VU0469650 hydrochloride
VU0469650 hydrochloride is a brain-penetrant negative allosteric modulator of metabotropic glutamate receptor 1 (mGluR1). VU0469650 hydrochloride inhibits glutamate-induced calcium flux in cells expressing human mGluR1 (IC50= 99 nM). VU0469650 hydrochloride is promising for research of central nervous system diseases such as anxiety, addiction, and epilepsy.
For research use only. We do not sell to patients.
- Formula: C22H29ClN4O
- Molecular Weight:400.94
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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mGluR1 |
Chemical Information
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Molecular Weight 400.94
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Formula C22H29ClN4O
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SMILES
O=C(N1[C@@H](CN(C2=C(N=CC=C2)C#N)CC1)C)C34C[C@H](C5)C[C@H](C[C@H]5C4)C3.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)