1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Alafosfalin

Alafosfalin 

Cat. No.: HY-119881
Handling Instructions

Alafosfalin is an inhibitor of cell wall biosynthesis. Alafosfalin is a phosphonodipeptide with antibacterial properties.

For research use only. We do not sell to patients.

Alafosfalin Chemical Structure

Alafosfalin Chemical Structure

CAS No. : 60668-24-8

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Alafosfalin is an inhibitor of cell wall biosynthesis. Alafosfalin is a phosphonodipeptide with antibacterial properties[1].

IC50 & Target

Antibacterial[1]

In Vitro

Alafosfalin is highly active against Escherichia coli and moderately active against Serratia, Klebsiella, Enterobacter, and Citrobacter, but less active against gram-positive organisms than were beta-lactams such as cephazolin or ampicillin and inactive against indole-positive Proteus, Pseudomonas, and Acinetobacter[1].

In Vivo

After s.c. administration to rats, Alafosfalin is rapidly absorbed with half-lives (t1/2) of approximately 20 minutes[2].

Animal Model: Pairs of male SpragueDawley rats (250 to 350 g)[2]
Dosage: 20, 100, and 500 mg/ kg (single doses) or 800 mg/kg per day for 14 days (Pharmacokinetic Analysis)
Administration: Administrated by s.c.
Result: Rapidly absorbed; peak concentrations were found within 20 minutes of dosing with half-lives of approximately 20 minutes.
Molecular Weight

196.14

Formula

C₅H₁₃N₂O₄P

CAS No.

60668-24-8

SMILES

OP(O)([[email protected]@H](NC([[email protected]@H](N)C)=O)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

AlafosfalinBacterialAntibioticcellwallphosphonodipeptideantibacterialEscherichia coliInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Alafosfalin
Cat. No.:
HY-119881
Quantity:
MCE Japan Authorized Agent: