BOP sodium
Based on 1 Customer Validation
BOP sodium is a potent and selective dual α9β1/α4β1 integrin inhibitor with Kd values in the picomolar range. BOP sodium shows the rapid and preferential mobilization of hematopoietic stem cell (HSC) and progenitors. BOP sodium has little inhibitory activity on α4β7, α1β1, α2β1, and α5β1, αIIBβ3 integrins.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.25%
- CAS. Nr.: 1947348-42-6
- Formel: C25H28N3NaO7S
- Molecular Weight:537.56
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Speicherung:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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α4β1 |
α9β1 |
Chemical Information
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CAS. Nr. 1947348-42-6
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Appearance Solid
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Molecular Weight 537.56
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Formel C25H28N3NaO7S
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Color White to off-white
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SMILES
O=C(O[Na])[C@H](CC1=CC=C(OC(N2CCCC2)=O)C=C1)NC([C@H]3N(S(=O)(C4=CC=CC=C4)=O)CCC3)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Lösungsmittel & Löslichkeit
H2O : 125 mg/mL (232.53 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. R Blake Pepinsky, et al. Comparative assessment of the ligand and metal ion binding properties of integrins alpha9beta1 and alpha4beta1. Biochemistry. 2002 Jun 4;41(22):7125-41. [Content Brief]
[2]. Benjamin Cao, et al. Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist. Nat Commun. 2016 Mar 15;7:11007. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.8603 mL | 9.3013 mL | 18.6026 mL | 46.5064 mL |
| 5 mM | 0.3721 mL | 1.8603 mL | 3.7205 mL | 9.3013 mL | |
| 10 mM | 0.1860 mL | 0.9301 mL | 1.8603 mL | 4.6506 mL | |
| 15 mM | 0.1240 mL | 0.6201 mL | 1.2402 mL | 3.1004 mL | |
| 20 mM | 0.0930 mL | 0.4651 mL | 0.9301 mL | 2.3253 mL | |
| 25 mM | 0.0744 mL | 0.3721 mL | 0.7441 mL | 1.8603 mL | |
| 30 mM | 0.0620 mL | 0.3100 mL | 0.6201 mL | 1.5502 mL | |
| 40 mM | 0.0465 mL | 0.2325 mL | 0.4651 mL | 1.1627 mL | |
| 50 mM | 0.0372 mL | 0.1860 mL | 0.3721 mL | 0.9301 mL | |
| 60 mM | 0.0310 mL | 0.1550 mL | 0.3100 mL | 0.7751 mL | |
| 80 mM | 0.0233 mL | 0.1163 mL | 0.2325 mL | 0.5813 mL | |
| 100 mM | 0.0186 mL | 0.0930 mL | 0.1860 mL | 0.4651 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
BOP sodium Related Classifications
HY-129453 Related Classifications
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