AMD 3329 octahydrobromide
AMD 3329 octahydrobromide is a potent and selective anti-HIV-1 and HIV-2 compound with activity to inhibit viral replication. AMD 3329 blocks viral invasion by binding to the chemokine receptor CXCR4. AMD 3329 exhibits EC50 values as low as 0.8 and 1.6 nM when inhibiting HIV-1 and HIV-2 replication, showing better antiviral efficacy than AMD3100. AMD 3329 significantly inhibits the binding of specific CXCR4 monoclonal antibodies and the Ca(2+) flux induced by SDF-1alpha. AMD 3329 is also able to effectively interfere with virus-induced syncytium formation, with an EC50 value of 12 nM.
For research use only. We do not sell to patients.
- CAS No.: 170861-77-5
- Formula: C34H58Br8N8
- Molecular Weight:1218.11
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 170861-77-5
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Molecular Weight 1218.11
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Formula C34H58Br8N8
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SMILES
C12=CC=CC(CCNCCN(CCNCC2)CC3=CC=C(CN4CCNCCC5=CC=CC(CCNCC4)=N5)C=C3)=N1.Br.[8]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AMD 3329 octahydrobromide Related Classifications
HY-164682 Related Classifications
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