BET-IN-30
BET-IN-30 (Compound 11d) is a BTE family protein inhibitor, which can act as a BRD2/BRD3/BRD4 target protein ligand and be used for the synthesis of PROTACs, such as PROTAC BET Degrader-15 (HY-181729). BET-IN-30 exhibits potent anti-proliferative activity against acute myeloid leukemia (AML) cells such as MV4-11. BET-IN-30 can be used for the study of AML.
For research use only. We do not sell to patients.
- Formula: C25H23ClN4O2
- Molecular Weight:446.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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BRD2 |
BRD3 |
BRD4 |
Chemical Information
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Molecular Weight 446.93
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Formula C25H23ClN4O2
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SMILES
COC1=C(C2=C(C)ON=C2C)C=C3C(C(N([C@@H](C4=CC=CC=C4)C)C(CCl)=N5)=C5C=N3)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)