Cyprocide-B
Cyprocide-B is activated by Cytochrome P450 and converted to electrophilic metabolites that selectively kill nematodes C. elegans. Cyprocide-B is promising for research of selective nematicide.
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- CAS No.: 49809-25-8
- Formule: C10H9ClN2OS
- Masse moléculaire:240.71
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
In Vitro
Cyprocide-B (50 µM, 3 days) is a selective nematicide with broad-spectrum activity in plant-parasitic nematodes (PPNs), and is safer for zebrafish than Tioxazafen (HY-136240)[1].
Cyprocide-B (25 μM, 24 h) is bioactivated by CYP-35D1 to produce a reactive electrophile in C. elegans[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Human cells, fungi, plant beneficial rhizobacteria
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Concentration:50 µM
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Incubation Time:3 days
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Result:Was relatively inactive against non-nematode phyla at the same concentration of killing nematodes in vitro.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 49809-25-8
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Masse moléculaire 240.71
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Formule C10H9ClN2OS
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SMILES
CCSC1=NN=C(C2=CC=C(Cl)C=C2)O1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)