Free Radical Scavengers
Free radical scavengers are bioactive substances that eliminate reactive free radicals. Free radicals with unpaired electrons easily damage lipids, proteins and DNA, causing oxidative stress and cell aging.
Free radical scavengers neutralize radicals by donating electrons or hydrogen atoms to form stable inert compounds. Their scavenging capacity is measured by in vitro assays including DPPH and ABTS tests.
Common natural scavengers are polyphenols, flavonoids, vitamin C and vitamin E. They are widely studied for food preservation, cosmetic anti-oxidation and treatments for oxidative damage-related diseases.
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Free Radical Scavengers Related Products (379)
Related Products (379)
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EGFR/BRAFV600E-IN-2
0 ImagesCat. No.: HY-149517EGFR/BRAFV600E-IN-2 (compound 3g) is a potential multi-target inhibitor of EGFR, BRAFV600E, and EGFRT790M, and an inducer of apoptosis. EGFR/BRAFV600E-IN-2 can activate caspase-3, 8, and Bax, and downregulate the anti-apoptotic protein Bcl2, inducing apoptosis. EGFR/BRAF V600E-IN-2 also has antioxidant activity and DPPH free radical scavenging potency.
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7-Demethylnaphterpin
0 ImagesCat. No.: HY-N14765CAS No.: 137109-43-4Synonyms: Naphthgeranine A7-Demethylnaphterpin (Naphthgeranine A) is a free radical scavenger that can be isolated from Streptomyces prunicolor.
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1,2',6'-Triacetyl-3,6-diferuloylsucrose
0 ImagesCat. No.: HY-N21602CAS No.: 188433-99-01,2',6'-Triacetyl-3,6-diferuloylsucrose is a sucrose phenylpropanoid ester and also a phenolic component. 1,2',6'-Triacetyl-3,6-diferuloylsucrose is isolated from the whole plant of Polygonum perfoliatum and the peel of Eleocharis tuberosa. 1,2',6'-Triacetyl-3,6-diferuloylsucrose exerts its effects by scavenging DPPH free radicals. 1,2',6'-Triacetyl-3,6-diferuloylsucrose exerts its effects via reducing power.
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Antioxidant agent-13
0 ImagesCat. No.: HY-155123CAS No.: 2966778-87-8Antioxidant agent-13 (Compound 5f) is an antioxidant agent. Antioxidant agent-13 inhibits DPPH and FRAP with IC50s of 80.33 and 85.69 μM. Antioxidant agent-13 also inhibits LOX and XO enzymes with IC50s of 16.85 and 23.01 μM.
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AChE-IN-111
0 ImagesCat. No.: HY-182332AChE-IN-111 is an acetylcholinesterase inhibitor with a IC50 of 0.37 μM. AChE-IN-111 scavenges various reactive oxygen and nitrogen species. AChE-IN-111 exhibits significant antioxidant potential and iron regulatory protein levels. AChE-IN-111 can be used for the research of Alzheimer's disease.
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MK-447
0 ImagesCat. No.: HY-100297CAS No.: 58456-91-0MK-447 is a free radical scavenger, also a nonsteroidal antiinflammatory agent, and enhances the formation of the endoperoxide, PGH2, and other prostaglandins.
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VH9
0 ImagesCat. No.: HY-P11916VH9 is a Free radical scavenger. VH9 binds to the active pocket of Keap1, blocks the interaction between Keap1 and Nrf2, and activates the Keap1-Nrf2 antioxidant pathway. VH9 inhibits ROS production. VH9 scavenges ABTS and DPPH free radicals through hydrogen bonding and hydrophobic interactions. VH9 protects cells from oxidative stress damage.
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U-78517 dihydrochloride
0 ImagesCat. No.: HY-164295ACAS No.: 133681-84-2U-78517 dihydrochloride, a Trolox (HY-101445) analog, is a potent antioxidant. U-78517 dihydrochloride inhibits DCVC (HY-19717)-induced lipid peroxidation, scavenges DPPH, oxygen- and nitrogen-based free radicals. U-78517 dihydrochloride attenuates hypoxic injury in iaolated cardiac myocytes. U-78517 dihydrochloride can be used for the research of hypoxic injury, cerebral ischemia, and cardiovascular disease.
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BChE/MAO-B-IN-2
0 ImagesCat. No.: HY-175524BChE/MAO-B-IN-2 is a dual inhibitor of BChE (IC50 = 0.05 μM, Ki = 0.01 μM) and MAO-B (IC50 = 0.45 μM, Ki = 0.08 μM) with good blood-brain barrier permeability. BChE/MAO-B-IN-2 exhibits antioxidant activity, including DPPH radical scavenging, CUPRAC copper ion reduction, and superoxide anion scavenging. BChE/MAO-B-IN-2 can be used for the study of Alzheimer's disease (AD).
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AChE-IN-116
0 ImagesCat. No.: HY-183303AChE-IN-116 is a selective acetylcholinesterase (AChE) inhibitor with an electric eel AChE IC50 of 1.60 μM and Ki of 1.72 μM. AChE-IN-116 exhibits weak ability to scavenge DPPH radical. AChE-IN-116 can be used for the research of Alzheimer's disease.
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2,5-Dimethylchromone-7-O-β-D-glucopyranoside
0 ImagesCat. No.: HY-N15727CAS No.: 1251459-63-82,5-Dimethylchromone-7-O-β-D-glucopyranoside is an orally active chromone glycoside found in the underground parts of Rheum australe. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside shows a DPPH radical scavenging activity with an IC50 value of 66.9 μM. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside scavenges free radicals by providing hydrogen atoms through phenolic hydroxyl groups, inhibiting lipid peroxidation. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside is promising for research of oxidative stress-related diseases such as inflammation and skin diseases.
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Salvianolic acid L
0 ImagesCat. No.: HY-W717882CAS No.: 389065-74-1Synonyms: (-)-Salvianolic acid LSalvianolic acid L ((-)-Salvianolic acid L) is a natural rosmarinic acid dimer and phenolic antioxidant found in Salvia officinalis. Salvianolic acid L effectively scavenges DPPH and superoxide anion radicals. Salvianolic acid L is applicable to oxidative stress and antioxidant research.
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1,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran
0 ImagesCat. No.: HY-N9283CAS No.: 146905-24-01,2-Diacetoxy-4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzofuran, isolated from the edible mushroom Sarcodon leucopus, has antioxidant effects in the DPPH scavenging assay with the IC50 of 28 μM, inhibits malondialdehyde (MDA) with the IC50 of 71 μM, and inhibits α-glucosidase with the IC50 of 6.22 μM.
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Methyl (Z)-ferulate
0 ImagesCat. No.: HY-N16424CAS No.: 34298-89-0Synonyms: Me cis-ferulate; cis-Ferulic acid methyl esterMethyl (Z)-ferulate (Me cis-ferulate) (cis-Ferulic acid methyl ester) is an endogenous Germination self-inhibitor. Methyl (Z)-ferulate can be isolated from the leaves of Tetragonia tetragonoides. Methyl (Z)-ferulate blocks uredospores germination in rust fungi by reversibly inhibiting the digestion of the germination pore plug through the regulation of pre-existing enzyme activity. Methyl (Z)-ferulate also has antioxidant activity, effectively scavenging DPPH and ABTS+ radical.
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Mammea E/BA
0 ImagesCat. No.: HY-N19852CAS No.: 111321-13-2Mammea E/BA is a prenylated coumarin anticancer agent that can be isolated from the seeds of Mammea americana. Mammea E/BA scavenges DPPH free radicals. Mammea E/BA induces cytotoxicity in colon cancer cells. Mammea E/BA can be used for the research of colon cancer.
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Anticancer agent-365
0 ImagesCat. No.: HY-189298Anticancer agent-365 is a pyrimidine-benzothiazole hybrid derivative that exhibits selective antiproliferative activity against A549 and MCF-7 tumor cells. Anticancer agent-365 is predicted to bind within the ATP-binding pocket of the VEGFR-2 kinase domain. Anticancer agent-365 possesses DNA intercalating binding ability, DNA oxidative damage protective activity, and antioxidant free radical scavenging activity. Anticancer agent-365 can be used for research on lung cancer and breast cancer.
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Antioxidant agent-3
0 ImagesCat. No.: HY-146172CAS No.: 2710376-48-8Antioxidant agent-3 (Compound 14q), an potent antioxidant, displays potent DPPH radicals scavenging activity and ABTS+ scavenging activity with IC50s of 26.58 and 30.31 μM, respectively. Antioxidant agent-3 (Compound 14q) increases reactive oxygen species (ROS), superoxide dismutase (SOD) and glutathione (GSH), and reduced lactate dehydrogenase (LDH) in H2O2-treated HepG2 cells.
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Neuroprotective agent 6
0 ImagesCat. No.: HY-168501Neuroprotective Agent 6 (Compound Y12) is a neuroprotective agent with antioxidant activity and capabilities in DPPH, ABTS radical scavenging. Neuroprotective Agent 6 demonstrates superior neuroprotective effects in both cellular models induced by oxygen-glucose deprivation/reoxygenation (OGD/R) and animal models induced by transient middle cerebral artery occlusion (tMCAO). Additionally, Neuroprotective Agent 6 exhibits significant metal chelating activity towards Cu2+.
