ERK Activator

ERK Activators (22):

Cat. No.	Product Name	Effect	Purity

HY-100489

TBHQ	Activator	99.76%
TBHQ (tert-Butylhydroquinone) is a widely used Nrf2 activator, protects against Doxorubicin (DOX)-induced cardiotoxicity through activation of Nrf2.

HY-108635

C16-PAF	Activator	99.48%
C16-PAF (PAF (C16)), a phospholipid mediator, is a platelet-activating factor and ligand for PAF G-protein-coupled receptor (PAFR).

HY-104047

LM22B-10	Activator	99.72%
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo.

HY-W010907

Pamoic acid disodium	Activator	≥98.0%
Pamoic acid disodium is a potent GPR35 agonist with an EC₅₀ value of 79 nM.

HY-137977

DMU-212	Activator	99.91%
DMU-212 is a methylated derivative of Resveratrol (HY-16561), with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities.

HY-N8418

Cearoin	Activator	≥98.0%
Cearoin increases autophagy and apoptosis through the production of ROS and the activation of ERK.

HY-101364

CHPG	Activator	≥99.0%
CHPG is a selective mGluR5 agonist, and attenuates SO₂-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells.

HY-101364A

CHPG sodium salt	Activator	99.17%
CHPG sodium salt is a selective mGluR5 agonist, and attenuates SO₂-induced oxidative stress and inflammation through TSG-6/NF-κB pathway in BV2 microglial cells.

HY-N8211

Gypenoside L	Activator	99.42%
Gypenoside L is a saponin that can be found in Gynostemma pentaphyllum.

HY-129566

Withanolide B	Activator	≥99.0%
Withanolide B is an active component of W.

HY-139192

NMDAR/TRPM4-IN-2	Activator	98.64%
NMDAR/TRPM4-IN-2 (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor.

HY-109556

Insulin Detemir	Activator
Insulin Detemir is an artificial insulin, shows effect on controlling blood sugar levels.

HY-150795

SY-LB-35	Activator
SY-LB-35 is a potent bone morphogenetic protein (BMP) receptor agonist.

HY-P4159A

Endothelin-1 (1-31) (Human) TFA	Activator
Endothelin-1 (1-31) (Human) TFA is a potent vasoconstrictor and hypertensive agent.

HY-101446

HIOC	Activator
HIOC is a potent and selective activator of TrkB (tropomyosin related kinase B) receptor.

HY-113599

Isoprocurcumenol	Activator
Isoprocurcumenol is a guaiane type sesquiterpene, that can be isolated from Curcuma comosa.

HY-N3711

Dehydrocrenatine	Activator
Dehydrocrenatidine, a β-carboline alkaloid that can be isolated from Picrasma quassioides.

HY-P4159

Endothelin-1 (1-31) (Human)	Activator
Endothelin-1 (1-31) (Human) is a potent vasoconstrictor and hypertensive agent.

HY-142066

4′-Demethylnobiletin	Activator
4′-Demethylnobiletin is a bioactive metabolite that activates the PKA/ERK/CREB signaling pathway, enhances CRE-mediated transcription in hippocampal neurons, and reverses memory impairment associated with NMDA receptor antagonism by stimulating ERK signaling.

HY-139192A

NMDAR/TRPM4-IN-2 free base	Activator	≥98.0%
NMDAR/TRPM4-IN-2 free base (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor.

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