CDK
Cyclin-dependent kinases supply the cell-cycle engine of the CMGC group. Twenty human genes, CDK1 through CDK20, split into two functional tiers: CDK1, CDK2, CDK4 and CDK6 partner with A-, B-, D- and E-type cyclins to drive mitotic and G1/S transitions and to phosphorylate retinoblastoma protein, whereas CDK7, CDK8, CDK9, CDK12 and CDK13 phosphorylate the RNA polymerase II C-terminal domain to control transcription and mRNA processing. CDK5 is neuronal and activated by p35 or p39 instead of cyclins, while the PCTAIRE kinases CDK16-CDK18 and CDK20 remain poorly defined. Activation requires cyclin binding plus CAK-mediated T-loop phosphorylation. CDK4/6 inhibitors such as palbociclib validate the family therapeutically.
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CDK Recombinant Proteins (84)
CDK1-CCNE1 Heterodimer Protein, Human (Inactive, sf9, His-GST)
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Art. -Nr.: HY-P74257
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK1; Cell Division Protein Kinase 1; Prev. CDC2; P34 Protein Kinase; CDC28A; P34CDC2; Cell Division Cycle 2, G1 To S And G2 To M; Cell Cycle Controller CDC2; Cell Division Control Protein 2 Homolog; CDKN1; Cyclin Dependent Kinase 1; Cyclin-Dependent Kinase 1; CCNE1; Cyclin E Variant Ex7del; Prev. CCNE; Cyclin Et; G1/S-Specific Cyclin-E1; PCCNE1; Cyclin E Variant Ex5del; Cyclin E1; Cyclin Es
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CDK2 Protein, Human
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Art. -Nr.: HY-P706199
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuCyclin-dependent kinase 2/CDK2, His; Cyclin-Dependent Kinase 2; Cell Division Protein Kinase 2; p33 Protein Kinase; CDK2; CDKN2
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CDK1 Protein, Human (Active, sf9)
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Art. -Nr.: HY-P702779
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK1; Cell Division Protein Kinase 1; Prev. CDC2; P34 Protein Kinase; CDC28A; P34CDC2; Cell Division Cycle 2, G1 To S And G2 To M; Cell Cycle Controller CDC2; Cell Division Control Protein 2 Homolog; CDKN1; Cyclin Dependent Kinase 1; Cyclin-Dependent Kina
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CDK1 Protein, Human (Inactive, sf9, GST)
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Art. -Nr.: HY-P75668
Reinheit: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CDK1; Cell Division Protein Kinase 1; Prev. CDC2; P34 Protein Kinase; CDC28A; P34CDC2; Cell Division Cycle 2, G1 To S And G2 To M; Cell Cycle Controller CDC2; Cell Division Control Protein 2 Homolog; CDKN1; Cyclin Dependent Kinase 1; Cyclin-Dependent Kina
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CDK9 Protein, Human (sf9, GST)
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Art. -Nr.: HY-P703558
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK9; Tat-Associated Kinase Complex Catalytic Subunit; Prev. CDC2L4; Cyclin-Dependent Kinase 9 (CDC2-Related Kinase); TAK; Serine/Threonine Protein Kinase PITALRE; Cell Division Protein Kinase 9; Serine/Threonine-Protein Kinase PITALRE; Cyclin-Dependent K
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CDK8-CCNC-MED12 Complex Protein, Human (Active, sf9, GST, FLAG, His)
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Art. -Nr.: HY-P701373
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK8; Cell Division Protein Kinase 8; Cyclin Dependent Kinase 8; Mediator Complex Subunit CDK8; Cyclin-Dependent Kinase 8; Protein Kinase K35; K35; CDK8 Protein Kinase; Mediator Of RNA Polymerase II Transcription Subunit CDK8; IDDHBA; CCNC; SRB11 Homolog;
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CDK1-CCNE1 Heterodimer Protein, Human (Active, sf9, GST, His, Flag)
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Art. -Nr.: HY-P702673
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK1; Cell Division Protein Kinase 1; Prev. CDC2; P34 Protein Kinase; CDC28A; P34CDC2; Cell Division Cycle 2, G1 To S And G2 To M; Cell Cycle Controller CDC2; Cell Division Control Protein 2 Homolog; CDKN1; Cyclin Dependent Kinase 1; Cyclin-Dependent Kina
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CDK4-CCND1 Protein, Human (Active, sf9, GST, Flag, His)
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Art. -Nr.: HY-P702682
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK4; Cyclin-Dependent Kinase 4; Cyclin Dependent Kinase 4; Cyclin-Dependent Kinase; PSK-J3; MCPH31; Cell Division Protein Kinase 4; CMM3; CCND1; B-Cell CLL/Lymphoma 1; Prev. PRAD1; PRAD1 Oncogene; Prev. BCL1; Parathyroid Adenomatosis 1; Prev. D11S287E; C
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CDK16-CCNY Protein, Human (Active, sf9, GST, Flag)
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Art. -Nr.: HY-P702696
Reinheit: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CDK16; PCTAIRE-Motif Protein Kinase 1; Prev. PCTK1; FLJ16665; PCTAIRE1; Testis Secretory Sperm-Binding Protein Li 224n; PCTGAIRE; Serine/Threonine-Protein Kinase; PCTAIRE; PCTAIRE Protein Kinase 1; Serine/Threonine-Protein Kinase PCTAIRE-1; Cyclin-Depende
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CDK1-CCNB1 Protein, Human (Active, sf9, GST, Flag, His)
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Art. -Nr.: HY-P702736
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK1; Cell Division Protein Kinase 1; Prev. CDC2; P34 Protein Kinase; CDC28A; P34CDC2; Cell Division Cycle 2, G1 To S And G2 To M; Cell Cycle Controller CDC2; Cell Division Control Protein 2 Homolog; CDKN1; Cyclin Dependent Kinase 1; Cyclin-Dependent Kina
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CDK6-CCND2 Heterodimer Protein, Human (Active, sf9, GST, FLAG, His)
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Art. -Nr.: HY-P701368
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; Cell Division Protein Kinase 6; Cyclin Dependent Kinase 6; Cyclin-Dependent Kinase 6; PLSTIRE; MCPH12; Serine/Threonine-Protein Kinase PLSTIRE; CDKN6; CCND2; G1/S-Specific Cyclin D2; Cyclin D2; KIAK0002; G1/S-Specific Cyclin-D2; MPPH3
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CDK9-CCNT1 Heterodimer Protein, Human (Active, sf9)
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Art. -Nr.: HY-P701376
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK9; Tat-Associated Kinase Complex Catalytic Subunit; Prev. CDC2L4; Cyclin-Dependent Kinase 9 (CDC2-Related Kinase); TAK; Serine/Threonine Protein Kinase PITALRE; Cell Division Protein Kinase 9; Serine/Threonine-Protein Kinase PITALRE; Cyclin-Dependent K
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CDK2-CCND1 Protein, Human (Active, sf9, GST, Flag, His)
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Art. -Nr.: HY-P702676
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; Cyclin Dependent Kinase 2; Cdc2-Related Protein Kinase; Cell Division Protein Kinase 2; Cyclin-Dependent Kinase; Cyclin-Dependent Kinase 2; P33(CDK2); P33 Protein Kinase; CCND1; B-Cell CLL/Lymphoma 1; Prev. PRAD1; PRAD1 Oncogene; Prev. BCL1;
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CDK2-CCNE1 Protein, Human (Active, sf9, GST, His, Flag)
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Art. -Nr.: HY-P702677
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; Cyclin Dependent Kinase 2; Cdc2-Related Protein Kinase; Cell Division Protein Kinase 2; Cyclin-Dependent Kinase; Cyclin-Dependent Kinase 2; P33(CDK2); P33 Protein Kinase; CCNE1; Cyclin E Variant Ex7del; Prev. CCNE; Cyclin Et; G1/S-Specific Cy
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CDK4-CCND2 Protein, Human (Active, sf9, GST, Flag, His)
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Art. -Nr.: HY-P702683
Reinheit: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CDK4; Cyclin-Dependent Kinase 4; Cyclin Dependent Kinase 4; Cyclin-Dependent Kinase; PSK-J3; MCPH31; Cell Division Protein Kinase 4; CMM3; CCND2; G1/S-Specific Cyclin D2; Cyclin D2; KIAK0002; G1/S-Specific Cyclin-D2; MPPH3
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CDK5-p25 Protein, Human (Active, sf9, GST, His, Flag)
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Art. -Nr.: HY-P702685
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK5; Cyclin-Dependent Kinase 5; Cyclin Dependent Kinase 5; TPKII Catalytic Subunit; PSSALRE; Epididymis Secretory Sperm Binding Protein; Serine/Threonine-Protein Kinase PSSALRE; Protein Kinase CDK5 Splicing; Tau Protein Kinase II Catalytic Subunit; CDKN5
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CDK6-CCND1 Heterodimer Protein, Human (Active, sf9, GST, Flag, His)
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Art. -Nr.: HY-P702687
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; Cell Division Protein Kinase 6; Cyclin Dependent Kinase 6; Cyclin-Dependent Kinase 6; PLSTIRE; MCPH12; Serine/Threonine-Protein Kinase PLSTIRE; CDKN6; CCND1; B-Cell CLL/Lymphoma 1; Prev. PRAD1; PRAD1 Oncogene; Prev. BCL1; Parathyroid Adenomatosis 1;
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CDK2-CCNA2 Protein, Human (Active, sf9, GST, His)
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Art. -Nr.: HY-P702675
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; Cyclin Dependent Kinase 2; Cdc2-Related Protein Kinase; Cell Division Protein Kinase 2; Cyclin-Dependent Kinase; Cyclin-Dependent Kinase 2; P33(CDK2); P33 Protein Kinase; CCNA2; Cyclin-A2; Prev. CCN1; Cyclin A; Prev. CCNA; Cyclin A2; Cyclin-A
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CDK2-CCNE1 Protein, Human (Biotinylated, sf9, Avi, Flag)
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Art. -Nr.: HY-P706158
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK2; CDKN2; Cyclin Dependent Kinase 2; Cdc2-Related Protein Kinase; Cell Division Protein Kinase 2; Cyclin-Dependent Kinase; Cyclin-Dependent Kinase 2; P33(CDK2); P33 Protein Kinase; CCNE1; Cyclin E Variant Ex7del; Prev. CCNE; Cyclin Et; G1/S-Specific Cy
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
Capetin (28-54), human
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Synonyms: Serpin B6; Cytoplasmic Antiproteinase; cap; Peptidase Inhibitor
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
