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Results for "

p97

" in MedChemExpress (MCE) Product Catalog:

By Targets:	p97 (28) Apoptosis (3) ATP Synthase (2) Autophagy (2) Bcr-Abl (1) Beclin1 (1) Caspase (2) CDK (1) CMV (1) Cyclin G-associated Kinase (GAK) (1) IRAK (1) JAK (1) Ligands for Target Protein for PROTAC (1) MAP4K (1) p62 (1) PROTACs (1) Reactive Oxygen Species (ROS) (1) Small Interfering RNA (siRNA) (7) Src (1)
By Research Areas:	Cancer (29) Infection (1) Inflammation/Immunology (2) Neurological Disease (1)
Click Chemistry:	PROTAC Synthesis (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (5) siRNAs (7)

Inhibitors & Agonists

Screening Libraries

Recombinant Proteins

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: p97

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-110078

Eeyarestatin I 10+ Cited Publications	p97 Apoptosis	Cancer
Eeyarestatin I, a potent endoplasmic reticulum-associated protein degradation (ERAD) inhibitor, is a potent protein translocation inhibitor. Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination. Eeyarestatin I interferes at a step prior to proteasomal degradation. Eeyarestatin I induces cell death via the proapoptotic protein NOXA and has anticancer effects .

HY-12861

CB-5083 Maximum Cited Publications 47 Publications Verification	p97	Cancer
CB-5083 is a first-in-class, potent, selective, and orally bioavailable inhibitor of the p97 AAA ATPase/VCP. CB-5083 selectively inhibits p97 through its D2 site with the IC₅₀ of 11 nM .

HY-15713

NMS-873 15+ Cited Publications	p97	Cancer
NMS-873 is a potent, selective allosteric *VCP/p97* inhibitor with an IC₅₀ value of 30 nM.

HY-15945

DBeQ 5+ Cited Publications JRF 12	p97 Autophagy Apoptosis	Cancer
DBeQ is a selective, potent, reversible, and ATP-competitive *p97* inhibitor, with an IC₅₀ value of 1.5 μM and 1.6 μM for p97(wt) and p97(C522A), respectively; DBeQ also inhibits Vps4 with an IC₅₀ of 11.5 μM.

HY-19795

ML240 5 Publications Verification	p97	Cancer
ML240 is a potent *p97* inhibitor, inhibiting p97 ATPase with IC₅₀ value of 100 nM.

HY-123872

MSC1094308 1 Publications Verification	p97	Cancer
MSC1094308 is a non-competitive and reversible VPS4B/p97 (VCP) (I/II type AAA ATPase) allosteric inhibitor, with IC₅₀ values of 0.71 μM and 7.2 μM for VPS4B and *p97, respectively . MSC1094308 inhibits the D2 ATPase activity by binding to a agentable hotspot of p97*. MSC1094308 can be used in study of cancer .

HY-128724

CB-5339 2 Publications Verification	p97	Cancer
CB-5339 is an oral activity potent *p97* inhibitor with an IC₅₀ <30 nM. CB-5339 can be used for leukemia research . CB-5339 extracted from WO2015109285A1 compound FF07.

HY-123636

UPCDC-30245	p97	Cancer
UPCDC-30245 is an allosteric p97 inhibitor with an IC₅₀ of approximately 27 nM . UPCDC-30245 inhibits the p97 mutant N660K similar to wild type (WT; IC₅₀=300 nM) and shows 3-fold resistance for p97 mutant T688A . UPCDC-30245 can be used in the research of cancer .

HY-19797A

ML241 hydrochloride	p97	Cancer
ML241 hydrochloride is a potent *p97* inhibitor, inhibiting p97 ATPase with IC₅₀ value of 100 nM.

HY-137342

SB1-G-187	PROTACs Src IRAK Bcr-Abl MAP4K Cyclin G-associated Kinase (GAK) CDK	Cancer
SB1-G-187 is a multi-target kinase PROTAC degrader with activity against various kinases including GCK, YES1, IRAK1 and LYN. SB1-G-187 induces degradation of target kinases via a *p97*-dependent pathway, and forms ternary complexes with CRBN and specific functional kinases. SB1-G-187 can be used in tumor-related research. (Pink: multi-target kinase ligand (HY-125142); Blue: CRBN ligand (HY-A0003); Black: linker) .

HY-11067

WHI-P97 1 Publications Verification	JAK	Inflammation/Immunology
WHI-P97 is a potent and selective JAK-3 inhibitor. WHI-P97 is effective in preventing the development allergic asthma in vivo .

HY-138233

KUS121	p97	Neurological Disease Inflammation/Immunology
KUS121, a valosin-containing protein (VCP, p97) modulator with significant neuroprotective effects, attenuates ischemic retinal cell death via suppressing endoplasmic reticulum stress .

HY-15714

NMS-859 1 Publications Verification	p97	Cancer
NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC₅₀s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.

HY-W111581

Copper(II) diethyldithiocarbamate 1 Publications Verification Diethyldithiocarbamic acid copper salt	Apoptosis Caspase	Cancer
Copper(II) diethyldithiocarbamate (Diethyldithiocarbamic acid copper salt) is a Copper(II) and diethyldithiocarbamate coordination polymer. Copper(II) diethyldithiocarbamate binds tightly to NPL4 and induces its aggregation, disrupting the p97-NPL4-UFD1 pathway. Copper(II) diethyldithiocarbamate causes ubiquitinated proteins accumulation and impairs waste proteins degradation, thus resulting in cell apoptosis. Copper(II) diethyldithiocarbamate inhibits tumor growth in MDA-MB-231 xenograft mice models. Copper(II) diethyldithiocarbamate can be used for the research of cancer, such as breast cancer .

HY-139606

*VCP/p97* inhibitor-1**	p97	Cancer
VCP/p97 inhibitor-1 is a potent inhibitor of *VCP/p97* (also called Cdc48, CDC-. 48, or Ter94) with an IC₅₀ of 54.7 nM. VCP/p97 inhibitor-1 causes the dysregulation of protein homeostasis and disturbs the degradation of misfolded polypeptides by the ubiquitin-proteasome system (UPS) .

HY-19797

ML241	p97	Cancer
ML241 is a potent, selective and competitive p97 ATPase inhibitor with an IC₅₀ of 0.11 μM. ML241 can be used for the research of cancer .

HY-148122

NW 1028	p97	Cancer
NW 1028 is a potent *VCP/p97* inhibitor. NW 1028 targets the ND1L domain of p97 and inhibits the degradation of a p97-dependent reporter. NW 1028 has good binding affinity with K_d values of 100 and 285 nM for ND1L and full length p97, respectively. NW 1028 has the function of regulating the mitotic spindle of cells .

HY-124776

NPD8733	p97	Cancer
NPD8733 is an inhibitor of cancer cell-enhanced fibroblast migration. NPD8733 specifically binds to valosin-containing protein (VCP)/p97, a member of the ATPase-associated with diverse cellular activities (AAA+) protein family. NPD8733 has the potential for the research of cancer diseases .

HY-174984

*VCP/p97* IN-3**	p97 Caspase p62	Cancer
VCP/p97 IN-3 is a *VCP/p97* allosteric inhibitor. VCP/p97 IN-3 shows the inhibitory activity against the VCP proteins with an IC₅₀ of 9 nM and the mutant VCP proteins with IC₅₀ of 12 nM (N660K) and 19 nM (V474A/D649A). VCP/p97 IN-3 increases K48-linked ubiquitination and the level of cleaved caspase-3. VCP/p97 IN-3 activates ER-stress and the UPR. VCP/p97 IN-3 inhibits tumor growth in RPMI-8226 cell subcutaneous xenograft mouse models. VCP/p97 IN-3 can be used for the study of multiple myeloma .

HY-RS15621

VCP Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
VCP Human Pre-designed siRNA Set A contains three designed siRNAs for VCP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

VCP Human Pre-designed siRNA Set A VCP Human Pre-designed siRNA Set A

HY-179257

p97-IN-2	p97	Cancer
p97-IN-2 (Compound 14) is a p97 ATPase (IC₅₀ = 0.6 μM) inhibitor. p97-IN-2 can inhibit cell proliferation, such as HCT15 (IC₅₀ = 1.1 μM) and SW403 (IC₅₀ = 0.8 μM) cells. p97-IN-2 can be used for cancer research .

HY-174844

p97-IN-1	p97	Cancer
p97-IN-1 is an orally active *p97* inhibitor (IC₅₀ = 26 nM). p97-IN-1 can significantly inhibit the proliferation of tumor cells. p97-IN-1 can be used for research on acute myeloid leukemia (AML) .

HY-174847

*VCP/p97* IN-2**	p97	Cancer
VCP/p97 IN-2 (Compound V13) is a *VCP/p97* inhibitor with IC₅₀ of 32 nM for p97. VCP/p97 IN-2 has excellent antitumor activities and significantly inhibits tumor growth in Molm-13 xenograft mice model. VCP/p97 IN-2 can be used for acute myeloid leukemia (AML) research .

HY-168005

NSC799462	p97 ATP Synthase	Cancer
NSC799462 is a triazole inhibitor of p97 ATPase. NSC799462 inhibits p97 ATPase activity (IC₅₀ = 15 nM) by binding to a specific site on *p97* and causing local changes in the *p97* structure .

HY-19795R

ML240 (Standard)	p97	Cancer
ML240 (Standard) is the analytical standard of ML240. This product is intended for research and analytical applications. ML240 is a potent p97 inhibitor, inhibiting p97 ATPase with IC50 value of 100 nM.

HY-155026

UPCDC30766	p97	Cancer
UPCDC30766 is a potent allosteric inhibitor of *p97* (IC₅₀ of 12 nM; EC₅₀ of 0.23 μM in cells). UPCDC30766 can be used for the research of colon cancer .

HY-168006

NSC819701	p97 ATP Synthase	Cancer
NSC819701 is a triazole inhibitor of the p97 ATPase. NSC819701 inhibits the activity of p97 ATPase by binding to a specific site of *p97* .

HY-118460

ACJI-99C VCP/p97-IN-PPA	p97	Cancer
ACJI-99C (VCP/p97-IN-PPA) is a selective covalent *p97/VCP* ATPase inhibitor with an IC₅₀ value of 0.6 μM. ACJI-99C binds with p97 active site residues to block ATPase activity. ACJI-99C irreversibly blocks degradation of p97-dependent protein in cells. ACJI-99C inhibits proliferation of cancer cells, including p97 inhibitor-resistant lines. ACJI-99C can be used for the research of colorectal cancer .

HY-124253

SMDC818909	p97	Cancer
SMDC818909 is an indole amide-derived uncompetitive inhibitor targeting p97 AAA+ ATPase, with an IC₅₀ of 3.5 μM and a K_a of 9.1 μM. SMDC818909 binds to the D2 ATPase domain of p97, preferentially associates with the ADP-bound conformation of p97, allosterically blocks the ATP hydrolysis cycle of p97, and inhibits its mediated intracellular protein homeostasis regulatory function. SMDC818909 is applied to the research and development of p97-targeted antitumor drugs, as well as studies on cancer-related proteotoxic stress mechanisms .

HY-125472

LC-1028	p97	Cancer
LC-1028 (Compound 20) is an irreversible, non-competitive, covalent *p97* inhibitor with a Ki ^app value of 33.2 nM. LC-1028 covalently modifies the cysteine residues (Cys105, Cys522, Cys535) of p97. LC-1028 can be used in the research of pancreatic cancer .

HY-183920

LC-1310	CMV p97	Infection
LC-1310 is an antiviral agent that targets and inhibits *p97, and it suppresses the in vitro replication of human cytomegalovirus (HCMV) with an EC₅₀* value of 0.3 μM. LC-1310 targets the D2 ATP-binding site of p97, downregulates the expression of early viral proteins, thereby blocking the transcription and proliferation of early viral genes. LC-1310 can be used for research on human cytomegalovirus infection .

HY-RS22177

Gab2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Gab2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gab2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Gab2 Mouse Pre-designed siRNA Set A Gab2 Mouse Pre-designed siRNA Set A

HY-RS11323

PSMD2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PSMD2 Human Pre-designed siRNA Set A contains three designed siRNAs for PSMD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PSMD2 Human Pre-designed siRNA Set A PSMD2 Human Pre-designed siRNA Set A

HY-RS04282

EIF4G2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
EIF4G2 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4G2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

EIF4G2 Human Pre-designed siRNA Set A EIF4G2 Human Pre-designed siRNA Set A

HY-RS15622

Vcp Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Vcp Mouse Pre-designed siRNA Set A contains three designed siRNAs for Vcp gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Vcp Mouse Pre-designed siRNA Set A Vcp Mouse Pre-designed siRNA Set A

HY-RS05368

GEMIN4 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
GEMIN4 Human Pre-designed siRNA Set A contains three designed siRNAs for GEMIN4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

GEMIN4 Human Pre-designed siRNA Set A GEMIN4 Human Pre-designed siRNA Set A

HY-RS02560

CFDP1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CFDP1 Human Pre-designed siRNA Set A contains three designed siRNAs for CFDP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CFDP1 Human Pre-designed siRNA Set A CFDP1 Human Pre-designed siRNA Set A

HY-183257

ATI-1	Autophagy Beclin1 Reactive Oxygen Species (ROS) p97	Cancer
ATI-1 is an autophagy initiation inhibitor. ATI-1 targets valosin-containing protein (VCP/p97, disrupts its interaction with UFL1, impairs UFMylation homeostasis associated with VCP, promotes polyubiquitination and degradation of Beclin1, and blocks the formation of early autophagosomes. ATI-1 induces synergistic death of autophagy-dependent malignant tumor cells under nutrient deprivation conditions, accompanied by decreased mitochondrial membrane potential, reduced ROS levels and lysosomal stress. ATI-1 exhibits anti-tumor efficacy in a pancreatic adenocarcinoma xenograft mouse model. ATI-1 can be used for the research of pancreatic adenocarcinoma and lung cancer .

HY-125142

AP-24567	Ligands for Target Protein for PROTAC	Cancer
AP-24567 is a Ligands for Target Protein for PROTAC, which can be used for the synthesis of SB1-G-187 (HY-137342) .

Cat. No.	Product Name

HY-L050

Ubiquitination Compound Library	482 compounds
Protein ubiquitination is an enzymatic post-translational modification in which an ubiquitin protein is attached to a substrate protein. Ubiquitination involves three main steps: activation, conjugation, and ligation, performed by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s), respectively. Ubiquitination affects cellular processes such as apoptosis, cell cycle, DNA damage repair, and membrane transportation, etc. by regulating the degradation of proteins (via the proteasome and lysosome), altering the cellular localization of proteins, affecting proteins activity, and promoting or preventing protein-protein interactions. Deregulation of ubiquitin pathway leads to many diseases such as neurodegeneration, cancer, infection and immunity, etc. MCE offers a unique collection of 482 small molecule modulators with biological activity used for ubiquitination research. Compounds in this library target the key enzymes in ubiquitin pathway. MCE Ubiquitination Compound Library is a useful tool for the research of ubiquitination regulation and the corresponding diseases.

Ubiquitination Compound Library

482 compounds

Protein ubiquitination is an enzymatic post-translational modification in which an ubiquitin protein is attached to a substrate protein. Ubiquitination involves three main steps: activation, conjugation, and ligation, performed by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s), respectively. Ubiquitination affects cellular processes such as apoptosis, cell cycle, DNA damage repair, and membrane transportation, etc. by regulating the degradation of proteins (via the proteasome and lysosome), altering the cellular localization of proteins, affecting proteins activity, and promoting or preventing protein-protein interactions. Deregulation of ubiquitin pathway leads to many diseases such as neurodegeneration, cancer, infection and immunity, etc.

MCE offers a unique collection of 482 small molecule modulators with biological activity used for ubiquitination research. Compounds in this library target the key enzymes in ubiquitin pathway. MCE Ubiquitination Compound Library is a useful tool for the research of ubiquitination regulation and the corresponding diseases.

Species:	Human (6) Mouse (2)
Tag:	His (4) Tag Free (2) GST (1) Fc (1)
Source:	HEK293 (2) Sf9 insect cells (3) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P705508

	VCP Protein, Human (sf9, GST) Transitional Endoplasmic Reticulum ATPase; TER ATPase; 15S Mg(2+)-ATPase p97 Subunit; Valosin-Containing Protein; VCP	Human	Sf9 insect cells
	VCP proteins are indispensable for Golgi stack dynamics, coordinating fragmentation during mitosis and postmitotic reorganization. It actively promotes the formation of the transitional endoplasmic reticulum (tER), enables ATP-dependent vesicle budding, and enables membrane transfer to the Golgi apparatus. VCP Protein, Human (sf9, GST) is the recombinant human-derived VCP protein, expressed by Sf9 insect cells , with N-GST labeled tag.

HY-P701679

	ERK3 Protein, Human (Inactive, L290V) MAPK6; Mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK	Human	E. coli
	ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human (L290V) is the recombinant human-derived ERK3 protein, expressed by E. coli , with tag free.

HY-P701680

	ERK3 Protein, Human (Inactive, L290V, His) MAPK6; Mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK	Human	E. coli
	ERK3 Protein, an atypical MAPK, phosphorylates MAP2 and MAPKAPK5. Interacting with MAPKAPK5, ERK3/MAPK6 undergoes Ser-189 phosphorylation, facilitating MAPKAPK5 activation. Activated MAPKAPK5 reciprocally phosphorylates ERK3/MAPK6. The complex's precise functional implications, especially in cell cycle entry, remain elusive. ERK3 Protein, Human (L290V, His) is the recombinant human-derived ERK3 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P70837

	KPNB1 Protein, Human (His) Importin subunit beta-1; Importin-90; Karyopherin subunit beta-1; Nuclear factor p97; Pore targeting complex 97 kDa subunit; PTAC97; KPNB1; NTF97	Human	E. coli
	KPNB1 is a key player in nuclear protein import, cooperating with adapter proteins such as importin-alpha to recognize nuclear localization signals (NLS) in cargo substrates. In autonomous mode, it acts as its own NLS receptor, facilitating docking of the import/substrate complex to the nuclear pore complex (NPC) via KPNB1. KPNB1 Protein, Human (His) is the recombinant human-derived KPNB1 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P701436

	VCPIP1 Protein, Human (sf9) VCPIP1; Deubiquitinating protein VCPIP1; Valosin-containing protein p97/p47 complex-interacting protein 1; Valosin-containing protein p97/p47 complex-interacting protein p135; VCP/p47 complex-interacting 135-kDa protein	Human	Sf9 insect cells
	The VCPIP1 protein is a multifunctional deubiquitinating enzyme that plays a crucial role in a variety of cellular processes. It is an integral component of DNA repair and postmitotic Golgi and endoplasmic reticulum reassembly, promoting VCP-mediated Golgi stacking and tER formation. VCPIP1 Protein, Human (sf9) is the recombinant human-derived VCPIP1 protein, expressed by sf9 insect cells , with tag free.

HY-P701435

	VCPIP1 Protein, Human (sf9, His) VCPIP1; Deubiquitinating protein VCPIP1; Valosin-containing protein p97/p47 complex-interacting protein 1; Valosin-containing protein p97/p47 complex-interacting protein p135; VCP/p47 complex-interacting 135-kDa protein	Human	Sf9 insect cells
	The VCPIP1 protein is a multifunctional deubiquitinating enzyme that plays a crucial role in a variety of cellular processes. It is an integral component of DNA repair and postmitotic Golgi and endoplasmic reticulum reassembly, promoting VCP-mediated Golgi stacking and tER formation. VCPIP1 Protein, Human (sf9, His) is the recombinant human-derived VCPIP1 protein, expressed by sf9 insect cells , with C-8*His labeled tag.

HY-P76496

	Melanotransferrin/CD228 Protein, Mouse (HEK293, His) Melanotransferrin; MTf; CD228; MELTF; MFI2	Mouse	HEK293
	Melanotransferrin/CD228 protein is involved in cellular iron uptake, undergoing internalization and recycling to the cell membrane. Each subunit binds a single iron atom, suggesting a role in intracellular iron transport. Melanotransferrin/CD228 also exhibits potential zinc binding, showcasing versatile metal ion interactions. Melanotransferrin/CD228 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Melanotransferrin/CD228 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76495

	Melanotransferrin/CD228 Protein, Mouse (HEK293, Fc) Melanotransferrin; MTf; CD228; MELTF; MFI2	Mouse	HEK293
	Melanotransferrin/CD228 protein is involved in cellular iron uptake, undergoing internalization and recycling to the cell membrane. Each subunit binds a single iron atom, suggesting a role in intracellular iron transport. Melanotransferrin/CD228 also exhibits potential zinc binding, showcasing versatile metal ion interactions. Melanotransferrin/CD228 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Melanotransferrin/CD228 protein, expressed by HEK293 , with C-hFc labeled tag.

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Cat. No.
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Source
Tag
Accession
Gene ID
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Host:	Mouse (5) Rabbit (4)
Reactivity:	Human (9) Rat (6) Mouse (8) Monkey (2) Dog (2)
Application:	IHC-P (6) ICC/IF (6) IF-Tissue (1) IP (3) IHC-F (2) WB (8) FC (3) ELISA (3)
Isotype:	IgG (4) IgG1 (2) IgG2a (2)
Conjugation:	Non-conjugated (9)
Clonality:	Monoclonal (6) Recombinant (3)
Modification:	Unmodified (6)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84401

	VCP Antibody (YA4098) p97; TERA; CDC48; FTDALS6	WB, ICC/IF, FC, ELISA	Human, Mouse
	VCP Antibody (YA4098) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to VCP.

HY-P84401A

	VCP Antibody (YA4098)(PBS only) p97; TERA; CDC48; FTDALS6	WB, ICC/IF, FC, ELISA	Human, Mouse
	VCP Antibody (YA4098) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to VCP.

HY-P82630

	VCP Antibody (YA2375) 15S Mg(2+) ATPase p97 subunit; ALS14; ATPase p97; CDC48; IBMPFD; p97; TER ATPase; TERA; VCP; Yeast Cdc48p homolog	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	VCP Antibody (YA2375) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VCP.

HY-P82630A

	VCP Antibody (YA2375)(PBS only) 15S Mg(2+) ATPase p97 subunit; ALS14; ATPase p97; CDC48; IBMPFD; p97; TER ATPase; TERA; VCP; Yeast Cdc48p homolog	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	VCP Antibody (YA2375) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to VCP.

HY-P88132

	PSMD2 (Proteasome 26S S2) Antibody (YA7816) p97; RPN1; S2; TRAP2	WB, IHC-P, ICC/IF	Human, Dog, Rat, Monkey, Mouse
	PSMD2 (Proteasome 26S S2) Antibody (YA7816) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PSMD2 (Proteasome 26S S2).

HY-P88132A

	PSMD2 (Proteasome 26S S2) Antibody (YA7816)(PBS only) p97; RPN1; S2; TRAP2	IHC-P, ICC/IF	Human, Dog, Rat, Monkey, Mouse
	PSMD2 (Proteasome 26S S2) Antibody (YA7816) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to PSMD2 (Proteasome 26S S2).

HY-P85152

	MAPK6/ERK3 Antibody (YA4844) MAPK6; ERK3; PRKM6; Mitogen-activated protein kinase 6; MAP kinase 6; MAPK 6; Extracellular signal-regulated kinase 3; ERK-3; MAP kinase isoform p97; p97-MAPK	WB, FC, ELISA	Human
	MAPK6/ERK3 Antibody (YA4844) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MAPK6/ERK3.

HY-P86934

	KPNB1 Antibody (YA6627) IMB 1 antibody; IMB1 antibody; IMB1_HUMAN antibody; Impnb antibody; Importin 90 antibody; Importin beta 1 antibody; Importin beta 1 subunit antibody; Importin subunit beta-1 antibody; Importin-90 antibody; IPOB antibody; IMB 1 antibody; IMB1 antibody; IMB1_HUMAN antibody; Impnb antibody; Importin 90 antibody; Importin beta 1 antibody; Importin beta 1 subunit antibody; Importin subunit beta-1 antibody; Importin-90 antibody; IPOB antibody; Karyopherin beta 1 antibody; Karyopherin beta 1 subunit antibody; Karyopherin subunit beta-1 antibody; KPNB 1 antibody; Kpnb1 antibody; MGC2155 antibody; MGC2156 antibody; MGC2157 antibody; NTF 97 antibody; NTF97 antibody; NTF97/Importin beta antibody; Nuclear factor p97 antibody; Pore targeting complex 97 kDa subunit antibody; PTAC97 antibody;	WB, IHC-P, IF-Tissue, IP	Human, Mouse, Rat
	KPNB1 Antibody (YA6627) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KPNB1.

HY-P83449

	MAPK6/ERK3 Antibody (YA3194) ERK3; PRKM6; p97MAPK; HsT17250; ERK-3	WB, IHC-P	Human, Mouse, Rat
	MAPK6/ERK3 Antibody (YA3194) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAPK6/ERK3.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-137342

SB1-G-187		PROTAC Synthesis
SB1-G-187 is a multi-target kinase PROTAC degrader with activity against various kinases including GCK, YES1, IRAK1 and LYN. SB1-G-187 induces degradation of target kinases via a *p97*-dependent pathway, and forms ternary complexes with CRBN and specific functional kinases. SB1-G-187 can be used in tumor-related research. (Pink: multi-target kinase ligand (HY-125142); Blue: CRBN ligand (HY-A0003); Black: linker) .

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