TLR7 agonist 4
Based on 1 Customer Validation
TLR7 agonist 4 is a TLR7 agonist with pro-inflammatory cytokine-stimulating activity. TLR7 agonist 4 modulates TLR7 activity to stimulate the production of pro-inflammatory cytokines. TLR7 agonist 4 stimulates mouse bone marrow-derived macrophages to produce the pro-inflammatory cytokine TNFα. TLR7 agonist 4 can be conjugated with antibodies to form conjugates. TLR7 agonist 4 is applicable to cancer research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.87%
- No. CAS: 2413016-42-7
- Fòrmula: C23H34N6O3
- Peso molecular:442.55
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Almacenamiento:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Actividad biológica
Descripciòn
IC50 & Target
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TLR7 4.3 nM (EC50) |
In Vitro
TLR7 agonist 4 (Compound 1.2) (0-1000 nM) potently induces TNFα production in mouse bone marrow-derived macrophages, with an EC50 of 4.3 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2413016-42-7
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Appearance Solid
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Peso molecular 442.55
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Fòrmula C23H34N6O3
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Color White to off-white
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SMILES
O=C(C(C)(C)N)NCCOC(C)(CN1C(COCC)=NC2=C1C3=C(C=CC=C3)N=C2N)C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureza y Documentación
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Ficha de datos (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TLR7 agonist 4 Related Classifications
HY-145961 Related Classifications
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