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Cat. No.: HY-163804

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Cyprocide-B

Cyprocide-B is activated by Cytochrome P450 and converted to electrophilic metabolites that selectively kill nematodes C. elegans. Cyprocide-B is promising for research of selective nematicide.

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CAS No.: 49809-25-8
Formule: C₁₀H₉ClN₂OS
Masse moléculaire:240.71

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Cyprocide-B Chemical Structure

CAS No.: 49809-25-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Cyprocide-B is activated by Cytochrome P450 and converted to electrophilic metabolites that selectively kill nematodes C. elegans. Cyprocide-B is promising for research of selective nematicide^[1].

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In Vitro

Cyprocide-B (50 µM, 3 days) is a selective nematicide with broad-spectrum activity in plant-parasitic nematodes (PPNs), and is safer for zebrafish than Tioxazafen (HY-136240)^[1].
Cyprocide-B (25 μM, 24 h) is bioactivated by CYP-35D1 to produce a reactive electrophile in C. elegans^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

Human cells, fungi, plant beneficial rhizobacteria
Concentration:

50 µM
Incubation Time:

3 days
Result:

Was relatively inactive against non-nematode phyla at the same concentration of killing nematodes in vitro.

In Vivo

Cyprocide-B (60 μM, 24 h) has potential utility in preventing root infestation by M. incognita in a soil environment^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 49809-25-8
Masse moléculaire 240.71
Formule C₁₀H₉ClN₂OS
SMILES

CCSC1=NN=C(C2=CC=C(Cl)C=C2)O1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Knox J, et al. Cyprocide selectively kills nematodes via cytochrome P450 bioactivation[J]. Nat Commun. 2024 Jul 2;15(1):5529. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- In Vitro
- In Vivo
Chemical Information
Pureté et documentation
Références

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Cyprocide-B

Voir tous les produits spécifiques à Isoform Cytochrome P450

Voir tous les produits spécifiques à Isoform Parasite

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Cyprocide-B Related Classifications

HY-163804 Related Classifications