ML165
ML165 (RUC-2) is an aIIbb3 receptor antagonist. ML165 has orthosteric inhibition effect at the RGD binding domain. ML165 inhibits platelet adhesion to fibrinogen, and inhibits platelet aggregation (IC50: 96 nM).
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- CAS. Nr.: 1355454-05-5
- Formel: C17H19N7O2S
- Molecular Weight:385.44
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Platelet | IC50 |
0.096 μM
Compound: 2, RUC-2, ML165
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Antiplatelet activity in platelet (unknown origin) assessed as inhibition of platelet aggregation
Antiplatelet activity in platelet (unknown origin) assessed as inhibition of platelet aggregation
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[PMID: 24461295] |
Chemical Information
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CAS. Nr. 1355454-05-5
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Molecular Weight 385.44
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Formel C17H19N7O2S
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SMILES
O=C(NC1=CC=CC(C(S2)=NN(C2=NC(N3CCNCC3)=C4)C4=O)=C1)CN
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Synonyms
RUC-2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
ML165 Related Classifications
HY-120694 Related Classifications
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