Speranskoside
Speranskoside is a dual COX-2/15-LOX inhibitor with a COX-2 IC50 of 2.62 μg/mL and a 15-LOX IC50 of 5.51 μg/mL. Speranskoside can be used for the research of gastric ulcers.
For research use only. We do not sell to patients.
- CAS No.: 219917-70-1
- Formula: C30H28O12
- Molecular Weight:580.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
COX-2 2.62 μg/mL (IC50) |
15-LOX 5.51 μg/mL (IC50) |
In Vitro
Speranskoside (Compound E7) (0.25-500 μg/mL) potently inhibits the COX-2 enzyme, with an IC50 value of 2.62 μg/mL[1].
Speranskoside (0.25-500 μg/mL) potently inhibits the 15-LOX enzyme, with an IC50 value of 5.51 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 219917-70-1
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Molecular Weight 580.54
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Formula C30H28O12
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SMILES
O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)OC(/C=C/C4=CC=C(C=C4)O)=O)CO)C=C2O[C@H](C5=CC=C(C=C5)O)C1
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Speranskoside Related Classifications
HY-N18218 Related Classifications
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