1. GPCR/G Protein
    Neuronal Signaling
  2. mGluR
  3. VU6001376

VU6001376 

Cat. No.: HY-112814
Handling Instructions

VU6001376 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4 PAM) with an EC50 of 50.1 nM.

For research use only. We do not sell to patients.

VU6001376 Chemical Structure

VU6001376 Chemical Structure

CAS No. : 1968546-34-0

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Description

VU6001376 is a potent and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4 PAM) with an EC50 of 50.1 nM[1].

IC50 & Target[1]

mGlu4

50.1 nM (EC50)

Molecular Weight

400.41

Formula

C₁₈H₁₄F₂N₆OS

CAS No.

1968546-34-0

SMILES

O=C(NC1CC(F)(F)C1)C2=NSC3=CC(NC4=NNC5=C4N=CC=C5)=CC=C32

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

VU6001376VU 6001376VU-6001376mGluRMetabotropic glutamate receptorsInhibitorinhibitorinhibit

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VU6001376
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