Tuberactinomycin-O
Tuberactinomycin-O is a peptide antibiotic belonging to the tuberactinomycin family. Tuberactinomycin-O inhibits the growth of various bacteria, including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Mycobacterium ATCC 607. Tuberactinomycin-O exhibits acute toxicity in male mice when administered intravenously. Tuberactinomycin-O can be used in the research of tuberculosis.
For research use only. We do not sell to patients.
- CAS No.: 33137-73-4
- Formula: C25H43N13O9
- Molecular Weight:669.69
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Tuberactinomycin-O (24 h) inhibits the growth of multiple bacterial strains in vitro, with the highest potency against Bacillus subtilis PCI 219 (MIC 3.2 mcg/mL) and Mycobacterium ATCC 607 (MIC 6.3 mcg/mL), and the lowest potency against Staphylococcus aureus FDA 209 P and Sarcina lutea ATCC 1001 (MIC 100 mcg/mL)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mice (male)[1]
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Dosage:/
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Administration:i.v.; single dose
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Result:Determined an acute median lethal dose (LD50) of 370 mg/kg.
Chemical Information
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CAS No. 33137-73-4
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Molecular Weight 669.69
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Formula C25H43N13O9
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SMILES
O=C1[C@](NC(/C(NC([C@@H](NC([C@@H](NC([C@H](CN1)NC(C[C@@H](N)CCCN)=O)=O)CO)=O)CO)=O)=C/NC(N)=O)=O)([H])[C@]2([H])NC(N)=NCC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tuberactinomycin-O Related Classifications
HY-182535 Related Classifications
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- Tuberactinomycin-O
- 33137-73-4
- Antibiotic
- Bacterial
- Staphylococcus aureus
- human tubercle bacilli H37Rv
- Bacillus subtilis PCI 219
- tubercle bacilli
- Pseudomonas aeruginosa
- Escherichia coli
- Streptomyces griseoverticillatus var. tuberacticus
- male mice
- Sarcina lutea ATCC 1001
- Mycobacterium ATCC 607
- Inhibitor
- inhibitor
- inhibit