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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
64 Results for "
modified nucleoside
" in MedChemExpress (MCE) Product Catalog:
Products (64)
64 Results for "modified nucleoside" in MCE Product Catalog:
4
Category:
Natural Products Other disease Disease markers Endogenous metabolite Disease Research Fields Cancer
Target:
2
2 Cited Publications
2
2 Cited Publications
Cat. No.: HY-122524A
CAS No.: 81100-62-1
Research Areas:
7-Methylguanosine iodide is an iodide of 7-Methylguanosine (HY-122524). 7-Methylguanosine is a modified nucleoside widely present in various RNAs and a key metabolite of the 5'-cap structure of eukaryotic mRNA. 7-Methylguanosine plays important roles in stabilizing RNA structures, regulating translation, and other aspects .
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1
1 Cited Publications
Cat. No.: HY-W019670
CAS No.: 3768-18-1
1
Research Areas:
N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA .
1
1 Cited Publications
Cat. No.: HY-W039442
CAS No.: 64183-27-3
Target:
2′-Deoxy-2′-fluoroadenosine is a fluorinated deoxyadenosine with antitumor and antiviral activity, able to interfere with viral or cancer cell replication by being incorporated into DNA. 2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP .
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1 Cited Publications
Synonyms: N2-methylguanine
1
Research Areas:
5-Iodo-cytidine (5-Iodo-D-cytidine) is a purine nucleoside analog that acts as an intermediate in organic synthesis. 5-Iodo-cytidine serves as a chemically modified nucleotide to replace partial cytidine residues in in vitro transcription, enhancing the translation efficiency and stability of chemically modified mRNA. Purine nucleoside analogs exhibit broad anti-tumor activity and target indolent lymphoid malignancies. 5-Iodo-cytidine can be used in mRNA therapy and tumor-related research .
1
1 Cited Publications
Target:
Research Areas:
5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides .
1
1 Cited Publications
Cat. No.: HY-W011824R
CAS No.: 2140-76-3
Research Areas:
2′-O-Methyluridine (Standard) is the analytical standard of 2′-O-Methyluridine (HY-W001824). This product is intended for research and analytical applications. 2’-O-Methyluridine is a modified nucleoside that can be found in T. thermophile tRNA. 2’-O-Methyluridine level in serum is decreased in patients with breast cancer.
Cat. No.: HY-W011824
CAS No.: 2140-76-3
Target:
Research Areas:
2’-O-Methyluridine is a modified nucleoside that can be found in T. thermophile tRNA. 2’-O-Methyluridine level in serum is decreased in patients with breast cancer .
Cat. No.: HY-W013260
CAS No.: 2140-71-8
2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase. 2'-O-Methylguanosine results in apoptotic changes of cells .
Cat. No.: HY-45492
CAS No.: 144089-97-4
Synonyms: 2'-F-ibu-dG Phosphoramidite
Research Areas:
DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be employed for oligonucleotide synthesis. DMT-2'Fluoro-DG(IB) Amidite can be used to prepare 4'-modified 2'-deoxy-2'-fluorouridine .
Cat. No.: HY-174497
eGFP mRNA expresses green fluorescent protein derived from the jellyfish Aequorea victoria. eGFP is a commonly used direct-detection reporter gene in mammalian cell culture, which produces bright green fluorescence. This product is synthesized without modified nucleosides, with a Cap1 version cap analog at the 5' end and a 100nt PolyA tail at the 3' end. It can be used as a positive reference for IVT (in vitro transcription) or LNP delivery systems.
Cat. No.: HY-18398
CAS No.: 24719-82-2
Synonyms: N6-(N-Threonylcarbonyl)adenosine
Target:
Research Areas:
N6-Threonylcarbamoyladenosine (N6-(N-Threonylcarbonyl) adenosine) is a ubiquitous nucleoside that modifies tRNA .
Cat. No.: HY-23789
CAS No.: 473278-54-5
Synonyms: 2'-O-MOE-rG
Cat. No.: HY-W570885
CAS No.: 251647-54-8
Target:
Research Areas:
2'-O-MOE-rC is a 2'-O-MOE modified nucleoside. 2'-O-MOE-rC can be used for synthesis of DNA .
Cat. No.: HY-W010744
CAS No.: 93778-57-5
Synonyms: 5'-O-DMT-dI; 2'-Deoxy-5'-O-DMT-inosine
Research Areas:
DMT-dI (5'-O-DMT-dI) is a deoxyribonucleoside containing a hypoxanthine base. DMT-dI can be used to prepare convertible nucleoside derivatives to prepare modified oligonucleotides complementary to target genes for gene editing. DMT-dI can be used to study various conditions, disorders or diseases modified by adenosine .
Cat. No.: HY-152296
CAS No.: 56973-12-7
Research Areas:
8-Methyladenosine is a modified adenosine nucleoside. Through methylation at the 8-position, 8-Methyladenosine confers bacterial resistance to five classes of antibiotics that bind to the ribosomal peptidyl transferase center. 8-Methyladenosine can be used in studies of antibiotic-resistant bacterial infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
