BIO7662
BIO7662 is a specific α4β1 antagonist. BIO7662 can be used to study α4β1 integrin-ligand interactions.
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- CAS No.: 327613-10-5
- Formule: C38H48N6O8S
- Masse moléculaire:748.89
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
α4β1[1]
Chemical Information
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CAS No. 327613-10-5
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Masse moléculaire 748.89
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Formule C38H48N6O8S
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SMILES
O=C(O)[C@@H](NC([C@H]1N(S(=O)(C2=CC=CC=C2)=O)CCC1)=O)CCNC([C@@H](N(C)C(CC3=CC=C(NC(NC4=CC=CC=C4C)=O)C=C3)=O)CC(C)C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Egger LA, et al. A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence. J Pharmacol Exp Ther. 2003 Sep;306(3):903-13. [Content Brief]
[2]. Chen LL,et al. Evidence that ligand and metal ion binding to integrin alpha 4beta 1 are regulated through a coupled equilibrium. J Biol Chem. 2001 Sep 28;276(39):36520-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)