Reference Standards
Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.
-
Reference Standards Related Products (11771)
Related Products (11771)
-
PD146176 (Standard)
0 ImagesSynonyms: NSC168807 (Standard)PD146176 (Standard) is the analytical standard of PD146176. This product is intended for research and analytical applications. PD146176 (NSC168807), a 15-Lipoxygenase (15-LO) inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197 nM, IC50=0.54 μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.
-
Cedazuridine (Standard)
0 ImagesSynonyms: E7727 (Standard)Cedazuridine (Standard) is the analytical standard of Cedazuridine. This product is intended for research and analytical applications. Cedazuridine (E7727) (Compound 7a) is an orally active cytidine deaminase (CDA) inhibitor with an IC50 value of 0.4 μM. Cedazuridine can be used for cancer research.
-
BIBO3304 (Standard)
0 ImagesCat. No.: HY-107725RCAS No.: 191868-14-1BIBO3304 (Standard) is the analytical standard of BIBO3304 (HY-107725). This product is intended for research and analytical applications. BIBO3304, a chemical probe, is a potent, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist, with subnanomolar affinity for both the human and the rat Y1 receptor (IC50=0.38 and 0.72 nM, respectively).
-
POPG sodium (Standard)
0 ImagesCat. No.: HY-130463RCAS No.: 268550-95-4Synonyms: PG(16:0/18:1) sodium (Standard); 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) sodium (Standard)POPG (Standard) (PG(16:0/18:1) (Standard)) sodium is the analytical standard of POPG (sodium) (HY-130463). This product is intended for research and analytical applications. POPG (sodium) is a negatively charged phospholipid. POPG (sodium) affects the interactions of membrane proteins with other molecules by changing the charge characteristics of the lipid environment. POPG (sodium) increases the apparent affinity of Gαq and Gβ1γ1 for activated NTS1. POPG (sodium) can interact with the positive charge of peptides. POPG sodium salt can be used in Parkinson's disease research.
-
Calcium propionate, meets analytical specification of E282 (Standard)
0 ImagesCat. No.: HY-B1580ARCAS No.: 4075-81-4Synonyms: Bioban-C, meets analytical specification of E282 (Standard)Calcium propionate, meets analytical specification of E282 (Standard) (Bioban-C, meets analytical specification of E282 (Standard)) is the analytical standard of Calcium propionate, meets analytical specification of E282 (HY-B1580A). This product is intended for research and analytical applications. Calcium propionate, meets analytical specification of E282 is a calcium salt of Propionic acid with oral activity, which can be hydrolyzed into propionate and calcium ions. Calcium propionate, meets analytical specification of E282 elevates intracellular ROS levels in tumor cells, depletes GSH, reduces mitochondrial membrane potential, and thereby induces tumor cell apoptosis. In mouse colitis models, Calcium propionate, meets analytical specification of E282 modulates inflammatory factors such as IFN-γ, calprotectin, and Pglyrp3, ameliorating intestinal inflammation and metabolic disorders. In ruminants, Calcium propionate, meets analytical specification of E282 serves as a gluconeogenic precursor, regulating rumen fermentation and microbial diversity; in high-fat diet rats, it alters gut microbiota composition and affects blood biochemical parameters. Calcium propionate, meets analytical specification of E282 is commonly used as a food and feed additive, and is also used in research related to hypocalcemia, dyslipidemia, colitis, and lung cancer.
-
7-Aminocephalosporanic acid (Standard)
0 Images7-Aminocephalosporanic acid (Standard) is the analytical standard of 7-Aminocephalosporanic acid. This product is intended for research and analytical applications. 7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor.
-
A-784168 (Standard)
0 ImagesCat. No.: HY-108460RCAS No.: 824982-41-4A-784168 (Standard) is the analytical standard of A-784168 (HY-108460). This product is intended for research and analytical applications. A-784168 is a potent and orally active inhibitor of vanilloid receptor type 1 (TRPV1). Vanilloid receptor type 1 (TRPV1) is a ligand-gated nonselective cation channel that is considered to be an important integrator of various pain stimuli such as endogenous lipids, capsaicin, heat, and low pH. A-784168 has good CNS penetration.
-
Saracatinib difumarate (Standard)
0 ImagesSynonyms: AZD0530 difumarate (Standard)Saracatinib (difumarate) (Standard) is the analytical standard of Saracatinib (difumarate). This product is intended for research and analytical applications. Saracatinib (AZD0530) difumarate is a potent Src inhibitor with IC50 values of 2.7-11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr and Blk, and is selective for other tyrosine kinases. .
-
DMBA (Standard)
0 ImagesSynonyms: 7,12-DMBA (Standard); 7,12-Dimethylbenzanthracene (Standard)DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH). DMBA is used to induce tumor formation in various rodent models.
-
ZINC69391 (Standard)
0 ImagesCat. No.: HY-102078RCAS No.: 303094-67-9ZINC69391 (Standard) is the analytical standard of ZINC69391 (HY-102078). This product is intended for research and analytical applications. ZINC69391, a specific Rac1 inhibitor, interferes with Rac1-GEF interaction by masking Trp56 residue on Rac1 surface. ZINC69391 interferes with the interaction of Rac1 with Dock180 and reduces Rac1-GTP levels. ZINC69391 induces apoptosis, and shows antiproliferative and antimetastatic effects.
-
11-Oxomogroside IIIE (Standard)
0 ImagesCat. No.: HY-N6920RCAS No.: 2096516-68-411-Oxomogroside IIIE (Standard) is the analytical standard of 11-Oxomogroside IIIE. This product is intended for research and analytical applications. 11-Oxomogroside IIIE is a cucurbitane triterpene glycoside isolated from Lo Han Kuo (Siraitia grosvenori).
-
Tetrahydro-2H-pyran-2-one (Standard)
0 ImagesCat. No.: HY-W012997RCAS No.: 542-28-9Synonyms: δ-valerolactone (Standard)Tetrahydro-2H-pyran-2-one (δ-valerolactone) is an endogenous metabolite with antioxidant capacity. Tetrahydro-2H-pyran-2-one is the small active molecule and can be used as drug intermediate.
-
N,N-Diethyl-p-phenylenediamine Sulfate (Standard)
0 ImagesCat. No.: HY-W009425RCAS No.: 6283-63-2N,N-Diethyl-p-phenylenediamine Sulfate (Standard) is the analytical standard of N,N-Diethyl-p-phenylenediamine Sulfate. This product is intended for research and analytical applications. N,N-Diethyl-p-phenylenediamine Sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
-
N-Acetyl-L-arginine (Standard)
0 ImagesSynonyms: Ac-Arg-OH (Standard)N-Acetyl-L-arginine (Ac-Arg-OH) is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic) pediatric population. N-Acetyl-L-arginine shows synergistic activity with glycine buffer. N-Acetyl-L-arginine suppresses the aggregation of intravenous immunoglobulins with a minimum decrease in transition temperature. N-Acetyl-L-arginine dramatically reduces IL-1 expression in the presence of silicone oil. N-Acetyl-L-arginine also demonstrates colloidal stability.
-
Disopyramide phosphate (Standard)
0 ImagesCat. No.: HY-12533ARCAS No.: 22059-60-5Synonyms: Dicorantil phosphate (Standard); SC-7031 phosphate (Standard)Disopyramide (phosphate) (Standard) is the analytical standard of Disopyramide (phosphate). This product is intended for research and analytical applications. Disopyramide phosphate is a class IA antiarrhythmic agent with efficacy in ventricular and atrial arrhythmias. Disopyramide phosphate blocks the fast inward sodium current of cardiac muscle and prolongs the duration of cardiac action potentials. Disopyramide phosphate inhibits HERG encoded potassium channels. Disopyramide phosphate also exhibits complex protein binding, and has a potent negative inotropic action.
-
Meticrane (Standard)
0 ImagesMeticrane (Standard) is the analytical standard of Meticrane. This product is intended for research and analytical applications. Meticrane is a diuretic. Meticrane inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule. Meticrane is used to treat essential hypertension.
-
9-Phenanthrol (Standard)
0 ImagesSynonyms: 9-Hydroxyphenanthrene (Standard); NSC 50554 (Standard)9-Phenanthrol (Standard) is the analytical standard of 9-Phenanthrol. This product is intended for research and analytical applications. 9-Phenanthrol (9-Hydroxyphenanthrene) is a selective TRPM4 inhibitor with an IC50 of 17 μM. 9-Phenanthrol has no inhibitory activity on TRPM5, TRPC6, and CFTR. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury.
-
R-1479 (Standard)
0 ImagesSynonyms: 4'-Azidocytidine (Standard)R-1479 (Standard) is the analytical standard of R-1479 (HY-10444). This product is intended for research and analytical applications. R-1479 (4'-Azidocytidine), a nucleoside analogue, is a specific inhibitor of RNA-dependent RNA polymerase (RdRp) of HCV. R-1479 inhibits HCV replication in the HCV subgenomic replicon system (IC50=1.28 μM). R-1479 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
-
Ertabresib (Standard)
0 ImagesCat. No.: HY-111485RCAS No.: 1820889-23-3Synonyms: INCB-057643 (Standard)Ertabresib (Standard) (INCB-057643 (Standard)) is the analytical standard of Ertabresib (HY-111485). This product is intended for research and analytical applications. Ertabresib (INCB-057643) is an orally active BET protein inhibitor. Ertabresib blocks gene transcription by targeting the BET protein family, induces cell cycle arrest and apoptosis by downregulating proto-oncogenes such as c-MYC, and additionally reduces the expression of FOXP3 and PD-L1 to improve the immune microenvironment. It also exerts synergistic effects and overcomes drug resistance when combined with chemotherapy and XPO1 inhibitors. Ertabresib can be used in research related to high-grade B-cell lymphoma with MYC and BCL2 rearrangements, pancreatic cancer, pancreatitis, and metastatic castration-resistant prostate cancer.
-
JFD00244 (Standard)
0 ImagesCat. No.: HY-108986RCAS No.: 96969-83-4
