Microbial Metabolite Standards

Thymidine-5'-monophosphate (TMP) disodium salt (Standard) is the analytical standard of Thymidine-5'-monophosphate disodium salt (HY-128738). This product is intended for research and analytical applications. Thymidine-5'-monophosphate (TMP) disodium salt is a key nucleotide in pyrimidine metabolism, and its kinase activity can be competitively inhibited by 5'-fluorothymidine. The level of Thymidine-5'-monophosphate disodium salt is closely associated with acute kidney injury.

Undecanoic acid (Standard) (Undecanoate (Standard)) is the analytical standard of Undecanoic acid (HY-W004282). This product is intended for research and analytical applications. Undecanoic acid is a monocarboxylic acid with antifungal property. Undecanoic acid inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum.

DL-Glutamine (Standard) ((±)-Glutamine (Standard); DL-Gl (Standard)) is the analytical standard of DL-Glutamine (HY-B1346). This product is intended for research and analytical applications. DL-Glutamine ((±)-Glutamine; DL-Gl) is an amino acid metabolite. DL-Glutamine is a plasma metabolic biomarker associated with Treg/Th17 balance in an OVA-induced eosinophilic asthma mouse model. DL-glutamine positively correlates with muscle quality parameters such as muscle water-holding capacity and shear force, and negatively correlates with oxidative stress markers and apoptotic gene expression. DL-Glutamine is associated with periodontal pathogens and oral microbial communities in saliva/serum. DL-Glutamine can be used in research related to asthma, muscle quality, and periodontal disease.

DT2216 (Standard) is the analytical standard of DT2216 (HY-130604). This product is intended for research and analytical applications. DT2216 is a potent and selective BCL-XL (Bcl-2 family member) degrader based on PROTAC technology. DT2216 causes effective degradation of BCL-XL protein by recruiting Von Hippel-Lindau (VHL) E3 ubiquitin ligase. DT2216 inhibits various BCL-XL-dependent leukemia and cancer cells but considerably less toxic to platelets.

(-)-3-Dehydroshikimic acid (Standard) (3-DHS (Standard)) is the analytical standard of (-)-3-Dehydroshikimic acid (HY-N9934). This product is intended for research and analytical applications. (-)-3-Dehydroshikimic acid (3-DHS) is an intermediate of the Shikimate pathway. (-)-3-Dehydroshikimic acid is found in vegetables and fruits. (-)-3-Dehydroshikimic acid accumulates in bacterial mutants, serves as a precursor of aromatic metabolites, and competitively interferes with the growth response of mutant bacteria to Shikimic acid (HY-N0130). (-)-3-Dehydroshikimic acid exhibits weak antioxidant activity in liposomes and corn oil oil-in-water emulsions.

4-Nitrocatechol (Standard) is the analytical standard of 4-Nitrocatechol (HY-W066890). This product is intended for research and analytical applications. 4-Nitrocatechol is a Lipoxygenase inhibitor. 4-Nitrocatechol can serve as a ligand to stabilize the formation of metal complexes. As a (+) MALDI matrix, 4-Nitrocatechol significantly enhances the MALDI-MS detection and imaging of low-molecular-weight compounds in animal and plant tissue sections.

Benzamide (Standard) is the analytical standard of Benzamide. This product is intended for research and analytical applications. Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature.

Hydroxyacetone is a dehydration product of glycerol. Hydroxyacetone is a platform for the electrocatalytic synthesis of acetone, 1,2-propanediol and 2-propanol. Hydroxyacetone can also be used as a glycerol substitute for electrocatalytic hydrogenation and hydrodeoxygenation processes.

Hydrocinnamic acid (Standard) is the analytical standard of Hydrocinnamic acid. This product is intended for research and analytical applications. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities.

2,6-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,6-Dihydroxybenzoic acid (HY-Y0801). This product is used for research and analytical applications. 2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater.

7-Methylxanthine (Standard) is the analytical standard of 7-Methylxanthine. This product is intended for research and analytical applications. 7-Methylxanthine is an orally active methyl derivative of xanthine and a non-selective adenosine receptor antagonist. 7-Methylxanthine is also one of the purine components of human urinary calculi. 7-Methylxanthine has anti-myopia activity.

5-Methyluridine (Standard) is the analytical standard of 5-Methyluridine. This product is intended for research and analytical applications. 5-Methyluridine is a is an endogenous methylated nucleoside found in human fluids.

cis,cis-Muconic acid (Standard) is an analytical standard for cis,cis-Muconic acid (HY-W000800). This product is used for research and analytical applications. cis,cis-Muconic acid is a dicarboxylic acid produced by Saccharomyces cerevisiae. cis,cis-Muconic acid shows pH-dependent toxicity against Saccharomyces cerevisiae CEN.PK113-7D. cis,cis-Muconic acid can be used as intermediate for the production of various plastics and polymers.

Furaneol (Standard) is the analytical standard of Furaneol. This product is intended for research and analytical applications. Furaneol is mainly isolated from American grape (Vitis labrusca) and its hybrid grape. Furaneol is an important aroma compound in fruits and contribute to the strawberry-like note in some wines.

Tropine (Standard) is the analytical standard of Tropine (HY-N7061). This product is intended for research and analytical applications. Tropine is a tropane alkaloid. Tropine serves as an important intermediate for the synthesis of anticholinergics and bronchodilators such as Atropine (HY-B1205) and Scopolamine (HY-N0296).

Orsellinic acid (Standard) is an analytical standard of Orsellinic acid (HY-N3126). This product is intended for research and analytical applications. Orsellinic acid is a Benzoic acid (HY-N0216) derivative. Orsellinic acid can be isolated from Chaetomium globosum endophytic on Ephedra fasciculata (Mormon tea). Orsellinic acid blocks PAF-mediated Apoptosis, inhibits caspase-3/7 activation, and PARP cleavage. Orsellinic acid can be used in research of neurons and various tumors (non-small cell lung cancer, breast cancer, neuroblastoma, pancreatic cancer).

Allitol (Allodulcitol) (Standard) is the analytical standard of Allitol (HY-N2840). This product is intended for research and analytical applications. Allitol is an orally active rare sugar alcohol found in Itea virginica L, Tylopilus plumbeoviolaceus. Allitol has anti-obesity and hypoglycaemic activities. Allitol reduces carcass and total body fat mass, increases cecal weight, surface area, and short-chain fatty acid production, and upregulates cecal microbial enzymes linked to butyrate metabolism. Allitol can be used for the researches of obesity and diabetes.

Vanillyl alcohol (Standard) is the analytical standard of Vanillyl alcohol (HY-N2067). This product is intended for research and analytical applications. Vanillyl alcohol (p-(Hydroxymethyl)guaiacol) is an orally active phenolic alcohol. Vanillyl alcohol reduces ROS generation. suppresses Bax, increases Bcl-2. Vanillyl alcohol has anti-angiogenic, anti-inflammatory, anti-nociceptive and neuroprotective effects. Vanillyl alcohol is used as a flavoring agent in foods and beverages.

L-Aspartic aicd sodium (Standard) (Sodium L-aspartate (Standard)) is the analytical standard of L-Aspartic aicd sodium (HY-N0666C). This product is intended for research and analytical applications. L-Aspartic acid sodium (Sodium L-aspartate) is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid sodium has no independent analgesic activity. L-Aspartic acid sodium can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid sodium regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid sodium promotes burst firing of central neurons. L-Aspartic acid sodium can be used in studies related to cerebral ischemia and epilepsy.

2,5-Dimethylpyrazine (Standard) is the analytical standard of 2,5-Dimethylpyrazine. This product is intended for research and analytical applications. 2,5-Dimethylpyrazine is an endogenous metabolite.