Sirt2-IN-6
Sirt2-IN-6 (compound 24a) potent and selective inhibitor of SIRT2, with an IC50 of 0.815 μM. Sirt2-IN-6 can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 2243151-81-5
- Formula: C26H26N6O3S
- Molecular Weight:502.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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SIRT2 0.815 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H441 | IC50 |
3.93 μM
Compound: 24a
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Antiproliferative activity against human NCI-H441 cells after 72 hrs by MTT assay
Antiproliferative activity against human NCI-H441 cells after 72 hrs by MTT assay
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[PMID: 29957526] |
Chemical Information
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CAS No. 2243151-81-5
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Molecular Weight 502.59
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Formula C26H26N6O3S
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SMILES
O=C(C1=CN(C)N=C1)NC2=CC=C(C=C2)OCC3=CC(NC(CSC4=NC(C)=CC(C)=N4)=O)=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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