(+)-Alprenolol
(+)-Alprenolol ((R)-Alprenolol; D-Alprenolol) is a 5-HT1A receptor antagonist with a Ki value of 5400 nM. (+)-Alprenolol also acts as a non-selective β-receptor (β-receptor) blocker. (+)-Alprenolol can be used in the research of cardiovascular and cerebrovascular diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 23846-72-2
- 分子式: C15H23NO2
- 分子量:249.35
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
5-HT1A Receptor 5400 nM (Ki) |
β-adrenoceptor |
体外実験
(+)-Alprenolol ((R)-5) binds to the human 5-HT1A Asn386Val mutant receptor with a Ki of 56000 nM, showing 10-fold lower affinity than for the wild-type receptor and reduced stereoselectivity relative to its S enantiomer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 23846-72-2
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分子量 249.35
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分子式 C15H23NO2
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SMILES
O(C[C@@H](CNC(C)C)O)C1=C(CC=C)C=CC=C1
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別名
(R)-Alprenolol; D-Alprenolol
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
(+)-Alprenolol 関連分類
HY-165357 関連分類
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