Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
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Drug Metabolite Related Products (2022)
Related Products (2022)
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Antibodies (1)
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Related Compound Screening Libraries (1)
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7-Hydroxycannabidiol
0 ImagesCat. No.: HY-W775325CAS No.: 50725-17-2Synonyms: 7-OH-CBD7-Hydroxycannabidiol (7-OH-CBD) is the metabolite of cannabidiol, which could be found in human serum and saliva.
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5-Hydroxythiabendazole (Standard)
0 ImagesCat. No.: HY-116787RCAS No.: 948-71-0Synonyms: 5-OHTBZ (Standard)5-Hydroxythiabendazole (Standard) is the analytical standard of 5-Hydroxythiabendazole. This product is intended for research and analytical applications. 5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure.
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N-Desmethyl dimethoate
0 ImagesN-Desmethyl dimethoate is a metabolite of Dimethoate (HY-B1946). N-Desmethyl dimethoate undergoes hydrolytic degradation in common bean plants. Dimethoate is an organophosphorus insecticide and acaricide.
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Desmethyl Erlotinib-d4
0 ImagesCat. No.: HY-13256ASCAS No.: 1216420-11-9Desmethyl Erlotinib-d4 is the deuterium labeled Desmethyl Erlotinib. Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor. Desmethyl Erlotinib-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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3-Hydroxy-4-methyl-2(5H)-thiophenone
0 ImagesCat. No.: HY-Z7429CAS No.: 34876-35-23-Hydroxy-4-methyl-2(5H)-thiophenone (compound 18) is a pyrazine derivative and the major acidic degradation product of Cephalexin (HY-B0200).
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PB-22 N-(5-Hydroxypentyl)-3-carboxyindole metabolite
0 ImagesCat. No.: HY-172055CAS No.: 1459236-34-0PB-22 N-(5-Hydroxypentyl)-3-carboxyindole metabolite is a metabolite of PB-22. PB-22 is a cannabinoid.
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W36017 (Standard)
0 ImagesCat. No.: HY-145482RCAS No.: 21236-54-48-Hydroxyquinoline (hemisulfate) (Standard) is the analytical standard of 8-Hydroxyquinoline (hemisulfate). This product is intended for research and analytical applications. 8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
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4-Carboxypyrazole (Standard)
0 Images4-Carboxypyrazole (Standard) is the analytical standard of 4-Carboxypyrazole (HY-W002065). This product is intended for research and analytical applications. 4-Carboxypyrazole is a pyrazole metabolite and a human liver alcohol dehydrogenase ligand. It is a metabolite of 4-methylpyrazole in mice and rats and does not inhibit the enzyme when methanol is used as a substrate. 4-Carboxypyrazole can be used in studies related to alcohol dehydrogenase metabolism.
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N-Acetyl-S-(2-cyanoethyl)-L-cysteine ammonium
0 ImagesCat. No.: HY-W714541CAS No.: 168208-30-8N-Acetyl-S-(2-cyanoethyl) -L-cysteine ammonium salt is the urinary metabolite of acrylamide in vivo.
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17(R)-Resolvin D3
0 ImagesCat. No.: HY-139232CAS No.: 1427475-53-3Synonyms: 17(R)-RvD317(R)-Resolvin D3 is a metabolite of docosahexaenoic acid (DHA). 17(R)-Resolvin D3 has anti-inflammatory activity.
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Desmethyl Levofloxacin hydrochloride
0 ImagesCat. No.: HY-W740165CAS No.: 2254176-11-7Desmethyl Levofloxacin hydrochloride is a metabolite of Levofloxacin (HY-B0330). Levofloxacin is a synthetic fluoroquinolone antibiotic that inhibits the supercoiling activity of bacterial DNA gyrase and prevents DNA replication.
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S 8849-1-d4 free base
0 ImagesCat. No.: HY-166341SCAS No.: 1330822-91-7Synonyms: Tianeptine metabolite MC5-d4S 8849-1-d4 (free base) (Tianeptine metabolite MC5-d4) is deuterium labeled S 8849-1 (free base). S 8849-1 (free base) (Tianeptine metabolite MC5) is a Tianeptine (HY-90003) metabolite that is found in plasma. The mean elimination half-lives of S 8849-1 (free base) is 7.53 h in rats. S 8849-1 (free base) is promising for research of antidepressants.
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4-Hydroperoxy cyclophosphamide (Standard)
0 ImagesCat. No.: HY-117433RCAS No.: 39800-16-34-Hydroperoxy cyclophosphamide (Standard) is the analytical standard of 4-Hydroperoxy cyclophosphamide (HY-117433). This product is intended for research and analytical applications. 4-Hydroperoxy cyclophosphamide is the active metabolite form of the precursor Cyclophosphamide. 4-Hydroperoxy cyclophosphamide cross-links DNA to induce T cell apoptosis independent of caspase receptor activation, and can activate the mitochondrial death pathway by producing reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide can be used in the study of rheumatoid arthritis and autoimmune diseases.
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Disulfoton sulfone
0 ImagesCat. No.: HY-W338799CAS No.: 2497-06-5Disulfoton sulfone is a metabolite of the organophosphorus pesticide Disulfoton.
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Salbutamol methyl ether
0 ImagesCat. No.: HY-Z6663CAS No.: 870076-72-5Salbutamol methyl ether is a derivative of Salbutamol (HY-B1037) used as an immunohapten to obtain antibodies.
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(R)-Amino-N-benzyl-3-methoxypropionamide (Standard)
0 Images(R)-Amino-N-benzyl-3-methoxypropionamide (Standard) is the analytical standard of (R)-Amino-N-benzyl-3-methoxypropionamide. This product is intended for research and analytical applications. (R)-Amino-N-benzyl-3-methoxypropionamide is a stable intermediate of Lacosamide (an antiepileptic drug).
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Ethyl mycophenolate
0 ImagesCat. No.: HY-137238CAS No.: 32483-51-5Ethyl mycophenolate is a potential impurity found in commercial preparations of the mycophenolic acid prodrug mycophenolate mofetil.
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Norfluoxetine oxalate
0 ImagesCat. No.: HY-135556ACAS No.: 107674-50-0Norfluoxetine oxalate is the active metabolite of the antidepressant Fluoxetine (HY-B0102); it is also a TREK-2 K2P potassium channel inhibitor. Norfluoxetine oxalate exhibits neuroimmunological activity, induces apoptosis in primary microglial cells, and inhibits the release of pro-inflammatory factors. Norfluoxetine oxalate inhibits high-threshold voltage-gated Ca2+ currents in neurons with an EC50 of 20.4 μM. Norfluoxetine oxalate can be used in research related to depression, ischemic stroke, and epilepsy.
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Aristolochic acid Ia
0 ImagesCat. No.: HY-N8500CAS No.: 38965-71-8Aristolochic acid Ia is an oxidative metabolite of aristolochic acid I, which can be used to study the detoxification pathway of aristolochic acid metabolism.
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6,15-Diketo-13,14-dihydro prostaglandin F1α
0 ImagesCat. No.: HY-W436495CAS No.: 63983-53-9Synonyms: 6,15-Diketo-13,14-dihydro-PGF1α6,15-Diketo-13,14-dihydro prostaglandin F1α (6,15-Diketo-13,14-dihydro-PGF1α) is a metabolite of prostacyclin (PGI2). 6,15-Diketo-13,14-dihydro prostaglandin F1α enhances intracellular cAMP and cholesterol metabolism in bovine arterial smooth muscle cells.
