DLG-41nc
DLG-41nc is the negative control for DLG-41 (HY-180183). DLG-41nc shows no GAS41 YEATS domain inhibition (IC50: >50 μM in AlphaLISA). DLG-41 has anticancer activity against NSCLC.
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- Formule: C31H34N6O3S2
- Masse moléculaire:602.77
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
IC50: >50 μM (GAS41 YEATS) in AlphaLISA[1]
Chemical Information
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Masse moléculaire 602.77
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Formule C31H34N6O3S2
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SMILES
CC1(CN[C@@H](C1)C(NC2=NC=C(S2)C(N3CC(C4=NC=C(C5=C6C(C=CC=C6)=C(C=C5)CNC(CC)=O)S4)C3)=O)=O)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)