2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-112142
    AB-423 1572510-80-5 99.31%
    AB-423 is an inhibitor of HBV capsid assembly, and potent inhibits HBV replication with EC50/EC90 of 0.08-0.27 μM/0.33-1.32 μM in cells.
    AB-423
  • HY-112328
    Fascaplysin 114719-57-2
    Fascaplysin is an antimicrobial and cytotoxic red pigment, that can come from the marine sponge (Fascaplysinopsis sp.). Fascaplysin has been synthesized in seven steps from indole (65% yield). Fascaplysin can induces apoptosis and autophagy in human leukemia HL-60 cells. Fascaplysin shows anti-tumor activity.
    Fascaplysin
  • HY-112420
    EGFR/ErbB-2-IN-2 179248-61-4 99.45%
    EGFR/ErbB-2-IN-2 is a EGFR and ErbB inhibitor with IC50s of 0.017 μM, 0.08 μM, 1.91 μM for EGFR, ErbB-2 and ErbB-4.
    EGFR/ErbB-2-IN-2
  • HY-113715
    Niclofolan 10331-57-4 99.46%
    Niclofolan (BAY 9015) is an orally active anthelmintic agent. Niclofolan can be used in the research of parasite infection.
    Niclofolan
  • HY-113735
    Cephapirin hemibenzathine 97468-37-6 99.69%
    Cephapirin hemibenzathine is an intrauterine-administered, long-acting cephalosporin antibiotic suitable for the anaerobic environment of the postpartum uterus. Cephapirin hemibenzathine effectively improves the recovery of postpartum buffaloes with subclinical endometritis (SCE) and enhances their reproductive performance. Cephapirin hemibenzathine can be used for the study of subclinical endometritis in postpartum buffaloes.
    Cephapirin hemibenzathine
  • HY-113764
    N-Butanoyl-DL-homoserine lactone 98426-48-3 98.0%
    N-Butanoyl-DL-homoserine lactone ((Rac)-C4-HSL) is a racemic mixture of N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.
    N-Butanoyl-DL-homoserine lactone
  • HY-114818
    4-(tert-Butyl)-benzhydroxamic Acid 62034-73-5 99.69%
    4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively. 4-(tert-Butyl)-benzhydroxamic Acid reduces the production of the virulence factor pyocyanin in P. aeruginosa with an IC50 of 87.2 μM.
    4-(tert-Butyl)-benzhydroxamic Acid
  • HY-116993
    N-(Hydroxymethyl)nicotinamide 3569-99-1 99.82%
    N-(Hydroxymethyl)nicotinamide is an antimicrobic agent.
    N-(Hydroxymethyl)nicotinamide
  • HY-117319
    Indolmycin 21200-24-8 99.90%
    Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA synthetase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity.
    Indolmycin
  • HY-118099
    Florfenicol amine hydrochloride 108656-33-3 98.61%
    Florfenicol amine hydrochloride is a metabolite of Florfenicol (HY-B1374). Florfenicol inhibits bacterial protein synthesis by binding to 50S and 70S subunits in the ribosome to abolish the activity of peptidyltransferase. Florfenicol, is a veterinary antibiotic, can be used in aquaculture to control susceptible bacterial diseases.
    Florfenicol amine hydrochloride
  • HY-118921
    Ovatodiolide 3484-37-5 98.93%
    Ovatodiolide is a compound that can be isolated from Anisomeles indica. Ovatodiolide has anti-bacterial and anti-inflammatory properties. Ovatodiolide also has anti-cancer activity that induces cell cycle G2/M arrest and apoptosis via a ROS-dependent ATM/ATR signaling pathways.
    Ovatodiolide
  • HY-119500
    Ilimaquinone 71678-03-0 ≥99.0%
    Ilimaquinone, a marine sponge metabolite, displays anticancer activity via GADD153-mediated pathway. Ilimaquinone can induce vesiculation of the Golgi apparatus. Ilimaquinone exerts anti-HIV, anti-microbial, anti-inflammatory, and effects.
    Ilimaquinone
  • HY-119614
    Niridazole 61-57-4 98.75%
    Niridazole is an anaerobic and microaerophilic bacterial inhibitor with IC50 values ranging from 0.0037 to 1.0 μg/mL.
    Niridazole
  • HY-119821
    Terphenyllin 52452-60-5
    Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has significant α-glucosidase inhibitory activity.
    Terphenyllin
  • HY-120338
    RYL-552 1801444-56-3 99.09%
    RYL-552, a mitochondrial electron transport chain (ETC) inhibitor, is a P. falciparum NADH dehydrogenase 2 (PfNDH2) inhibtor.
    RYL-552
  • HY-120397
    Bis-propargyl-PEG4 159428-42-9
    Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers. Bis-propargyl-PEG4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Bis-propargyl-PEG4
  • HY-12082A
    GSK369796 Dihydrochloride 1010411-21-8 99.56%
    GSK369796 Dihydrochloride is an affordable and effective antimalarial and inhibits hERG potassium ion channel repolarization with an IC50 of 7.5 μM.
    GSK369796 Dihydrochloride
  • HY-121060
    Gloxazone 2507-91-7 99.66%
    Gloxazone is an effective anaplasmacide.
    Gloxazone
  • HY-121144
    Cefazedone 56187-47-4 99.89%
    Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria.
    Cefazedone
  • HY-121300
    Kendomycin 183202-73-5 98.00%
    Kendomycin ((−)-TAN 2162) is a polyketide antibiotic with remarkable antibacterial and cancer cells cytotoxic activities. Kendomycin tends to be bacteriostatic rather than bactericidal and inhibits the growth of the methicillin-resistant Staphylococcus aureus (MRSA) strain COL at a low concentration (MIC of 5 μg/mL). Kendomycin is a potent antagonist of the endothelin receptor and a calcitonin receptor agonist which plays its role as an anti-osteoporotic agent.
    Kendomycin
Cat. No. 상품명 / Synonyms Application Reactivity