VinSpinIn
VinSpinIn is a Spindlin1 inhibitor (KD: 9.9 nM for SPIN149-262). VinSpinIn is a chemical probe for tudor domain of Spindlin1. VinSpinIn can be used to study chromatin function.
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- CAS. Nr.: 2380021-98-5
- Formel: C42H58N8O4
- Molecular Weight:738.96
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
KD: 9.9 nM for SPIN149-262[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U2OS | EC50 |
270 nM
Compound: 35
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Inhibition of C-terminal Halotag-histone 3.3 tagged SPIN1 (unknown origin) transfected in human U2OS cells cotransfected with nano-luciferase at 1 uM using NanoBRET Nano-Glo substrate as substrate incubated for 24 hrs by NanoBRET assay
Inhibition of C-terminal Halotag-histone 3.3 tagged SPIN1 (unknown origin) transfected in human U2OS cells cotransfected with nano-luciferase at 1 uM using NanoBRET Nano-Glo substrate as substrate incubated for 24 hrs by NanoBRET assay
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[PMID: 31550156] |
Chemical Information
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CAS. Nr. 2380021-98-5
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Molecular Weight 738.96
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Formel C42H58N8O4
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SMILES
CC1(C)C(N)=NC2=CC(OCCCN3CC(C=CC(OCCC4=CN(CC(N5CCC(CCN6CCCC6)CC5)=O)N=N4)=C7)=C7C3)=C(OCC8CC8)C=C21
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
VinSpinIn Related Classifications
HY-114207 Related Classifications
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