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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
131 Results for "
nuclear factor (NF)-
" in MedChemExpress (MCE) Product Catalog:
Products (131)
131 Results for "nuclear factor (NF)-" in MCE Product Catalog:
37
37 Publications Verification
Target:
SC75741 is a broad and efficient NF-κB inhibitor with an IC50 of 200 nM for p65 . SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-κB subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins .
14
14 Cited Publications
Cat. No.: HY-P7218
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL33; DVS27-Related Protein; Prev. C9orf26; Chromosome 9 Open Reading Frame 26 (NF-HEV); NF-HEV; Interleukin-1 Family, Member 11; IL1F11; Alternative Protein IL33; Interleukin-33; IL-1F11; DVS27; NFEHEV; nuclear factor From High Endothelial Venules; IL-33
Species:
Mouse
Source:
E. coli
9
9 Cited Publications
Synonyms: Isoquercetin; Quercetin 3-glucoside
Category:
Apocynaceae Flavonols Flavonoids Phenols Polyphenols Plants Apocynum venetum Linn. Disease Research Fields Cancer
Target:
6
6 Cited Publications
Synonyms: 4-Caffeoylquinic acid; 4-O-Caffeoylquinic acid
5
4
4 Cited Publications
Cat. No.: HY-P81238
Synonyms: Phospho-NF-KB p65 (Ser536) ;
NF-kB p65 (phospho S536); p-NF-κB p65(Phospho-Ser536); RELA(phospho S536); NF kB P65; NF-kB p65; NFKBp65; NF-κBp65; p65 NF kappaB; p65 NFkB; NFKBp65; RELA; Transcription factor p65; v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65)); V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian); v-rel reticuloendotheliosis viral oncogene homolog A; p65NFKB; Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NFKB 3; NFKB3; nuclear factor NF Kappa B p65 Subunit; nuclear factor of kappa light polypeptide gene enhancer in B cells 3; nuclear factor Of Kappa Light Polypeptide Gene Enhancer In B Cells; TF65_HUMAN. NFκB-p65; NFκB p65; NF κB-p65; NFκBp65;
4
4 Cited Publications
Cat. No.: HY-P7041
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL33; DVS27-Related Protein; Prev. C9orf26; Chromosome 9 Open Reading Frame 26 (NF-HEV); NF-HEV; Interleukin-1 Family, Member 11; IL1F11; Alternative Protein IL33; Interleukin-33; IL-1F11; DVS27; NFEHEV; nuclear factor From High Endothelial Venules; IL-33
Species:
Human
Source:
E. coli
3
Target:
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P9958A
CAS No.: 615258-40-7
Target:
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P1832A
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P73681
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: RELA; NF-Kappa-B Transcription factor P65; Prev. NFKB3; P65 Iso5 Isoform Delta 10; nuclear factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 3; Alternative Protein RELA; P65; NF-Kappa-B P65delta3; V-Rel Avian Reticuloendotheliosis Viral Oncogene
Species:
Human
Source:
E. coli
3
Category:
Infection Colophony Pinaceae Ketones, Aldehydes, Acids Metabolic Disease Plants Disease Research Fields Inflammation/Immunology
Target:
2
2 Cited Publications
Cat. No.: HY-N0632
CAS No.: 65497-07-6
2
Category:
Alkaloids Other Alkaloids Ranunculaceae Aconitum carmichaeli Debx. Plants Disease Research Fields Cancer
Target:
2
2
2
2 Cited Publications
Synonyms: Isoquercetin (Standard); Quercetin 3-glucoside (Standard)
Target:
1
Research Areas:
Flumethasone (Flumetasone) is an orally active, high selective and potent glucocorticoid receptor (GR) agonist. Flumethasone activates GR to inhibit nuclear factor kappa B (NF-κB)-mediated pro-inflammatory cytokine production (TNF-α, IL-1β) and promotes anti-inflammatory gene expression (IL-10), while also regulating metabolic enzyme activity (tyrosine aminotransferase induction). Flumethasone is promising for research of inflammatory diseases, cancer, and endocrine regulation .
1
1 Cited Publications
Cat. No.: HY-169703
CAS No.: 1251839-15-2
Target:
Research Areas:
SPA0355 is a thiourea derivative that has antioxidant and anti-inflammatory properties. SPA0355 inhibits the RANKL (receptor activator of nuclear factor κB ligand) induced osteoclast formation in primary bone marrow-derived macrophages. SPA0355 also suppresses the activation of the MAPKs, Akt, and NF-κB pathways. Additionally, SPA0355 promotes osteoblast differentiation, increases alkaline phosphatase activity, and enhances mineral nodule formation. SPA0355 can protect ovariectomized mice from bone loss by stimulating osteoblast differentiation and inhibiting osteoclast resorption, making it useful for studying postmenopausal osteoporosis .
1
1 Cited Publications
Cat. No.: HY-P70475
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL33; DVS27-Related Protein; Prev. C9orf26; Chromosome 9 Open Reading Frame 26 (NF-HEV); NF-HEV; Interleukin-1 Family, Member 11; IL1F11; Alternative Protein IL33; Interleukin-33; IL-1F11; DVS27; NFEHEV; nuclear factor From High Endothelial Venules; IL-33
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
