Y02224
Y02224 is a potent BRD4 inhibitor and exhibits reasonable antiproliferative effect on leukemia cells.Y02224 has the potential for? CRPC research.
For research use only. We do not sell to patients.
- CAS No.: 1853988-48-3
- Formula: C20H17BrN2O4S
- Molecular Weight:461.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: BRD4[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
2.99 μM
Compound: 85
|
Antiproliferative activity against human HL60 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human HL60 cells after 72 hrs by CCK8 assay
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[PMID: 26731490] |
| HT-29 | IC50 |
12.9 μM
Compound: 85
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Antiproliferative activity against human HT-29 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human HT-29 cells after 72 hrs by CCK8 assay
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[PMID: 26731490] |
| MV4-11 | IC50 |
1.3 μM
Compound: 85
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Antiproliferative activity against human MV4-11 cells after 72 hrs by CCK8 assay
Antiproliferative activity against human MV4-11 cells after 72 hrs by CCK8 assay
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[PMID: 26731490] |
Chemical Information
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CAS No. 1853988-48-3
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Molecular Weight 461.33
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Formula C20H17BrN2O4S
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SMILES
O=C1C2=C(C3=CC=C2)C(N1CC)=CC=C3NS(C4=C(C=CC(Br)=C4)OC)(=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Y02224 Related Classifications
HY-114902 Related Classifications
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