1. PROTAC
  2. Ligands for E3 Ligase
  3. Thalidomide-5,6-Cl

Thalidomide-5,6-Cl is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-Cl can be connected to the ligand for protein by a linker to form PROTACs.

For research use only. We do not sell to patients.

Thalidomide-5,6-Cl Chemical Structure

Thalidomide-5,6-Cl Chemical Structure

CAS No. : 2648939-40-4

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Description

Thalidomide-5,6-Cl is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-Cl can be connected to the ligand for protein by a linker to form PROTACs.

In Vitro

Thalidomide-5,6-Cl is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5,6-Cl can be connected to the ligand for protein by a linker to form PROTACs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

327.12

Formula

C13H8Cl2N2O4

CAS No.
SMILES

O=C1NC(C(CC1)N2C(C3=CC(Cl)=C(C=C3C2=O)Cl)=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Thalidomide-5,6-Cl Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Thalidomide-5,6-Cl
Cat. No.:
HY-139547
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