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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
635 Results for "
metaphase chromosome spreads
" in MedChemExpress (MCE) Product Catalog:
Products (635)
635 Results for "metaphase chromosome spreads" in MCE Product Catalog:
67
67 Publications Verification
Synonyms: R428; BGB324
Target:
Research Areas:
Bemcentinib (R428) is a selective and orally active Axl inhibitor with an IC50 of 14 nM. Bemcentinib retards cancer cell migration and invasion. Bemcentinib exhibits >100-fold selectivity for Axl versus Abl and 50- and >100-fold selectivity over TAM family kinases Mer and Tyro3, respectively, in cells. Bemcentinib blocks tumor spread and prolongs survival in models of metastatic breast cancer .
22
22 Cited Publications
Target:
Research Areas:
SF1670 is a potent and specific phosphatase and tensin homolog deleted on chromosome 10 (PTEN) inhibitor .
17
17 Cited Publications
Synonyms: DMP 266; EFV; L-743726
Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture .
14
14 Cited Publications
Cat. No.: HY-P7218
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL33; DVS27-Related Protein; Prev. C9orf26; chromosome 9 Open Reading Frame 26 (NF-HEV); NF-HEV; Interleukin-1 Family, Member 11; IL1F11; Alternative Protein IL33; Interleukin-33; IL-1F11; DVS27; NFEHEV; Nuclear Factor From High Endothelial Venules; IL-33
Species:
Mouse
Source:
E. coli
9
9 Cited Publications
Synonyms: 1,10-Phenanthroline monohydrate
9
8
7
7 Cited Publications
Cat. No.: HY-P1416
CAS No.: 881188-51-8
7
Target:
Research Areas:
BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys 496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
7
7 Cited Publications
Cat. No.: HY-P1416A
5
5 Cited Publications
Cat. No.: HY-P74743
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MRAP; Fat Cell-Specific Low Molecular Weight Protein; Prev. C21orf61; Fat Tissue-Specific Low MW Protein; FALP; chromosome 21 Open Reading Frame 61; B27; GCCD2; MRAP1; Melanocortin 2 Receptor Accessory Protein; Melanocortin-2 Receptor Accessory Protein
Species:
Human
Source:
HEK293
4
Target:
4
4 Cited Publications
Target:
Research Areas:
NSC 617145 is a selective werner syndrome helicase (WRN) helicase inhibitor with an IC50 value of 230 nM. NSC 617145 inhibits WRN ATPase, and induces double-strand breaks (DSB) and chromosomal abnormalities. NSC 617145 shows selective for WRN over BLM, FANCJ, ChlR1, RecQ, and UvrD helicases .
4
4 Cited Publications
Cat. No.: HY-B0281A
CAS No.: 66357-59-3
Target:
Research Areas:
Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine hydrochloride antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine hydrochloride inhibits breast tumor development and spread in mice .
4
4 Cited Publications
Cat. No.: HY-B0693
CAS No.: 66357-35-5
Target:
Research Areas:
Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine inhibits breast tumor development and spread in mice .
4
4 Cited Publications
Cat. No.: HY-P7041
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL33; DVS27-Related Protein; Prev. C9orf26; chromosome 9 Open Reading Frame 26 (NF-HEV); NF-HEV; Interleukin-1 Family, Member 11; IL1F11; Alternative Protein IL33; Interleukin-33; IL-1F11; DVS27; NFEHEV; Nuclear Factor From High Endothelial Venules; IL-33
Species:
Human
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P7846
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BRD4; Mitotic chromosome-Associated Protein; Bromodomain Containing 4; Bromodomain-Containing Protein 4; HUNKI; chromosome-Associated Protein; HUNK1; Bromodomain-Containing Protein 4 Variant; MCAP; Bromodomain-Containing 4; CAP; Protein HUNK1; FSHRG4; BRD4 Protein; Female Sterile Homeotic Related Gene 4; CDLS6
Species:
Human
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P70154
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EPCAM; HEA125; Prev. TACSTD1; CO-17A; Prev. MIC18; EGP314; Prev. M4S1; EGP34; Tumor-Associated Calcium Signal Transducer 1; CD326; TROP1; MOC31; KSA; 17-1A; GA733-2; Ly74; Ber-Ep4; MH99; Ep-CAM; Membrane Component, chromosome 4, Surface Marker (35kD Glyco
Species:
Human
Source:
HEK293
3
3
3 Cited Publications
Cat. No.: HY-P72337
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CGAS; D4; Prev. C6orf150; DANGER Family Member 4; Prev. MB21D1; CGAMP Synthase; H-CGAS; chromosome 6 Open Reading Frame 150; Mab-21 Domain-Containing Protein 1; Protein MB21D1; 2'3'-CGAMP Synthase; Cyclic GMP-AMP Synthase; Mab-21 Domain Containing 1
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
