CDK7 ligand 2
Based on 1 Customer Validation
CDK7 ligand 2 (Compound A6) is a CDK7 ligand. CDK7 ligand 2 can be used in the synthesis of PROTACs.
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- Pureté: 99.92%
- CAS No.: 2603381-71-9
- Formule: C26H30N6O4
- Masse moléculaire:490.55
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Activité biologique
Description
IC50 & Target
[1]|
CDK7 |
Chemical Information
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CAS No. 2603381-71-9
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Appearance Solid
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Masse moléculaire 490.55
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Formule C26H30N6O4
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Color White to off-white
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SMILES
O=C(NC1=NNC2=C1CN(C(N[C@@H](C3=CC=CC=C3)CN(C)C)=O)C2(C)C)C4=CC=C(C(O)=O)C=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 50 mg/mL (101.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (274 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0385 mL | 10.1926 mL | 20.3853 mL | 50.9632 mL |
| 5 mM | 0.4077 mL | 2.0385 mL | 4.0771 mL | 10.1926 mL | |
| 10 mM | 0.2039 mL | 1.0193 mL | 2.0385 mL | 5.0963 mL | |
| 15 mM | 0.1359 mL | 0.6795 mL | 1.3590 mL | 3.3975 mL | |
| 20 mM | 0.1019 mL | 0.5096 mL | 1.0193 mL | 2.5482 mL | |
| 25 mM | 0.0815 mL | 0.4077 mL | 0.8154 mL | 2.0385 mL | |
| 30 mM | 0.0680 mL | 0.3398 mL | 0.6795 mL | 1.6988 mL | |
| 40 mM | 0.0510 mL | 0.2548 mL | 0.5096 mL | 1.2741 mL | |
| 50 mM | 0.0408 mL | 0.2039 mL | 0.4077 mL | 1.0193 mL | |
| 60 mM | 0.0340 mL | 0.1699 mL | 0.3398 mL | 0.8494 mL | |
| 80 mM | 0.0255 mL | 0.1274 mL | 0.2548 mL | 0.6370 mL | |
| 100 mM | 0.0204 mL | 0.1019 mL | 0.2039 mL | 0.5096 mL |