(+)-Alprenolol
(+)-Alprenolol ((R)-Alprenolol; D-Alprenolol) is a 5-HT1A receptor antagonist with a Ki value of 5400 nM. (+)-Alprenolol also acts as a non-selective β-receptor (β-receptor) blocker. (+)-Alprenolol can be used in the research of cardiovascular and cerebrovascular diseases.
For research use only. We do not sell to patients.
- CAS No.: 23846-72-2
- Formula: C15H23NO2
- Molecular Weight:249.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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5-HT1A Receptor 5400 nM (Ki) |
β-adrenoceptor |
(+)-Alprenolol ((R)-5) binds to the human 5-HT1A Asn386Val mutant receptor with a Ki of 56000 nM, showing 10-fold lower affinity than for the wild-type receptor and reduced stereoselectivity relative to its S enantiomer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 23846-72-2
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Molecular Weight 249.35
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Formula C15H23NO2
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SMILES
O(C[C@@H](CNC(C)C)O)C1=C(CC=C)C=CC=C1
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Synonyms
(R)-Alprenolol; D-Alprenolol
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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