Chktide
Chktide is a synthetic peptide substrate applicable for activity assays of Chk1 kinase and cyk/CaMKII. Chktide contains the Ser53 phosphorylation site of Xenopus cyclin B2.
For research use only. We do not sell to patients.
- CAS No.: 289652-77-3
- Formula: C115H198N40O33S
- Molecular Weight:2701.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chktide serves as a standard synthetic substrate for Chk1 serine protein kinase assays and can be used for the quantitative detection of Chk1 catalytic activity[1].
Chktide contains the Ser53 phosphorylation site of Xenopus cyclin B2, and upon phosphorylation, it induces a prophase-like premature phenotype in fibroblasts[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 289652-77-3
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Molecular Weight 2701.12
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Formula C115H198N40O33S
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Sequence
Lys-Lys-Lys-Val-Ser-Arg-Ser-Gly-Leu-Tyr-Arg-Ser-Pro-Ser-Met-Pro-Glu-Asn-Leu-Asn-Arg-Pro-Arg
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Sequence Shortening
KKKVSRSGLYRSPSMPENLNRPR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1].
Walker M, et al. Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity. Oncogene. 2009 Jun 18;28(24):2314-23.
[Content Brief]
[2]. Stevens I, et al. Identification of cyk, a cyclin B2 kinase, as a novel calcium/calmodulin-dependent protein kinase II and its role during Xenopus laevis oocyte maturation. Experimental cell research. 1999 Nov 01;252(2):303-18. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Chktide Related Classifications
HY-P5961 Related Classifications
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