CDK4-IN-6
CDK4-IN-6 is a CDK4 inhibitor with an IC50 of 0.0011 μM. CDK4-IN-6 can be used for the research of breast cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 3120500-44-6
- Formule: C20H29FN6O3S
- Masse moléculaire:452.55
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
CDK4 0.0011 μM (IC50) |
In Vitro
Chemical Information
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CAS No. 3120500-44-6
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Masse moléculaire 452.55
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Formule C20H29FN6O3S
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SMILES
O[C@H](CN(S(=O)(C)=O)CC1)[C@@H]1NC2=NC=C3C(N([C@@H]4CCNC[C@@H]4F)C(C5CC5)=C3)=N2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Breast Cancer Modeling
Breast cancer is a heterogeneous cancer, and it has been distinguished into four subtypes: luminal A, luminal B, HER2-positive and basal-like. Molecular mutations, epigenetic alterations, hormone exposure and immune microenvironment are related to the progression of breast cancer.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)