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Drug Isomer

Drug Isomer

Drug isomers are compounds with the same molecular formula but different atomic arrangements or spatial configurations. They are divided into structural isomers and stereoisomers, and have different biological activities, safety and metabolic characteristics. Drug isomers can be used as drug improvement groups or drug efficacy control groups. For example, Carvedilol has higher bioavailability and better safety than (R)-Carvedilol.

Drug Isomer Related Products (434):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-148336
    (E)-IDO1/TDO-IN-5
    (E)-IDO1/TDO-IN-5 is the E configuration of IDO1/TDO-IN-5 (HY-148336A). IDO1/TDO-IN-5 is a dual IDO1/TDO inhibitor with IC50 values of 0.018 and 0.025 μM, respectively.
    (E)-IDO1/TDO-IN-5
  • HY-W012732R
    Isoquinoline (Standard)
    Isoquinoline (Standard) is the analytical standard of Isoquinoline. This product is intended for research and analytical applications. Isoquinoline is an analog of pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities.
    Isoquinoline (Standard)
  • HY-167917
    Conjugated linoleic acid
    Conjugated linoleic acid is a group of isomers of Linoleic acid (HY-N0729) containing conjugated double bonds. Conjugated linoleic acid is mainly derived from dairy products and ruminant meats. Conjugated linoleic acid exhibits various activities such as anti-carcinogenicity, immunomodulation, weight loss promotion, reduction of muscle damage, and alleviation of inflammatory responses. Conjugated linoleic acid can be used as a food additive.
    Conjugated linoleic acid
  • HY-184153
    IMP-2958
    IMP-2958 is an inactive enantiomeric negative control probe with significantly reduced binding to RAB27A/B-Cys123.IMP-2958 serves as a negative control probe for off-target binding in phenotypic assays related to RAB27A/B studies.IMP-2958 functions as a control for stereoselective targeted covalent inhibitors of the RAB27-effector protein-protein interaction.
    IMP-2958
  • HY-145572B
    (S)-Imlunestrant tosylate
    		Control 98.74%
    (S)-Imlunestrant ((S)-LY-3484356) tosylate is an (S)-enantiomer of Imlunestrant (HY-145572). (S)-Imlunestrant tosylate can be used in research of cancer.
    (S)-Imlunestrant tosylate
  • HY-15584C
    (R)-Taltobulin
    (R)-Taltobulin ((R)-HTI-286) can be used as a reference substance.
    (R)-Taltobulin
  • HY-N15682
    13-cis-β-Carotene
    		Chemical
    13-cis-β-Carotene ((7Z)-Provitamin A; (7Z)-beta-Carotene) is a provitamin A carotenoid isomer found in leaves, flowers, stems, and fruit of Momordica charantia. 13-cis-β-Carotene undergoes nonenzymatic isomerization to other β-carotene isomers during aerobic incubation, extraction, and analysis. 13-cis-β-Carotene can be used for the research of chronic diseases.
    13-cis-β-Carotene
  • HY-186169A
    S-MDDMA
    S-MDDMA is the S-enantiomer of (R,S)-MDDMA (HY-186169B), and mediates serotonin release from cells expressing SERT.
    S-MDDMA
  • HY-155295
    Z-CITCO
    Z-CITCO is the cis isomer of CITCO (HY-103244). Z-CITCO is an agonist of constitutive androstane receptor (CAR) with an EC50 value of 3.9 µM.
    Z-CITCO
  • HY-W698445
    α-Nicotine
    α-Nicotine is the α-isomer of Nicotine. Nicotine is a nicotinic acetylcholine receptor (nAChR) agonist. Nicotine is promising for research of neuropsychiatric disorders (e.g., schizophrenia, ADHD).
    α-Nicotine
  • HY-16560B
    (R)-Camptothecin
    (R)-Camptothecin is an enantiomer of Camptothecin (CPT), is inactive as an inhibitor of the DNA religation reaction and consequently do not poison Top1.
    (R)-Camptothecin
  • HY-Z15805
    Teprenone Impurity 5
    Teprenone Impurity 5 (5Z-GGA) is the cis-isomer of Teprenone (HY-B0779). Teprenone Impurity 5 has inhibitory activity on the proliferation of human ovarian cancer cells Caov-3, and can block the invasion process of cancer cells. Teprenone Impurity 5 can induce the expression of heat shock protein 70 (HSP70) and thioredoxin (Trx). Teprenone Impurity 5 can be used for the research of ovarian cancer.
    Teprenone Impurity 5
  • HY-120337B
    cis-V-11-0711
    cis-V-11-0711 is the cis form of V-11-0711 (HY-120337). V-11-0711 is a potent and selective Chk-α (IC50 = 20 nM) inhibitor. V-11-0711 can significantly reduce PCho levels. V-11-0711 causes a reversible growth arrest. V-11-0711 induces apoptosis at high concentrations. V-11-0711 can be used for the study of cervical cancer and triple-negative breast cancer.
    cis-V-11-0711
  • HY-165624B
    (R)-LY-41
    (R)-LY-41, R-enantiomer of LY-41 (HY-165624), is 2-Sminotetralin (HY-W022362) derivative and 8-OH-DPAT (HY-112061) analogue. (R)-LY-41 is a potent and selective 5-HT1A receptor agonist. (R)-LY-41 can reduce the accumulation of 5-hydroxytryptophan (the precursor for 5-HT synthesis) in the rat brain induced by decarboxylase inhibitors (NSD 1015). (R)-LY-41 can lower the body temperature of rats and inhibit the escape response from the cage. (R)-LY-41 can induce the 5-HT behavioral syndrome but is weaker than (S)-LY-41 (HY-165624A). (R)-LY-41 can be used for the research of neurological disease, such as depression and anxiety.
    (R)-LY-41
  • HY-135406
    (3R,5R)-Rosuvastatin Lactone
    (3R,5R)-Rosuvastatin Lactone is an isomer of Rosuvastatin Lactone.
    (3R,5R)-Rosuvastatin Lactone
  • HY-131450A
    (E)-1α,25-Dihydroxyprevitamin D3
    (E)-1α,25-Dihydroxyprevitamin D3 is a structurally related analog of 1α,25(OH)2D3.
    (E)-1α,25-Dihydroxyprevitamin D3
  • HY-W714853
    (+)-Theta-cypermethrin
    (+)-Theta-cypermethrin is a stereoisomer of Cypermethrin (HY-B0829) that possesses blood-brain barrier penetration ability and binds to AKT1, SRC, STAT3 and EGFR with high affinity. (+)-Theta-cypermethrin reduces the amplitude of delayed rectifier potassium channel currents, shifts the steady-state activation curve to negative potentials, and shifts the steady-state inactivation curve to negative potentials at higher concentrations. (+)-Theta-cypermethrin induces abnormal electrical activity in rat hippocampal neurons. (+)-Theta-cypermethrin causes chronic respiratory system damage and exhibits neurotoxicity.
    (+)-Theta-cypermethrin
  • HY-N15915
    ent-25-Hydroxycholesterol
    ent-25-Hydroxycholesterol is an enantiomer of 25-Hydroxycholesterol (HY-113134).
    ent-25-Hydroxycholesterol
  • HY-15150C
    (R)-Bemcentinib
    (R)-Bemcentinib ((R)-R428) is the R-isomer of Bemcentinib (HY-15150). Bemcentinib (R428) is a selective, orally active Axl inhibitor with an IC50 of 14 nM. Bemcentinib blocks tumor metastasis and prolongs survival in metastatic breast cancer models.
    (R)-Bemcentinib
  • HY-186170A
    S-MDMA
    S-MDMA is an isomer of 4-methylenedioxymethamphetamine (MDMA) isomer. S-MDMA can promotes cortical neurons growth.
    S-MDMA