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Cat. No.: HY-186015

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Arg-TERRα

Arg-TERRα is a mini-PROTAC targeting ERRα. Arg-TERRα induces ERRα degradation via the N-end rule pathway, thereby in inhibiting the proliferation and migration of MCF7 breast cancer cells. Arg-TERRα can be used for breast cancer research.
(Pink: ERRα Target protein ligand; Blue: Ligands for E3 Ligase ligand (HY-N0455); Black: linker).

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CAS No.: 2408832-28-8
Formule: C₃₁H₃₃F₃N₁₀O₅S
Masse moléculaire:714.72

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Arg-TERRα Chemical Structure

CAS No.: 2408832-28-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Arg-TERRα is a mini-PROTAC targeting ERRα. Arg-TERRα induces ERRα degradation via the N-end rule pathway, thereby in inhibiting the proliferation and migration of MCF7 breast cancer cells. Arg-TERRα can be used for breast cancer research^[1]. (Pink: ERRα Target protein ligand; Blue: Ligands for E3 Ligase ligand (HY-N0455); Black: linker).

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Chemical Information

CAS No. 2408832-28-8
Masse moléculaire 714.72
Formule C₃₁H₃₃F₃N₁₀O₅S
SMILES

FC(F)(F)C(C=C(C=C1)C#N)=C1OC2=C(C=C(C=C2)/C=C3C(N(C(S\3)=O)CC4=CN(N=N4)CCCNC([C@@H](N)CCCNC(N)=N)=O)=O)OC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Chen X, et al. Mighty mini-PROTACs: an emerging class of degraders. Eur J Med Chem. 2026 Jan 5;301:118202. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Arg-TERRα

Voir tous les produits spécifiques à Isoform PROTACs

Voir tous les produits spécifiques à Isoform Estrogen Receptor/ERR

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Arg-TERRα Related Classifications

HY-186015 Related Classifications