Flucloxacillin
Based on 1 publication(s) in Google Scholar
Flucloxacillin is an active antibiotic against gram-positive and gram-negative bacteria.
For research use only. We do not sell to patients.
- Purity: 98.02%
- CAS No.: 5250-39-5
- Formula: C19H17ClFN3O5S
- Molecular Weight:453.87
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Flucloxacillin
MoreAll Antibiotic Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
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| Sf21 | IC50 |
208.6 μM
Compound: Flucloxacillin
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Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
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[PMID: 21965623] |
| Sf21 | IC50 |
429.1 μM
Compound: Flucloxacillin
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Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
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[PMID: 21965623] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Wistar rats[1]
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Dosage:200 mg/kg
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Administration:Intraperitoneal injection; three times/day, for 21 days
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Result:Reducted germs in the biofilm and in the bone tissue.
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 5250-39-5
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Appearance Solid
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Molecular Weight 453.87
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Formula C19H17ClFN3O5S
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Color White to off-white
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SMILES
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC(C3=C(C)ON=C3C4=C(F)C=CC=C4Cl)=O)N1C2=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
DMSO : 100 mg/mL (220.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.2033 mL | 11.0164 mL | 22.0327 mL | 55.0819 mL |
| 5 mM | 0.4407 mL | 2.2033 mL | 4.4065 mL | 11.0164 mL | |
| 10 mM | 0.2203 mL | 1.1016 mL | 2.2033 mL | 5.5082 mL | |
| 15 mM | 0.1469 mL | 0.7344 mL | 1.4688 mL | 3.6721 mL | |
| 20 mM | 0.1102 mL | 0.5508 mL | 1.1016 mL | 2.7541 mL | |
| 25 mM | 0.0881 mL | 0.4407 mL | 0.8813 mL | 2.2033 mL | |
| 30 mM | 0.0734 mL | 0.3672 mL | 0.7344 mL | 1.8361 mL | |
| 40 mM | 0.0551 mL | 0.2754 mL | 0.5508 mL | 1.3770 mL | |
| 50 mM | 0.0441 mL | 0.2203 mL | 0.4407 mL | 1.1016 mL | |
| 60 mM | 0.0367 mL | 0.1836 mL | 0.3672 mL | 0.9180 mL | |
| 80 mM | 0.0275 mL | 0.1377 mL | 0.2754 mL | 0.6885 mL | |
| 100 mM | 0.0220 mL | 0.1102 mL | 0.2203 mL | 0.5508 mL |
Flucloxacillin Related Classifications
HY-A0246 Related Classifications
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