1. Metabolic Enzyme/Protease
  2. Cytochrome P450
  3. Azamulin

Azamulin 

Cat. No.: HY-W019847
Handling Instructions

Azamulin is an irreversible, highly selective inhibitior of human CYP3Aa. Azamulin has CYP3A inhibition activity with IC50 values range from 0.03-0.24 μM. Azamulin can be used for the research of metabolism and antiinfection.

For research use only. We do not sell to patients.

Azamulin Chemical Structure

Azamulin Chemical Structure

CAS No. : 76530-44-4

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Azamulin is an irreversible, highly selective inhibitior of human CYP3Aa. Azamulin has CYP3A inhibition activity with IC50 values range from 0.03-0.24 μM. Azamulin can be used for the research of metabolism and antiinfection[1].

IC50 & Target

CYP3A

0.03-0.24 μM (IC50)

In Vitro

Azamulin has CYP3A inhibition activity with IC50 values range from 0.03-0.24 μM[1].
Azamulin has CYP3A inhibition appeared sigmoidal and well behaved with the substrates 7-benzyloxy-4-trifluoromethylcoumarin, testosterone, and midazolam[1].
Azamulin (4.8 μM;10 min) inhibits approximately 95% of testosterone 6beta-hydroxylase activity in the presence of NADPH[1].
Azamulin exhibits good chemical stability when stored in acetonitrile for up to 12 days[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

478.65

Formula

C24H38N4O4S

CAS No.
SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Azamulin
Cat. No.:
HY-W019847
Quantity:
MCE Japan Authorized Agent: