcinogenic effects. Mogroside V can be used for diabetic diseases research .
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4
Jujuboside A
Jujuboside A
0 Images
4 Cited Publications
Cat. No.: HY-N0659
CAS No.: 55466-04-1
Category:  

Triterpenes Terpenoids Plants Actaea dahurica Turcz. ex Fisch. & C. A. Mey. Rhamnaceae

Target:  

GABA Receptor

Jujuboside A is a glycoside extracted from Semen Ziziphi Spinosae, a Chinese herbal medicine used to treat insomnia and anxiety.
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4
Danthron
Danthron
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4 Cited Publications
Cat. No.: HY-B0923
CAS No.: 117-10-2
Synonyms: Dantron; Chrysazin; 1,8-Dihydroxyanthraquinone
Category:  

Quinones Labiatae Anthraquinones Samanea saman (Jacq.) Merr. Phenols Polyphenols Plants Disease Research Fields Cancer

Target:  

AMPK Autophagy Bacterial Virus Protease

Danthron is a natural product extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.
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4
Anemarrhenasaponin I
Anemarrhenasaponin I
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4 Cited Publications
Cat. No.: HY-N4213
CAS No.: 163047-21-0
Category:  

Cardiovascular Disease Liliaceae Anemarrhena asphodeloides Bunge Plants Disease Research Fields Steroids

Target:  

Others

Anemarrhenasaponin I, a traditional Chinese medicine, shows remarkable inhibiting effect on platelet aggregation.
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4
Gamabufotalin
Gamabufotalin
0 Images
4 Cited Publications
Cat. No.: HY-N0883
CAS No.: 465-11-2
Synonyms: Gamabufagin
Category:  

Animals Disease Research Fields Cancer Steroids

Target:  

VEGFR

Gamabufotalin (Gamabufagin), a main active compound isolated from Chinese medicine Chansu, has been shown to strongly inhibit cancer cell growth and inflammatory response. Gamabufotalin could inhibite angiogenesis by inhibiting the activation of VEGFR-2 signaling pathways.
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4
Muscone
Muscone
0 Images
4 Cited Publications
Cat. No.: HY-N0633
CAS No.: 541-91-3
Category:  

Cardiovascular Disease Animals Ketones, Aldehydes, Acids Disease Research Fields

Target:  

Environmental Pollutants TNF Receptor P-glycoprotein NF-κB NOD-like Receptor (NLR) Interleukin Related

Muscone is the main active monomer of traditional Chinese medicine musk. Muscone inhibits NF-κB and NLRP3 inflammasome activation. Muscone remarkably decreases the levels of inflammatory cytokines (IL-1β, TNF-α and IL-6), and ultimately improves cardiac function and survival rate .
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3
L-Threonine
L-Threonine
0 Images
3 Cited Publications
Cat. No.: HY-N0658
CAS No.: 72-19-5
Category:  

Human Gut Microbiota Metabolites Microorganisms Anti-aging Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed .
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