Aldoview
Based on 1 Customer Validation
AldoView (Compound 3) is an intermediate. AldoView can be labeled with fluorine-18 to synthesize [18F]AldoView. [18F]AldoView is a highly selective aldosterone synthase PET imaging agent. AldoView can be used in imaging studies of primary aldosteronism.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.05%
- CAS. Nr.: 1356479-94-1
- Formel: C15H10F3N3
- Molecular Weight:289.26
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Speicherung:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
IC50 & Target
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Aldosterone Synthase |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| COS-7 | IC50 |
10000 nM
Compound: 26
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Inhibition of human CYP17 expressed in COS7 cells incubated for 1 hr before 17-hydroxypregnenolone substrate addition by EIA method
Inhibition of human CYP17 expressed in COS7 cells incubated for 1 hr before 17-hydroxypregnenolone substrate addition by EIA method
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[PMID: 26005536] |
Chemical Information
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CAS. Nr. 1356479-94-1
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Appearance Solid
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Molecular Weight 289.26
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Formel C15H10F3N3
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Color White to off-white
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SMILES
FC1=CC(C2=NC3=C(N2C4CC4)C=C(F)C(F)=C3)=CN=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 12.5 mg/mL (43.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4571 mL | 17.2855 mL | 34.5710 mL | 86.4274 mL |
| 5 mM | 0.6914 mL | 3.4571 mL | 6.9142 mL | 17.2855 mL | |
| 10 mM | 0.3457 mL | 1.7285 mL | 3.4571 mL | 8.6427 mL | |
| 15 mM | 0.2305 mL | 1.1524 mL | 2.3047 mL | 5.7618 mL | |
| 20 mM | 0.1729 mL | 0.8643 mL | 1.7285 mL | 4.3214 mL | |
| 25 mM | 0.1383 mL | 0.6914 mL | 1.3828 mL | 3.4571 mL | |
| 30 mM | 0.1152 mL | 0.5762 mL | 1.1524 mL | 2.8809 mL | |
| 40 mM | 0.0864 mL | 0.4321 mL | 0.8643 mL | 2.1607 mL |
Aldoview Related Classifications
HY-180533 Related Classifications
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