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Pathways Recommended:	Stem Cell/Wnt

Results for "

stem bark

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Apoptosis (1) ATP Synthase (1) Autophagy (2) Bacterial (7) COX (1) Dipeptidyl Peptidase (1) DNA/RNA Synthesis (1) Drug Derivative (7) DYRK (1) EBV (1) Endogenous Metabolite (1) Fungal (8) Glycosidase (1) HSV (1) Insecticide (1) Lipoxygenase (1) MDM-2/p53 (1) NO Synthase (1) Parasite (4) PPAR (2) Proteasome (1) RAR/RXR (2) Reactive Oxygen Species (ROS) (2) Reference Standards (5) Sirtuin (1) STAT (1) Tyrosinase (1)
By Research Areas:	Cancer (18) Cardiovascular Disease (3) Endocrinology (2) Infection (16) Inflammation/Immunology (13) Metabolic Disease (5) Neurological Disease (4)

By Targets:

Antibiotic (1)

Apoptosis (1)

ATP Synthase (1)

Autophagy (2)

Bacterial (7)

COX (1)

Dipeptidyl Peptidase (1)

DNA/RNA Synthesis (1)

Drug Derivative (7)

DYRK (1)

EBV (1)

Endogenous Metabolite (1)

Fungal (8)

Glycosidase (1)

HSV (1)

Insecticide (1)

Lipoxygenase (1)

MDM-2/p53 (1)

NO Synthase (1)

Parasite (4)

PPAR (2)

Proteasome (1)

RAR/RXR (2)

Reactive Oxygen Species (ROS) (2)

Reference Standards (5)

Sirtuin (1)

STAT (1)

Tyrosinase (1)

By Research Areas:

Cancer (18)

Cardiovascular Disease (3)

Endocrinology (2)

Infection (16)

Inflammation/Immunology (13)

Metabolic Disease (5)

Neurological Disease (4)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0163

Magnolol 5+ Cited Publications	RAR/RXR PPAR Autophagy Bacterial	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Magnolol, a natural lignan isolated from the stem bark of Magnolia officinalis, is a dual agonist of both RXRα and PPARγ, with EC₅₀ values of 10.4 µM and 17.7 µM, respectively.

HY-W013571

4-Isopropylbenzoic acid Cuminic acid; p-Isopropyl benzoic acid	Fungal	Infection
4-Isopropylbenzoic acid (Cuminic acid; p-Isopropyl benzoic acid) an aromatic monoterpenoid, is isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid exhibits antifungal activities. 4-Isopropylbenzoic acid is also a reversible and uncompetitive inhibitor of mushroom tyrosinase .

HY-N1581

Quassin Nigakilactone D	Parasite	Infection Endocrinology
Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits *P. falciparum* with an IC₅₀ of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity .

HY-N0821

Lithospermoside Griffonin	Others	Cancer
Lithospermoside (Griffonin) is a nature product isolated from the stem bark of Semiaquilegia adoxoides .

HY-N16690

3-Hydroxy-4-methoxycinnamaldehyde	Bacterial Fungal	Infection
3-Hydroxy-4-methoxycinnamaldehyde (compound 2) is a cinnamaldehyde from the stem bark of Flemingia paniculata Wall. 3-Hydroxy-4-methoxycinnamaldehyde exhibits antibacterial (both Gram-positive and Gram-negative) and antifungal activities (MIC = 12.5-50 μg/mL). 3-Hydroxy-4-methoxycinnamaldehyde can be used for microbial infections research .

HY-N0338

(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside	Others	Others
(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside is a lignan glycoside that can be isolated from the stem bark of Albizia julibrissin Durazz .

HY-N7625

N-Formylcytisine	Others	Metabolic Disease
N-Formylcytisine is a cytisine-type alkaloid from the stem bark of Maackia amurensis .

HY-N3175

Norlichexanthone Fusarindin	Others	Others
Norlichexanthone is a compound isolated from the stem bark of Kandelia candel (L.) Druce, Rhizophoraceae .

HY-N1652

2,3,8-Tri-O-methylellagic acid 3,3′,4-Tri-O-methylellagic acid	Others	Others
2,3,8-Tri-O-methylellagic acid is a terpenoids that can be isolated from the stem bark of Neoboutonia macrocalyx. 2,3,8-Tri-O-methylellagic acid is found to be 50 times more active than the parent ellagic acid .

HY-126535

Magnoloside B	Glycosidase	Metabolic Disease Cancer
Magnoloside B is an α-glucosidase inhibitor (IC₅₀=0.69 mM), which can be obtained from Magnolia officinalis stem bark. Magnoloside B shows moderate inhibitory activity against MGC-803 and HepG2 cells. Magnoloside B has the potential to study cancer and diabetes .

HY-N2857

Alpinumisoflavone	Others	Others
Alpinumisoflavone (compound 2) is a flavonoid derivative isolated from the stem bark of Erythrina lysistemon Hutch .

HY-N5125

2-Hydroxy-1-methoxyanthraquinone	Bacterial	Infection Inflammation/Immunology
2-Hydroxy-1-methoxyanthraquinone could be isolated from the stem bark of Morinda lucida Benth. (Rubiaceae) and possesses antibacterial activity .

HY-121211

Digitolutein	Parasite	Infection
Digitolutein is a natural product that can be isolated from the stem bark and the roots of Morinda lucida Benth. Digitolutein effectively inhibits the growth of *Plasmodium falciparum* with an IC₅₀ value of 12.92 μg/mL. Digitolutein can be used for the research of infection .

HY-N4048

Heudelotinone	Others	Cancer
Heudelotinone is a dinorditerpenoid that can be isolated from the stem bark and roots of Ricinodendron heudelotii. Heudelotinone shows cytotoxicity against SMMC-7721, A549 and Hela cells with IC₅₀s of 21.68, 16.04 and 10.67 μM, respectively .

HY-N16598

4''-O-Methylcatalposide	Others	Inflammation/Immunology
4''-O-Methylcatalposide (compound 7) is a glycoside from the stem bark of Catalpa ovata. 4''-O-Methylcatalposide exhibits peroxynitrite (ONOO ⁻)-scavenging activity with an IC₅₀ of 36.4 μM. 4''-O-Methylcatalposide can be used for anti-inflammatory research .

HY-N3149

(E)-2-Hydroxycinnamaldehyde	STAT Apoptosis Reactive Oxygen Species (ROS)	Cancer
(E)-2-Hydroxycinnamaldehyde is an aldehyde that can be separated from the stem bark of cinnamon. (E)-2-Hydroxycinnamaldehyde inhibits cell proliferation and induces apoptosis by inhibiting signal transduction of STAT3 and reactive oxygen species production. (E)-2-Hydroxycinnamaldehyde has antitumor activity .

HY-N3637

Cotoin	Others	Metabolic Disease
Cotoin is a natural product isolated from the stem bark of Garcinia virgate .

HY-N3554

Catechin-7-O-β-D-xylopyranoside (+)-Catechol 7-β-D-xylopyranoside	Others	Others
Catechin-7-O-β-D-xylopyranoside is an antioxidant compound with strong DPPH free radical scavenging ability. Catechin-7-O-β-D-xylopyranoside can be extracted from birch inner bark and nepeta stem bark .

HY-N2105

(-)-Dicentrine L-Dicentrine	Fungal Bacterial	Infection
(-)-Dicentrine is an aporphine alkaloid that can be isolated from the stem bark of Talauma arcabucoana. (-)-Dicentrine shows moderate growth inhibition against Staphylococcus aureus and Candida albicans .

HY-N3642

Cristacarpin Erythrabyssin I; Erythrabissin I	Others	Cancer
Cristacarpin can be extracted from the stem bark of Erythrina suberosa, promotes endoplasmic reticulum (ER) stress, leading to sublethal reactive oxygen species (ROS) production and ultimately cell death through senescence .

HY-N1251

Scholaricine	Others	Others
Scholaricine (compound 13 ) is an alkaloid isolated from the leaf and stem-bark extracts of Alstonia spatulata. Scholaricine reverse multidrug resistance in vincristine-resistant KB cells with an IC₅₀ value of 13.35 μM .

HY-N0163R

Magnolol (Standard)	Reference Standards RAR/RXR PPAR Autophagy Bacterial	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Magnolol (Standard) is the analytical standard of Magnolol. This product is intended for research and analytical applications. Magnolol, a natural lignan isolated from the stem bark of Magnolia officinalis, is a dual agonist of both RXRα and PPARγ, with EC50 values of 10.4 μM and 17.7 μM, respectively.

HY-N8265

Abyssinone V	HSV DNA/RNA Synthesis ATP Synthase	Infection
Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V can be isolated from the stem bark of Erythrina melanacantha. Abyssinone V possesses good pharmacodynamics properties. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity .

HY-W068783

(E)-3,4-(Methylenedioxy)cinnamic acid (E)-Piperonylprop-2-enoic acid	Endogenous Metabolite	Others
(E)-3,4-(Methylenedioxy)cinnamic acid is a cinnamic acid derivative obtained from the stem bark of Brombya platynema .

HY-N8134

2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one	Dipeptidyl Peptidase	Metabolic Disease
2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one is a natural product found in the leaves and stem bark of M. glabra. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one displays binding affinities with dipeptidyl peptidase-4 (DPP-4) and α-Amylase. 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one has potential antidiabetic activities .

HY-N1948

Mitoridine	Others	Others
Mitoridine is an indole alkaloid compound isolated from the stem bark of Rauwolfia cumminsii Stapf .

HY-W013571R

4-Isopropylbenzoic acid (Standard) Cuminic acid (Standard); p-Isopropyl benzoic acid (Standard)	Reference Standards Fungal	Infection
4-Isopropylbenzoic acid (Cuminic acid; p-Isopropyl benzoic acid) an aromatic monoterpenoid, is isolated from the stem bark of Bridelia retusa. 4-Isopropylbenzoic acid exhibits antifungal activities. 4-Isopropylbenzoic acid is also a reversible and uncompetitive inhibitor of mushroom tyrosinase .

HY-N6247

Fuscaxanthone C	Others	Others
Fuscaxanthone C is an xanthone isolated from the stem bark of Garcinia fusca .

HY-N3743

Erythrivarone A Dihydroalpinumisoflavone	Others	Others
Erythrivarone A is an isoflavone that can be isolated from the stem bark of Erythrina variegate .

HY-N12157

Noratherosperminine	Others	Others
Noratherosperminine is an alkaloid that can be isolated from the stem bark of Cryptocarya nigra .

HY-N8364

Evoxanthine	Others	Others
Evoxanthine is a compound that can be isolated from the stem bark of Pleiocarpa pycnantha .

HY-N1574

Puerol A	Others	Others
Puerol A is a Phenols product that can be isolated from the stem barks of Sophora japonica. .

HY-N9041

Pyranojacareubin	Others	Others
Pyranojacareubin is a Xanthones product that can be isolated from the stem barks of Calophyllum inophyllum. .

HY-123252

Kurchessine Sarcodinine	Others	Others
Kurchessine (Sarcodinine) is an alkaloid that can be isolated from the stem bark of Holarrhena antidysenterica .

HY-N12160

Erythrodiol diacetate	Others	Others
Erythrodiol diacetate (Compound 4) is a triterpenoid compound derived from Erythrina eriotriocha stem bark .

HY-N3374

Lochnerine 10-O-Methylsarpagine	Others	Others
Lochnerine is an indole alkaloid can be isolated from the stem bark extract of Alstonia macrophylla .

HY-107226

Crovatin	Others	Cancer
Crovatin, isolated from the stem bark of C. oblongifolius, shows anti-tumor effect .

HY-117164

Longicautadine	Others	Others
Longicautadine is a bisindole alkaloid that can be isolated from the root and stem bark of Strychnos nux vomica.

HY-N12996

Sitosterone	Others	Others
Sitosterone is a steroid that can be isolated from stem bark of syzygium aqueum. Sitosterone shows cytotoxicity .

HY-N1657

2,3-Dihydrohinokiflavone	Others	Others
2,3-Dihydrohinokiflavone is a flavonoid compound isolated from the stem bark of Rhus tripartite .

HY-121408

Hymexelsin Xeroboside	Others	Others
Hymexelsin (Xeroboside) is an apiose-containing scopoletin glycoside, that can be isolated from the stem bark of Hymenodictyon excelsum .

HY-N9219

2,5-Dihydroxyxanthone	Others	Others
2,5-Dihydroxyxanthone is a Xanthones product that can be isolated from the stem barks of Garcinia tetrandra .

HY-N1284

Seneganolide (-)-Seneganolide	Others	Others
Seneganolide (compound 1) is isolated from the stem bark of Khaya senegalensis. Seneganolide can be used as insect antifeedant .

HY-N1069

Wittifuran X	Others	Inflammation/Immunology
Wittifuran X is a 2-arylbenzofuran derivative, which can be isolated from the stem bark of Morus wittiorum .

HY-116631

Sarisan Asaricin	Fungal Insecticide	Infection
Sarisan (Asaricin) is a phenolic derivative with antifungal and insecticidal activity. Sarisan can be found in the stem bark of Ocotea opifera Mart. .

HY-N8994

3-Hydroxy-4',5-dimethoxystilbene	Others	Cancer
3-Hydroxy-4',5-dimethoxystilbene is a natural compound found in stem bark of Morus nigra L .

HY-N1641

1-O-Deacetylkhayanolide E Deacetylkhayanolide E	Others	Others
1-O-Deacetylkhayanolide E is a khayanolide, which can be isolated from the stem bark of African mahogany Khaya senegalensis .

HY-N15409

Epoxymurin A	Others	Others
Epoxymurin A is a compound that can be isolated from the stem bark of Annona Muricata. Epoxymurin A can be used in the study of the biosynthetic pathway of annonaceous acetogenins .

HY-N12803

2,5-Dihydroxy-7-methoxyflavanone	Others	Others
2,5-Dihydroxy-7-methoxyflavanone is a flavonoid compound that can be isolated from the stem bark of F. enghiana .

HY-N12968

R-(-)-Columbianetin	Others	Others
R-(-)-Columbianetin is a known coumarin isolated from the root and stem bark of Skimmia reevesiana collected in Taiwan, with specific chemical structure and biological activity .

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stem bark

Inhibitors & Agonists

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Natural
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